Results 11 to 20 of about 848,551 (267)

No association between myeloperoxidase gene rs2333227 G>A polymorphism and Alzheimer's disease risk: a meta-analysis and trial sequential analysis [PDF]

Journal of Integrative Neuroscience, 2022
Evidence suggests that there is a close association between myeloperoxidase (MPO) gene rs2333227 G>A polymorphism with Alzheimer’s disease (AD) susceptibility.
Zhi-Cheng Fang, Chen-Chen Mao, Ya-Jun Hu, Gong-Li Yang, Lan Zhou   +4 more
doaj   +1 more source

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate Non-Human Primate Hearts

Nature, 2014
Pluripotent stem cells provide a potential solution to current epidemic rates of heart failure by providing human cardiomyocytes to support heart regeneration.
James J. H. Chong, Xiulan Yang, C. Don, Elina Minami, Yen-Wen Liu, Jill J. Weyers, W. M. Mahoney, Benjamin Van Biber, Savannah M Cook, N. Palpant, Jay A. Gantz, James A. Fugate, V. Muskheli, G. M. Gough, Keith W. Vogel, C. Astley, C. Hotchkiss, A. Baldessari, Lil Pabon, H. Reinecke, E. Gill, Veronica Nelson, H. Kiem, M. Laflamme, C. Murry, V. N. J. C. Performed Macaque, C. H. Performed Echocardiography, B. V. B. Hesc-Cm, M. A. L. Microcomputed, W. M. M. Immunohistochemistry, Y. W. L. Figures   +30 more
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Hadassah, provider of 'Regulatory-Ready' pluripotent clinical-grade stem cell banks

Stem Cell Research, 2020
The Hadassah hESC Research Center's aim is to be a supplier of clinical and research-grade human embryonic stem cell (hESC) lines. In 2012, we derived the first three entirely GMP-compliant and xeno-free, fully-characterised, feeder-dependent (human ...
Shelly E Tannenbaum, Orna Singer, Yaniv Gil, Yael Berman-Zaken, Nili Ilouz, Hanita Khaner, Miriam Haimov, Benjamin E Reubinoff   +7 more
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Embryonic Stem Cell

Definitions, 2020
Embryonic stem (ES) cells are cells derived from the inner cell mass of the early embryo that can be propagated indefinitely in the primitive undifferentiated state while remaining pluripotent.

semanticscholar   +1 more source

Nuclear FAM289-Galectin-1 interaction controls FAM289-mediated tumor promotion in malignant glioma

Journal of Experimental & Clinical Cancer Research, 2019
Background FAM92A1–289(abbreviated FAM289) is recognized as one of the newly-discovered putative oncogenes. However, its role and molecular mechanisms in promoting cancer progression has not yet been elucidated.
Xing Rong Guo, Mu Yu Wu, Long Jun Dai, Yu Huang, Meng Ye Shan, Shi Nan Ma, Jue Wang, Hao Peng, Yan Ding, Qiu Fang Zhang, Jun Ming Tang, Xu Zhi Ruan, Dong Sheng Li   +12 more
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Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis

Oncogenesis, 2023
The interplay between hepatocellular carcinoma (HCC) cells and the tumor microenvironment is essential for hepatocarcinogenesis, but their contributions to HCC development are incompletely understood.
Yujiu Gao, Yue Yuan, Shu Wen, Yanghui Chen, Zongli Zhang, Ying Feng, Bin Jiang, Shinan Ma, Rong Hu, Chen Fang, Xuzhi Ruan, Yahong Yuan, Xinggang Fang, Chao Luo, Zhongji Meng, Xiaoli Wang, Xingrong Guo   +16 more
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Vagus nerve stimulation‐induced stromal cell‐derived factor‐l alpha participates in angiogenesis and repair of infarcted hearts

ESC Heart Failure, 2023
Aims We aim to explore the role and mechanism of vagus nerve stimulation (VNS) in coronary endothelial cells and angiogenesis in infarcted hearts. Methods and results Seven days after rat myocardial infarction (MI) was prepared by ligation of the left ...
Yan Wang, Yun Liu, Xing‐yuan Li, Lu‐yuan Yao, MagdaleenaNaemi Mbadhi, Shao‐Juan Chen, Yan‐xia Lv, Xin Bao, Long Chen, Shi‐You Chen, Jing‐xuan Zhang, Yan Wu, Jing Lv, Liu‐liu Shi, Jun‐ming Tang   +14 more
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Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm

Genome Biology, 2016
Human pluripotent stem cells offer the best available model to study the underlying cellular and molecular mechanisms of human embryonic lineage specification.
Li-Fang Chu, Ning Leng, Jue Zhang, Zhonggang Hou, Daniel Mamott, D. Vereide, Jeea Choi, C. Kendziorski, R. Stewart, J. Thomson   +9 more
semanticscholar   +1 more source

Integrin-Associated Focal Adhesion Kinase Protects Human Embryonic Stem Cells from Apoptosis, Detachment, and Differentiation

Stem Cell Reports, 2016
Human embryonic stem cells (hESCs) can be maintained in a fully defined niche on extracellular matrix substrates, to which they attach through integrin receptors.
Loriana Vitillo, Melissa Baxter, Banu Iskender, Paul Whiting, Susan J. Kimber   +4 more
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Serine protease PRSS56, a novel cancer-testis antigen activated by DNA hypomethylation, promotes colorectal and gastric cancer progression via PI3K/AKT axis

Cell & Bioscience, 2023
Background Cancer/testis (CT) antigens/genes are usually overexpressed in cancers and exhibit high immunogenicity, making them promising targets for immunotherapy and cancer vaccines. The role of serine protease PRSS56 in cancers remains unknown to date.
Dandan Li, Lingyun Xia, Pan Huang, Zidi Wang, Qiwei Guo, Congcong Huang, Weidong Leng, Shanshan Qin   +7 more
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