Results 41 to 50 of about 691,764 (293)

From Microorganisms to Biosignatures: Subcritical Water Extraction as a Sample Preparation Technique for Future Life Detection Missions

open access: yesGeophysical Research Letters, 2022
Amino acids are important targets in the search for life beyond Earth. The types of amino acids, their relative abundances, and enantiomeric excess all serve as biosignatures.
Zuzana Cieslarova   +3 more
doaj   +1 more source

Cannabis through the looking glass: chemo- and enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography [PDF]

open access: yes, 2017
By using the Inverted Chirality Columns Approach (ICCA) we have developed an enantioselective UHPSFC method to determine the enantiomeric excess (ee) of (-)-Δ(9)-THC in medicinal marijuana (Bedrocan®).
Cavazzini, A   +7 more
core   +2 more sources

Solubility of chiral species as function of the enantiomeric excess [PDF]

open access: yesJournal of Pharmacy and Pharmacology, 2015
Abstract The solubility of racemizable and nonracemizable chiral species is discussed in terms of: enantiomeric excess, nature of solvent and the solid phases, which are in equilibrium with a saturated solution. Stable and metastable equilibria are contemplated by an extensive used of phase diagrams.
G. Coquerel
semanticscholar   +4 more sources

Comparison of reversed-phase enantioselective HPLC methods for determining the enantiomeric purity of (S)-omeprazole in the presence of its related substances

open access: yesJournal of Pharmaceutical Analysis, 2016
A simple analytical high-performance liquid chromatography (HPLC) method was applied for the enantiomeric excess determination of esomeprazole ((S)-OME), the enantiopure active ingredient contained in drug products, in the presence of its potential ...
Bruno Gallinella   +5 more
doaj   +1 more source

Uni-directional polymerization leading to homochirality in the RNA world [PDF]

open access: yes, 2005
The differences between uni-directional and bi-directional polymerization are considered. The uni-directional case is discussed in the framework of the RNA world. Similar to earlier models of this type, where polymerization was assumed to proceed in a bi-
Andersen, A. C.   +3 more
core   +2 more sources

Discovery of (S)-3′-hydroxyblebbistatin and (S)-3′-aminoblebbistatin : polar myosin II inhibitors with superior research tool properties [PDF]

open access: yes, 2017
In search of myosin II inhibitors with superior research tool properties, a chemical optimization campaign of the blebbistatin scaffold was conducted in this paper. (S)-Blebbistatin is the best known small-molecule inhibitor of myosin II ATPase activity.
Bracke, Marc   +6 more
core   +1 more source

Amino Acids in the Universe

open access: yesBIO Web of Conferences, 2014
What is the role played by amino acids in the chemistry of the interstellar medium and the emergence of life on the early Earth? Are they really the primary key compounds as free amino acids?
Guillemin J-C.
doaj   +1 more source

Theoretical Prediction and Experimental Verification of ees Versus Time in Biocatalytic Resolution and its Application in a Bioresolution-inversion Process

open access: yesMATEC Web of Conferences, 2015
A systematic theoretical derivation of bioresolution-inversion process was made. An equation was derived between the maximum ee value of final product (eef(max)) and enantiomeric ratio (E) of a reaction. The corresponding equations of conv.(max), eep(max)
Xu Yi, Zhou Dan, Chen Jianbo
doaj   +1 more source

Determination of enantiomeric excess in amine derivatives with molecular self-assemblies. [PDF]

open access: yesAngewandte Chemie, 2015
AbstractWe report the first fluorescence‐based assay for the rapid determination of the ee value of amines, amino alcohols, and amino acid esters. The method uses the self‐assembly of 2‐formylphenylboronic acid with a chiral diol and a chiral amine or derivatives (of unknown chirality) to produce two diastereomeric iminoboronates that differ in their ...
Elena G. Shcherbakova   +4 more
semanticscholar   +3 more sources

Total Chiral Symmetry Breaking during Crystallization: Who needs a "Mother Crystal"? [PDF]

open access: yes, 2005
Processes that can produce states of broken chiral symmetry are of particular interest to physics, chemistry and biology. Chiral symmetry breaking during crystallization of sodium chlorate occurs via the production of secondary crystals of the same ...
Cristobal Viedma   +7 more
core   +3 more sources

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