Results 61 to 70 of about 564,991 (206)

A strategy to ensure safety of stem cell-derived retinal pigment epithelium cells [PDF]

open access: yes, 2016
Cell replacement and regenerative therapy using embryonic stem cell-derived material holds promise for the treatment of several pathologies. However, the safety of this approach is of prime importance given the teratogenic potential of residual stem ...
Choudhary, P, Whiting, PJ
core   +2 more sources

Network toxicology and molecular docking to investigate the mechanism of bisphenol A toxicity in human diabetic cardiomyopathy

open access: yesEcotoxicology and Environmental Safety
Bisphenol A (BPA), a ubiquitous endocrine-disrupting chemical, is widely used in polymers, plasticizers, and food packaging, raising significant concerns for human health. Growing evidence links BPA exposure to cardiovascular diseases, including diabetic
Bo Li, Xu Zhao, Yan Ding, Yi Zhang
doaj   +1 more source

Lipofection improves gene targeting efficiency in E14 TG2a mouse embryonic stem cells [PDF]

open access: yes, 2009
Electroporation has been the method of election for transfection of murine embryonic stem cells for over 15 years; however, it is a time consuming protocol because it requires large amounts of DNA and cells, as well as expensive and delicate equipment ...
ALONSO MORALES, ROGELIO ALEJANDRO   +13 more
core  

CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

open access: yesCell Death and Disease
Insufficient liver regeneration increases the risk of postoperative liver failure following liver transplantation or partial hepatectomy (PHx). Numerous growth factors and cytokines are related to liver regeneration; however, the underlying mechanisms ...
Qun Zhao   +11 more
doaj   +1 more source

Distinct molecular profile and restricted stem cell potential defines the prospective human cranial neural crest from embryonic stem cell state

open access: yesStem Cell Research, 2020
Neural crest cells are an embryonic multipotent stem cell population. Recent studies in model organisms have suggested that neural crest cells are specified earlier than previously thought, at blastula stages.
Maneeshi S. Prasad   +3 more
doaj   +1 more source

Conventional pluripotency markers are unspecific for bovine embryonic-derived cell-lines [PDF]

open access: yes, 2013
Bovine embryonic stem cells are of potentially big value in transgenic research and studies of lineage commitment and development. Nevertheless, key aspects of the establishment of bovine embryonic stem cells such as the identification of specific ...
Caamaño, J.N. (José)   +6 more
core  

Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil [PDF]

open access: yes, 2018
Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs) in the regulation of stem cell biology, specifically focusing on maintenance, differentiation, and stress responses in the context of several stem cell ...
Aljoufi, Arafat   +3 more
core   +1 more source

A Bibliometric Analysis of Publications on Pluripotent Stem Cell Research [PDF]

open access: yesCell Journal, 2015
Objective: Human pluripotent stem cells are self-renewing cells with the ability to differentiate into a variety of cells and are viewed to have great potential in the field of regenerative medicine.
Changshuan L. Lin, Yuh-Shan Ho
doaj  

Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]

open access: yes, 2011
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo   +6 more
core   +2 more sources

Human stem cells and articular cartilage regeneration. [PDF]

open access: yes, 2012
The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki   +2 more
core   +4 more sources

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