Results 31 to 40 of about 167,070 (236)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Perancangan Kerangka Penilaian Kinerja Manajer Operasional Sistem Menggunakan Pendekatan Balanced Scorecard pada PT Pegadaian (Persero) [PDF]

open access: yes, 2012
Pegadaian is a State Owned Enterprises (SOEs) is engaged in financing, with the main business is pawning services. The level of competition in the mortgage sector is currently very tight, and will continue to increase the complexity and
Mahendra, I. (Irfan)
core   +3 more sources

The Impact of Performance Appraisal, Reward System, Job Stress, and Work Life Conflict to Employee Performance [PDF]

open access: yes, 2014
Employee Performance is an important part in a company or organization. It plays a very important role in an organization because performance of the company or organization largely depends on the performance of its employee.
Rumambie, Y. F. (Yuliana)
core  

Importance of system and leadership in performance appraisal [PDF]

open access: yes, 2012
Purpose Performance - appraisal is used internationally to improve employee performance, also in the educational field. However, doubts exist about the effectiveness of performance appraisal. This study-aims to contribute by expanding the knowledge about
Devos, Geert, Tuytens, Melissa
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

PERFORMANCE APPRAISAL MANAGEMENT - A MOTIVATION TO EMPLOYEE

open access: yes, 2022
Human resource managers have traditionally accorded employee performance as a prime focus. As a result, several performance appraisal techniques have been devised to help establish employee performance. In contemporary times, performance appraisals have been extended beyond rating the employee's performance to aspects such as motivation.
Dr. G. Vignesh, C. Princy
openaire   +1 more source

Dampak Penilaian Prestasi Kerja terhadap Promosi Jabatan pada Sekolah Permata Harapan II Batam [PDF]

open access: yes, 2017
Human Resources has an important role in a company. Company is a tool to achieve goals that must be able to provide clarity of status to someone in the working environment, both in terms of ties, position and role.
UPB, J. I. (Jurnal)
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

IMPLEMENTASI IMPORTANCE AND PERFORMANCE ANALYSIS (IPA) DALAM PELAKSANAAN PENILAIAN KINERJA KARYAWAN (PNS) (Studi pada Kementerian Pekerjaan Umum Dan Perumahan Rakyat, SNVT PJPA Pemali-Juana PPK PAT dan PPK PAB) [PDF]

open access: yes, 2017
This study aims to examine the implementation of performance appraisal at the Ministry of Public Works and Public Housing, SNVT PJPA Pemali-Juana PPK PAT and PPK PAB.
NUGRAHA, Nur Chaida, YUNIAWAN , Ahyar
core  

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