Results 61 to 70 of about 588,275 (307)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

THE EFFORTS TO IMPROVE EMPLOYEE PERFORMANCE THROUGH EMPLOYEE ENGAGEMENT AND ORGANIZATIONAL COMMITMENT OF CV. NIPSON PAINT SURABAYA PRODUCTION DEPARTMENT

Manajemen dan Bisnis, 2017
This study aims to examine the effect of employee engagement and organizational commitment to improving employee performance. The statistical analysis used in this study was SEM (Structural Equation Modeling) by collecting data through questionnaires to ...
Yusieni ., Joseph L. Eko Nugroho
doaj   +1 more source

Pengaruh Komitmen Organisasi Dan Keinginan Sosial Terhadap Partisipasi Anggaran [PDF]

, 2012
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Mayuni, Fifi
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Motivation and Organizational Commitment on Loyalty and Islamic Banking Employee Performance

Al-Intaj
Purpose: The purpose of this study was to determine the effect of motivation and organizational commitment on the loyalty and performance of Islamic bank employees, either directly or through mediating variables.
Zulkifli Zulkifli, Hamzah Hamzah, Zulfadli Hamzah, Muhammad Arif, Hamsal Hamsal, Syahiza Arsad   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The impact of internal marketing on job satisfaction, organizational commitment, and employee loyalty

Jurnal Ekonomi dan Bisnis
Internal marketing is critical in influencing job satisfaction and organizational commitment.  Accordingly, this research analyzes the impact of internal marketing on job satisfaction, organizational commitment, and employee loyalty at AirNav Indonesia ...
Rizky Ananda Pratama, Rina Anindita
doaj   +1 more source

ANALISIS PENGARUH MOTIVASI KERJA DAN KOMITMEN ORGANISASIONAL TERHADAP KINERJA KARYAWAN (Studi Pada PT. BPR Estetika Artha Guna Semarang) [PDF]

, 2011
The purpose of this research is to investigate the effects of employee motivation, and organizational commitment on employee performance. The study was conducted at BPR Estetika Artha Guna, the sample size is about 69 employee, using the Regression ...
KRISTIWARDHANA, Aryo, NUGRAHENI, Rini
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Organisational commitment as a predictor of job satisfaction, employee well being, absenteeism and intention to stay in the New Zealand Aged Care Sector : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

, 1999
This study, one of the first in the New Zealand aged care sector, examined the predictability of organisational commitment on job satisfaction, employee well being, absenteeism and intention to stay.
Parr, Richard
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