Results 91 to 100 of about 119,652 (298)

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives

Molecules, 2018
Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1,4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles in the presence of β-isocupreidine catalyst are reported.
Fernando Auria-Luna, Eugenia Marqués-López, Raquel P. Herrera   +2 more
doaj   +1 more source

Enantioselective Total Synthesis of (+)-Salvileucalin B [PDF]

, 2011
An enantioselective total synthesis of the diterpenoid natural product (+)-salvileucalin B is reported. Key findings include a copper-catalyzed arene cyclopropanation reaction to provide the unusual norcaradiene core and a reversible retro ...
Levin, Sergiy, Nani, Roger R., Reisman, Sarah E.   +2 more
core   +1 more source

Formal enantioconvergent substitution of alkyl halides via catalytic asymmetric photoredox radical coupling

Nature Communications, 2018
Enantioselective substitution reactions of racemic alkyl halides are inherently limited by the specificity of their stereochemical course (SN1 or SN2).
Jiangtao Li, Manman Kong, Baokun Qiao, Richmond Lee, Xiaowei Zhao, Zhiyong Jiang   +5 more
doaj   +1 more source

Mirror symmetry breaking with limited enantioselective autocatalysis and temperature gradients: a stability survey

, 2012
We analyze limited enantioselective (LES) autocatalysis in a temperature gradient and with internal flow/recycling of hot and cold material. Microreversibility forbids broken mirror symmetry for LES in the presence of a temperature gradient alone.
Blanco, Celia, Crusats, Joaquim, El-Hachemi, Zoubir, Hochberg, David, Moyano, Albert, Ribó, Josep M.   +5 more
core   +1 more source

Enantioselective Hydrolysis of Styrene Oxide and Benzyl Glycidyl Ether by a Variant of Epoxide Hydrolase from Agromyces mediolanus

Marine Drugs, 2019
Enantiopure epoxides are versatile synthetic intermediates for producing optically active pharmaceuticals. In an effort to provide more options for the preparation of enantiopure epoxides, a variant of the epoxide hydrolase (vEH-Am) gene from a marine ...
Huoxi Jin, Yan Li, Qianwei Zhang, Saijun Lin, Zuisu Yang, Guofang Ding   +5 more
doaj   +1 more source

Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]

, 2008
Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T., Ebner, David C., Krishnan, Shyam, Ramtohul, Yeeman K., Stoltz, Brian M., Tambar, Uttam K.   +5 more
core   +2 more sources

Asymmetric α‐Alkylation With Activated and Unactivated Electrophiles by a Highly Productive and Recyclable Lewis Acid/Imidazolium Catalyst

Angewandte Chemie International Edition, EarlyView.
An air‐stable, easily prepared, bifunctional Cu(II)/imidazolium complex enables highly enantioselective α‐alkylation of 1,3‐dicarbonyls with outstanding productivity (TON up to 1740). Highlights include broad electrophile scope spanning π‐activated and nonactivated reagents, stereo‐retentive allylation, simple catalyst synthesis, and efficient catalyst
Johanna Haußmann, Alexander Beck, Dominik Hornung, Michael Mistele, Alexander Allgaier, Wolfgang Frey, Joris van Slageren, Johannes Kästner, René Peters   +8 more
wiley   +1 more source

Enantioselective [3 + 2] annulation of α-substituted allenoates with β,γ-unsaturated N-sulfonylimines catalyzed by a bifunctional dipeptide phosphine

Beilstein Journal of Organic Chemistry, 2016
The first enantioselective [3 + 2] annulation of α-substituted allenoates with β,γ-unsaturated N-sulfonylimines is described. In the presence of a dipeptide phosphine catalyst, a wide range of highly functionalized cyclopentenes bearing an all-carbon ...
Huanzhen Ni, Weijun Yao, Yixin Lu
doaj   +1 more source

Enantioselective Hydrogenation of Ketopantolactone

Journal of Catalysis, 1997
The enantioselective hydrogenation of ketopantolactone toR-(−)-pantolactone was investigated on 5 wt% Pt/Al2O3chirally modified with cinchonidine. The influence of catalyst pretreatment conditions, hydrogen pressure, temperature, solvent polarity, and catalyst, reactant, and modifier concentrations was studied in a slurry reactor.
Schürch, Markus, Schwalm, Olivier, Mallat, T., Weber, Jacques, Baiker, Alfons   +4 more
openaire   +2 more sources

Asymmetric organocatalysis of the addition of acetone to 2-nitrostyrene using N-diphenylphosphinyl-1,2-diphenylethane-1,2-diamine (PODPEN) [PDF]

, 2010
The highly enantioselective addition of acetone to 2-nitrostyrene, using N–diphenylphosphinyl-trans-1,2-diphenylethane-1,2-diamine (PODPEN) as catalyst, is ...
A. Simon Partridge, Bernardi, Burns, Charles V. Manville, Chaun, Connon, Dahlin, Daugidas T. Racys, David J. Morris, Denmark, Eder, Fletcher, García-García, Gary Woodward, Gordon Docherty, Hayashi, Hine, Hine, Huang, Ju, Kohmura, Laars, Lattanzi, Li, Liu, Liu, Martin Wills, Massi, Mei, Melchiorre, Ni, Ni, Pansare, Rishel, Seayad, Sulzer-Mosse, Suzuki, Tan, Tan, Tan, Tsandi, Tsogeova, Vijaikumar, Wang, Wang, Wang, Watson, Xu, Xu, Xu, Xu, Xue, Yu, Zhang   +53 more
core   +1 more source