Results 81 to 90 of about 506,868 (329)

Induced pluripotent stem cells, a giant leap for mankind therapeutic applications [PDF]

, 2019
Induced pluripotent stem cells (iPSC) technology has propelled the field of stem cells biology, providing new cells to explore the molecular mechanisms of pluripotency, cancer biology and aging.
Bragança, José, Lopes, João A. P., Santos, João, Silva, Leonardo   +3 more
core   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

Pig Pluripotent Stem Cells as a Candidate for Biomedical Application

Journal of Animal Reproduction and Biotechnology, 2019
Stem cells are progenitor cells that are capable of self-renewal and differentiation into various cells. Especially, pluripotent stem cells (PSCs) have in vivo and in vitro differentiation capacity into three germ layers and can proliferate infinitely ...
Kwang-Hwan Choi, Chang-Kyu Lee
doaj   +1 more source

Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D [PDF]

, 2007
Phosphoinoisitide dependent kinase l (PDK1) is proposed to phosphorylate a key threonine residue within the catalytic domain of the protein kinase C (PKC) superfamily that controls the stability and catalytic competence of these kinases.
April P. Kelly, Balendran, Brandlin, C. David Wood, Collins, Czerwinski, Doreen A. Cantrell, Dutil, Edwards, Gao, Hinton, Hinton, Lawlor, LeGood, Matthews, Matthews, Matthews, McManus, Mora, Mora, Pracht, Rey, Rozengurt, Sharon A. Matthews, Sonnenburg, Stempka, Stempka, Storz, Wang, Williams   +29 more
core   +3 more sources

Ultra‐Effective Light‐Activated Antibacterial Activity via Carboxyl Functionalized Graphene Quantum Dots and Films

Advanced Functional Materials, EarlyView.
Carboxyl‐functionalized graphene quantum dots (cGQDs) exhibit high singlet oxygen quantum yield due to strong spin–orbit coupling. cGQDs achieve minimum bactericidal concentration of only 0.4 µg mL−1 against S. aureus under low‐intensity illumination.
Muhammad Hassnain, Laure S. van Hofwegen, Humeyra Nur Kaleli, Temirlan Kubanaliev, Zafer Eroglu, Asim Onal, Payal P. S. Balraadjsing, Onder Metin, Fahri Alkan, Sebastian A. J. Zaat, Sedat Nizamoglu   +10 more
wiley   +1 more source

Biointerfacing with AgBiS2 Quantum Dots for Pseudocapacitive Photostimulation

Advanced Functional Materials, EarlyView.
It is demonstrated that AgBiS2 quantum dots exhibit unique photoinduced pseudocapacitive charge transfer properties, enabling efficient light‐to‐electrical energy conversion. These quantum dots facilitate enhanced light absorption and transduction when integrated with ZnO nanowires, which serve as an effective charge transport medium.
Ridvan Balamur, Tarik Safa Kaya, Selin Sariyer, Hümeyra Nur Kaleli, Asim Onal, Ugur Berkay Caliskan, Murat Hasanreisoğlu, Rezan Demir‐Cakan, Sedat Nizamoglu   +8 more
wiley   +1 more source

Epigenetic memory in induced pluripotent stem cells. [PDF]

, 2010
Somatic cell nuclear transfer and transcription-factor-based reprogramming revert adult cells to an embryonic state, and yield pluripotent stem cells that can generate all tissues.
Aryee, MJ, Cahan, P, Cunniff, KC, Daley, GQ, Doi, A, Ehrlich, LIR, Feinberg, AP, Hanna, J, Hongguang, H, Irizarry, RA, Jaenisch, R, Ji, H, Jung, N, Kim, J, Kim, K, McKinney-Freeman, S, Murakami, P, Naveiras, O, Ng, K, Orkin, SH, Seita, J, Takeuchi, A, Weissleder, R, Weissman, IL, Wen, B, Yabuuchi, A, Yoon, TJ, Zhao, R   +27 more
core  

Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7 [PDF]

, 2016
The transcription factor Pax7 plays a key role during embryonic myogenesis and in adult organisms in that it sustains the proper function of satellite cells, which serve as adult skeletal muscle stem cells. Recently we have shown that lack of Pax7 does
Amini-Nik S, Amthor H, Anna Fogtman, Areta M. Czerwinska, Bober E, Czerwinska AM, Franz T, Gerdes J, Goulding M, Iwona Grabowska, Joanna Nowacka, Karolina Archacka, Katarzyna Jańczyk-Ilach, Magdalena Aszer, Mansouri A, Maria A. Ciemerych, Marta Koblowska, Martelli F, Robertson E, Roksana Iwanicka-Nowicka, Savatier P, Savatier P, Swierczek B, Sylwia Gawrzak, Verploegen S, Williams BA   +25 more
core   +2 more sources

Embryonic Stem Cells: Introducing Exogenous Regulators into Embryonic Stem Cells [PDF]

, 2011
The application of embryonic stem (ES) cells to research and therapy has been a landmark development in science. Cell therapy using ES cells depends on the progress of the stable culture conditions and differentiation induction methods. ES cells were first obtained directly from inner cell masses (ICMs) of blastocysts by Evans and Kaufman (1981), and ...
openaire   +3 more sources