Results 131 to 140 of about 1,592,470 (309)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Work and well-being over time: lone mothers and their children [PDF]

open access: yes, 2008
This report provides findings from the third wave of a qualitative longitudinal study, which began in 2003, following a sample of lone mothers who elected to move into employment supported by tax credits following a period of unemployment in receipt of ...
Millar, Jane., Ridge, Tess
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Supported Employement: Recommendations for successful implementation in South Africa

open access: yesSouth African Journal of Occupational Therapy, 2011
Introduction: This article reports on the findings of a descriptive qualitative study in which supported employment (SE), as a potential strategy to facilitate the employment of persons with disability in the open labour market in South Africa, was ...
Lana van Niekerk   +6 more
doaj  

Where is full employment? [PDF]

open access: yes
Unemployment in Australia is now at its lowest in over 30 years. This experience of low rates of unemployment has prompted a number of statements that the Australian economy is at or very close to full employment. However, even though unemployment is low
Mcdonald, Ian Martin
core   +1 more source

Career learning journeys of Derby and Derbyshire NEETs [PDF]

open access: yes, 2011
Young people (aged under 25 years) typically represent a third of all unemployed people across Derby and Derbyshire. The numbers of young people aged between 16 and 18 years old who are either not in education, employment or training (known as NEETs) in ...
Hutchinson, Jo   +2 more
core   +1 more source

Supported Employment

open access: yes, 2010
Art?culo para la "International Encyclopedia of Rehabilitation" que est? desarrollando en un proyecto internacional el Center for International Rehabilitation Research Information and Exchange (CIRRIE), de la Universidad de Buffalo, y el Laboratoire d?informatique et de terminologie de la r?adaptation et de l?int?gation sociale (LITRIS), del Institut ...
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Evaluating the Employment Impact of Business Incentive Programs in EU Disadvantaged Areas. A case from Northern Italy [PDF]

open access: yes
Business incentive programs have been increasingly popular within the EU as regional economic development tools to promote employment growth in areas with severely distressed and/or declining socio-economic conditions. Reliable evidenced on the effective
Bondonio, Daniele
core  

Home - About - Disclaimer - Privacy