Results 201 to 210 of about 119,652 (298)

Enantioselective Synthesis of Spirolactones and Spirolactams Under Low Catalyst Loadings. [PDF]

J Am Chem Soc
Saito T, Navarro A, Davies HML.
europepmc   +1 more source

Memory of Chirality in Radical Addition–Translocation–Cyclization Cascades

Helvetica Chimica Acta, Volume 109, Issue 5, May 2026.
Radical addition–translocation–cyclization cascades of chiral alkynes show striking memory of chirality (MoC), with strong retention of configuration when fast, polarity favored cyclization are involved. The most effective system employs a highly electron‐poor pentafluorobenzenesulfonyl group.
Christian Simon Gloor, Fabrice Dénès, Valentin Soulard, Philippe Renaud   +3 more
wiley   +1 more source

Copper-catalyzed atroposelective hydroarylation of 1-alkynylindoles. [PDF]

Nat Commun
Xu HJ, Chen CM, Zhang Z, Ye LW, Zhou B.
europepmc   +1 more source

Rhodium‐Catalyzed Regioselective Addition of N‐Hydroxyl Imides to Internal Alkynes

Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.
An intermolecular rhodium‐catalyzed regioselective addition of N‐hydroxyl imides to internal alkynes leads to branched O‐allyl compounds, which can be readily transformed to allylic alcohols and O‐allyl hydroxylamines after deprotection. Isotopic labelling experiments suggest a plausible reaction mechanism.
Zi Liu, Bernhard Breit
wiley   +1 more source

Asymmetric Hydrogen Atom Transfer. [PDF]

ACS Catal
Feng AG, Pinto Pereira Junior MV, Miller SJ, Knowles RR.   +3 more
europepmc   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

NHC-catalyzed asymmetric synthesis of natural products and pharmaceutical drugs. [PDF]

RSC Adv
Shahid A, Khan SG, Saif MJ, Zahoor AF, Parveen B, Mushtaq A, Mansha A, Mermer A, Chaudhry AR, Irfan A.   +9 more
europepmc   +1 more source

Insights Into Bifenthrin Stereoisomers and Their Regulatory Implications

ChemistryOpen, Volume 15, Issue 5, May 2026.
Bifenthrin is a pyrethroid insecticide with two stereogenic centers, generating four stereoisomers with distinct physicochemical and electronic properties. A combined crystallographic and density functional theory study, supported by Hirshfeld surface, quantum theory of atoms in molecules, natural bond orbital, and reactivity descriptor analyses ...
Nayara C. M. Santos, Nayara D. Coutinho, Vitor S. Duarte, Anderson Catao, Antônio S. N. Aguiar, Lucas D. Dias, James O. Fajemiroye, Hamilton B. Napolitano   +7 more
wiley   +1 more source