Results 91 to 100 of about 33,430 (260)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effects of executive-level leader's transformational leadership on talent retention in post merger and acquisition in China

, 2014
Talent retention, which can be defined as organizational practices aiming at maintaining the continued employment of high potential and high-performing incumbents to fill the key positions that have the potential to have an impact on the competitive ...
Zhang, J
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What effect do formalised human resource procedures such as contracts and appraisals have on employee motivation in the hospitality industry [PDF]

, 2009
This paper examines the effects of formalised HR procedures on employee motivation in the hospitality sector. It has long been accepted that staff turnover, the ultimate sign of poor employee motivation, is very high within the hospitality industry ...
Powell, Victoria
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Talent management dan konsekuensinya terhadap employee engagement dan employee retention [PDF]

, 2020
To gain a competitive advantage, employee engagement is indispensable. Therefore, an effective talent management system is needed in order to increase employee engagement.
Srimulyani, Veronika Agustini
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TECHNOLOGY READINESS, DATA QUALITY AND EMPLOYEE RETENTION IN SELECTED MICROFINANCE BANKS IN KWARA STATE

Malete Journal of Accounting and Finance
Employee retention remains a persistent challenge in many financial institutions, particularly microfinance banks where operational stability and customer relationships depend heavily on experienced employees.
Kamoru Lanre AKANBI, Abdulazeez Alhaji SALAU, Rahman Olalekan BAMIDELE   +2 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

The Effect of Training on Employee Engagement and Employee Retention [PDF]

, 2022
Attracting the right people is not the only challenge, however, the main challenge is to find a way to engage and retain talented employees. This study aims to examine the relationship between training, employee engagement and employee retention.
Dia, Lynn
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Recruitment and Retention in Front-line Services: the case of childcare [PDF]

In this paper we highlight how problems of recruitment and retention in front-line services create a particular challenge to traditional HRM models and solutions.
Mark Smith, Gwen Oliver, Marilyn Carroll, Sirin Sung   +3 more
core  

Strategies for Improving Employee Retention

, 2022
This paper will focus on ways to improve employee retention in the workplace. Employee retention can have a huge impact on the overall success or failure of an organization. There are many steps that an organization can take to improve its turnover rate.
Kuykendall, Valerie
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