Results 221 to 230 of about 119,652 (298)

Two‐Step Synthesis of a Chiral Fluorinated Alcohol With Silica‐Supported Enzyme RrADH in Batch and Continuous Flow Mode

Chemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.
A two‐step process was transferred from batch to flow mode for the synthesis of (R)‐2‐fluoro‐1‐phenylethanol as a benchmark, consisting of a decarboxylative fluorination in aqueous media, followed by an enantioselective biocatalytic reduction of the prochiral intermediate with RrADH immobilized on silica supraparticles.
Egzon Cermjani, Greta Nölke, Stefano Di Fiore, Christoph Deckers, Doris Hanselmann, Bettina Herbig, Susanne Wintzheimer, Thomas H. Rehm   +7 more
wiley   +1 more source

Neue und verbesserte organokatalytische Aldolreaktionen [PDF]

, 2011
Zumbansen, Kristina
core  

Intermolecular Enantioselective Nickel-Catalyzed Arylation of Un-Activated C(sp³)─H Bond. [PDF]

Angew Chem Int Ed Engl
Brunard E, Huang F, Díaz-Jiménez À, Kostiukovska S, Wencel-Delord J.   +4 more
europepmc   +1 more source

Stereoselective Chemoenzymatic Synthesis Metaraminol Involving Gold‐Catalysed Alkyne Hydration and Carbonyl Biotransamination

European Journal of Organic Chemistry, Volume 29, Issue 16, 25 April 2026.
A chemoenzymatic synthesis of (1R,2S)‐metaraminol was developed by combining gold(I)‐catalysed alkyne hydration and stereoselective biotransamination in a sequential one‐pot process. Various phenol protection strategies were considered in oxidation‐reduction sequences, providing access to enantiopure propargylic alcohols as starting materials for ...
Lorena Escot, Iván Lavandera, Vicente Gotor‐Fernández   +2 more
wiley   +1 more source

Author Correction: Enantioselective construction of inherently chiral pillar[5]arenes via palladium-catalysed Suzuki-Miyaura cross-coupling. [PDF]

Nat Commun
Luan TR, Sun C, Tian YL, Jiang YK, Xi LL, Liu RR.   +5 more
europepmc   +1 more source

Enantioselectivity in Transition Metal Catalyzed Propargylic Substitution Reactions: A Theoretical Perspective

Chemistry – A European Journal, Volume 32, Issue 15, 22 April 2026.
Recent theoretical efforts to elucidate the origin of enantioselectivity in transition metal‐catalyzed propargylic substitution reactions are highlighted in this review. ABSTRACT In recent years, asymmetric catalytic propargylic substitution reactions have undergone remarkable development, enabling the construction of chiral carbon centers adjacent to ...
Ken Sakata, Yoshiaki Nishibayashi
wiley   +1 more source

Asymmetric synthesis of planar-chiral metacyclophanes <i>via</i> aromatic amination enabled enantioselective desymmetrization. [PDF]

Chem Sci
Zhou C, Zhou J, Zhang L, Xie W, Gu H, Liu H, Yang X.   +6 more
europepmc   +1 more source

Lipase–V‐MPS Co‐Catalyzed Dynamic Kinetic Resolution of Tertiary Alcohols: Process Intensification Through Catalyst Compartmentalization

European Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.
Dynamic kinetic resolution of tert‐alcohols co‐catalyzed by lipase and V‐MPS4 is reported, enabled by compartmentalization using a polydimethylsiloxane thimble. Physical separation of V‐MPS4 from lipase and Na2CO3 was crucial for preserving its racemization activity.
Satoshi Horino, Karla Wagner, Anke Hummel, Kyohei Kanomata, Harald Gröger, Shuji Akai   +5 more
wiley   +1 more source

Enantioselective Synthesis of 3-Alkyl-1,5-Functionalized 1,4-Diynes via Isoxazol-5(4<i>H</i>)-ones. [PDF]

Org Lett
Torán R, Vercher S, López P, Sanz-Marco A, Montesinos-Magraner M, Vila C, Blay G.   +6 more
europepmc   +1 more source

Silyl Rearrangements in Gold‐Catalyzed Transformations

European Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.
The synergy between the exceptional ability of gold catalysts to activate unsaturated substrates and the inherent tendency of organosilicon reagents to undergo silyl‐group rearrangements has unlocked a range of novel transformations, enabling access to otherwise challenging molecular architectures.
Patricia García‐Martínez, Luis A. López   +1 more
wiley   +1 more source