Inducing transient enantiomeric excess in a molecular quantum racemic mixture with microwave fields [PDF]
Nature Communications, 2023 There is growing interest in controlling and manipulating molecules using external field. Here the authors demonstrate microwave induced transient enantiomeric excess in a state-selective benzyl alcohol using microwave six-wave mixing.
Wenhao Sun +5 more
doaj +5 more sources
High Enantiomeric Excess In-Loop Synthesis of d-[methyl-11C]Methionine for Use as a Diagnostic Positron Emission Tomography Radiotracer in Bacterial Infection. [PDF]
ACS Infect Dis, 2020 Currently, there exists no accurate, non-invasive clinical imaging method to detect living bacteria in vivo. Our goal is to provide a positron emission tomography (PET) method to image infection by targeting bacteria-specific metabolism. Standard of care
Stewart MN +13 more
europepmc +4 more sources
Data-Driven Prediction of Circular Dichroism-Based Calibration Curves for the Rapid Screening of Chiral Primary Amine Enantiomeric Excess Values. [PDF]
J Am Chem Soc, 2022 Here, we describe the prediction of the circular dichroism (CD) response of a three-component chiroptical sensor for enantiomeric excess (ee) determination of chiral amines using a multivariate fit to electronic and steric parameters.
Howard JR +4 more
europepmc +4 more sources
Prebiotic formation of enantiomeric excess D-amino acids on natural pyrite [PDF]
Nature CommunicationsD-amino acids, found in excess in a minority of organisms and crucial for marine invertebrates, contrast with the more common L-amino acids in most life forms.
Ruiqi Li +5 more
doaj +4 more sources
Amplification of enantiomeric excess by dynamic inversion of enantiomers in deracemization of Au38 clusters [PDF]
Nature Communications, 2020 Symmetry breaking and amplification processes play a fundamental role in nature and technology. Here, the authors show that the interplay between racemization and ligand exchange leads to amplification of enantiomeric excess of intrinsically chiral metal
Yanan Wang +2 more
doaj +3 more sources
Determination of Enantiomeric Excess in Confined Aprotic Solvent. [PDF]
ACS ElectrochemThe validation of the stereochemical purity of synthesized compounds is a requisite for the fine-chemical industry, particularly in the production of enantiopure drug compounds. However, most methodologies employed in the determination of enantiopurity require carefully chosen chiral GC or HPLC columns, increasing associated cost, analysis time, and ...
Farrell EB +5 more
europepmc +4 more sources
Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point [PDF]
Advanced Science, 2023 Enantiomeric excess (ee) is an essential indicator of chiral drug purification in the pharmaceutical industry. However, to date the ee determination of unknown concentration enantiomers generally involves two separate techniques for chirality and ...
Zhiyang Xu +6 more
doaj +4 more sources
Solubility of chiral species as function of the enantiomeric excess [PDF]
Journal of Pharmacy and Pharmacology, 2015 Abstract The solubility of racemizable and nonracemizable chiral species is discussed in terms of: enantiomeric excess, nature of solvent and the solid phases, which are in equilibrium with a saturated solution. Stable and metastable equilibria are contemplated by an extensive used of phase diagrams.
Gérard Coquerel
semanticscholar +6 more sources
Concentration-Independent Stereodynamic g-Probe for Chiroptical Enantiomeric Excess Determination
Journal of the American Chemical Society, 2017 Enantiomeric excess (ee) determination is crucial in many aspects of science, from synthesis to materials. Within this subject, coupling molecular sensors with chiroptical techniques is a straightforward approach to the stereochemical analysis of chiral molecules, especially in terms of process immediacy and labor.
Paolo Zardi +3 more
semanticscholar +5 more sources
On the origins of life's homochirality: Inducing enantiomeric excess with spin-polarized electrons. [PDF]
Proc Natl Acad Sci U S A, 2022 Significance Essential biomolecules, like amino acids and sugars, are chiral; they exist in mirror symmetrical pairs named enantiomers. However, modern life selectively uses only one of the enantiomers. The origin of this chiral symmetry breaking remains
Ozturk SF, Sasselov DD.
europepmc +3 more sources