Enantioselective Synthesis of Sealutomicin C. [PDF]
J Am Chem SocThe sealutomicins are a family of anthraquinone antibiotics featuring an enediyne (sealutomicin A) or Bergman-cyclized aromatic ring (sealutomicins B–D).
Astle SM +6 more
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Enantioselective synthesis of chiroplasmonic helicoidal nanoparticles by nanoconfinement in chiral dielectric shells [PDF]
Nature CommunicationsHelicoid metal nanoparticles with intrinsic chirality have unveiled tailorable properties and unlocked many chirality-related applications across various fields.
Xiaoxi Luan +10 more
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Organocatalytic enantioselective synthesis of double S-shaped quadruple helicene-like molecules [PDF]
Nature CommunicationsHelicene-shaped molecules are compelling chemical structures with unique twisted helical chirality and remarkable properties. Although progress occurs in the catalytic asymmetric synthesis of helicene (-like) molecules, the enantioselective synthesis of ...
Shengli Huang +7 more
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Enantioselective Synthesis of Oxazocines via MQ‐Phos Enabled Palladium‐Catalyzed Asymmetric Formal [4+4]‐Cycloadditions [PDF]
Advanced ScienceOxazocines are key structural intermediates in the synthesis of natural products and pharmaceutical molecules. However, the synthesis of oxazocines especially in a highly enantioselective manner, is a long‐standing formidable challenge due to unfavorable
Qiaojing Meng +6 more
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Chemical Reviews, 2021 Chiral amines are key structural motifs present in a wide variety of natural products, drugs, and other biologically active compounds. During the past decade, significant advances have been made with respect to the enantioselective synthesis of chiral ...
Albert Cabré, X. Verdaguer, A. Riera
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On the Origins of Life's Homochirality: Inducing Enantiomeric Excess with Spin-Polarized Electrons [PDF]
Proc. Natl. Acad. Sci. U.S.A. 119 (2022), 2022 Life as we know it is homochiral, but the origins of biological homochirality on early Earth remain elusive. Shallow closed-basin lakes are a plausible prebiotic environment on early Earth, and most are expected to have significant sedimentary magnetite deposits.
arxiv +1 more source
Enantioselective chiral orientation induced by a combination of a long and a short laser pulse [PDF]
Phys. Rev. A 105, 033113 (2022), 2021 Enantioselective orientation of chiral molecules excited by a shaped picosecond laser pulse and a delayed femtosecond pulse is considered. Using quantum mechanical simulations, we demonstrate a strong field-free enantioselective orientation along the laser propagation direction.
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Optimal Selective Orientation of Chiral Molecules Using Femtosecond Laser Pulses [PDF]
J. Chem. Phys. 157, 034304 (2022), 2022 We present a comprehensive study of enantioselective orientation of chiral molecules excited by a pair of delayed cross-polarized femtosecond laser pulses. We show that by optimizing the pulses' parameters, a significant (~ 10%) degree of enantioselective orientation can be achieved at zero and at five kelvin rotational temperatures.
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Synthesis of achiral rod-shaped triazolic molecules and investigation of their striped texture and propeller-patterned nematic droplets [PDF]
Liquid Crystals 50, 1324 (2023), 2023 In this study, novel achiral mesogens containing 4,4'-biphenyl central core connected on both sides through an ester function to 1-(4-(alkyloxy)phenyl)-1H-[1,2,3]-triazolyl group have been synthesized and characterized. Different mesophases have been identified, with the appearance of both a periodic striped pattern and propeller-patterned droplets ...
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Nature Communications, 2023 The primary objective in synthetic organic chemistry is to develop highly efficient, selective, and versatile synthetic methodologies, which are essential for discovering new drug candidates and agrochemicals. In this study, we present a unified strategy
Fang-Fang Xu +3 more
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