Results 61 to 70 of about 541,010 (202)

Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. [PDF]

, 2017
Human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced PSCs (iPSCs), represent potentially unlimited cell sources for clinical applications. Previous studies have suggested that hPSCs may benefit from immune privilege and
Allard, Patrick, Chang, Kai-Wei, Chen, Hsin-Fu, Chou, Wen-Hsi, Ghelfi, Elisa, Ho, Hong-Nerng, Huang, Mei-Chi, Jan, Pey-Shynan, Lin, Shau-Ping, Lu, Chen-Yu, Wu, Chia-Eng, Wu, Fang-Chun, Yu, Chen-Wei   +12 more
core   +1 more source

In ‌‌‌Vitro Differentiation Of Mouse Embryonic Stem Cells Into Lymphoid Lineage By Defined Growth Factors [PDF]

پیاورد سلامت, 2012
Background and Aim: Embryonic stem cells are identified with two unique characteristics. First, they can be maintained and expanded as pure populations of undifferentiated cells, a characteristic which is known as self renewal aspect of embryonic stem ...
Majid Mossahebi Mohammadi, Saeid Kaviani, Masoud Soleimani, Abbas Haji Fathali, Zahra Zonoubi, Saeid Abroun, Gholamreaz Khamisipour, Mina Soufi Zomorod   +7 more
doaj   +1 more source

Evaluation of human umbilical cord blood as a source of embryonic stem cells [PDF]

, 2013
Human umbilical cord blood (HUCB) has been poorly characterised as a source of embryonic stem cells (ESCs). The aim of this study, therefore, was to evaluate HUCB as source of mesenchymal stem cells (MSCs) with embryonic characteristics.
El-Sheemy, Mohamed, Eremin, Oleg, Hussain, Issam, Magd, Salah A.   +3 more
core   +2 more sources

Liver-specific expression of ANGPTL8 promotes Alzheimer’s disease progression through activating microglial pyroptosis

Journal of Neuroinflammation
Introduction Liver dysfunction contributes to Alzheimer’s disease (AD) pathogenesis, and evidence suggests that the liver is involved in amyloid β (Aβ) clearance, and regulates Aβ deposition in the brain.
Jiarui Wei, Lin Hu, Shufan Xu, Fan Yang, Fusheng Liao, Ying Tang, Xin Shen, Xiaoqiao Zhang, Xinggang Fang, Yifan Li, Li Ding, Zhuo Chen, Shanchun Su, Junhua Cheng, Yong Huang, Qian Chen, Daqing Ma, Qiufang Zhang, Xingrong Guo   +18 more
doaj   +1 more source

The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells

Cell & Bioscience, 2017
Increasing evidence indicates that embryonic stem cell specific microRNAs (miRNAs) play an essential role in the early development of embryo. Among them, the miR-290-295 cluster is the most highly expressed in the mouse embryonic stem cells and involved ...
Kai Yuan, Wen-Bing Ai, Lin-Yan Wan, Xiao Tan, Jiang-Feng Wu   +4 more
doaj   +1 more source

Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis. [PDF]

, 2014
Adult stem cells grow poorly in vitro compared to embryonic stem cells, and in vivo stem cell maintenance and proliferation by tissue niches progressively deteriorates with age.
CONBOY, Irina M, Conboy, Michael, Mamiya, Hikaru, Schaffer, David, Schlesinger, Christina, Yousef, Hanadie, Zeiderman, Matthew   +6 more
core   +3 more sources

The epigenetic bivalency of core pancreatic β-cell transcription factor genes within mouse pluripotent embryonic stem cells is not affected by knockdown of the polycomb repressive complex 2, SUZ12.

PLoS ONE, 2014
This study assesses changes in activator and repressor modifications to histones associated with the core transcription factor genes most highly upregulated or downregulated in pancreatic β-cells relative to expression in an embryonic stem cell line ...
Jennifer C Y Wong, Michelle M Jack, Yan Li, Christopher O'Neill   +3 more
doaj   +1 more source

Constraints to Progress in Embryonic Stem Cells from Domestic Species [PDF]

, 2013
Domestic animal embryonic stem cells are of potentially big value in transgenic research and studies of lineage commitment and development. Unfortunately, despite many efforts, validated embryonic stem cell lines in species other than mice and primates ...
Caamaño, J.N. (José), Díez, C., Gómez, E., Molina, I., Muñoz, M., Trigal, B.   +5 more
core  

Pig Pluripotent Stem Cells as a Candidate for Biomedical Application

Journal of Animal Reproduction and Biotechnology, 2019
Stem cells are progenitor cells that are capable of self-renewal and differentiation into various cells. Especially, pluripotent stem cells (PSCs) have in vivo and in vitro differentiation capacity into three germ layers and can proliferate infinitely ...
Kwang-Hwan Choi, Chang-Kyu Lee
doaj   +1 more source

LINE-1 Based Insertional Mutagenesis Screens to Identify Genes Involved in Embryonic Stem Cell Differentiation

, 2016
Background: Knowledge of the intrinsic properties of embryonic stem cells is essential before the possibility of using these cells for therapeutic purposes becomes a reality. Insertional mutagenesis screens are widely used to identify genes sufficient to
Lee, Sung-Hun, Rangasamy, Danny
core   +1 more source