Results 1 to 10 of about 83,738 (273)

Enantioselective Synthesis of a New Non-Natural Gabosine [PDF]

Molecules, 2021
The preparation of a new non-natural gabosine is reported, in which the chirality is transferred from the toluene’s biotransformed metabolite (1R,2S)-3-methylcyclohexa-3.5-diene-1,2-diol.
Maximiliano Colobbio, Enrique Pandolfi, Valeria Schapiro   +2 more
doaj   +2 more sources

Enantioselective synthesis of chiroplasmonic helicoidal nanoparticles by nanoconfinement in chiral dielectric shells [PDF]

Nature Communications
Helicoid metal nanoparticles with intrinsic chirality have unveiled tailorable properties and unlocked many chirality-related applications across various fields.
Xiaoxi Luan, Yu Tian, Fengxia Wu, Lu Cheng, Minghua Tang, Xiali Lv, Haili Wei, Xiaodan Wang, Fenghua Li, Guobao Xu, Wenxin Niu   +10 more
doaj   +2 more sources

Catalytic enantioselective synthesis of selenium-containing atropisomers via C–Se bond formations [PDF]

Beilstein Journal of Organic Chemistry
Atropisomers are not only prevalent in biologically active natural products and pharmaceuticals, but they have also garnered increasing attention for their effectiveness as ligands and catalysts in the field of catalytic asymmetric synthesis.
Qi-Sen Gao, Zheng-Wei Wei, Zhi-Min Chen
doaj   +2 more sources

Photoenzymatic enantioselective synthesis of fluorinated amides with remote stereocenter [PDF]

Nature Communications
Fluorinated compounds are scarce in nature, albeit they are in high demand in pharmaceuticals, agrochemicals, and materials. Fluorinated amides serve as prevalent structural motifs in pharmaceuticals and bioactive molecules.
Chaoqun Huang, Xuerui Jin, Zhenyu Liu, Can Cui, Yang Zhang, Binju Wang, Chun Zhang, Jianqiang Feng, Dawen Niu, Yunzi Luo   +9 more
doaj   +2 more sources

Rhodium-Catalyzed Allylic Amination for the Enantioselective Synthesis of Tertiary β-Fluoroamines. [PDF]

Org Lett
Chukwu FO, Arachchi MK, Nguyen HM.
europepmc   +3 more sources

Enantioselective [4+2] Annulation to the Concise Synthesis of Chiral Dihydrocarbazoles

iScience, 2020
Summary: A highly efficient phosphine-catalyzed enantioselective [4 + 2] annulation of allenoates with 3-nitroindoles or 3-nitrobenzothiophenes has been developed.
Haiyang Wang, Qingdong Hu, Mingxu Wang, Chang Guo   +3 more
doaj   +1 more source

Catalytic enantioselective reductive alkynylation of amides enables one-pot syntheses of pyrrolidine, piperidine and indolizidine alkaloids

Nature Communications, 2023
The primary objective in synthetic organic chemistry is to develop highly efficient, selective, and versatile synthetic methodologies, which are essential for discovering new drug candidates and agrochemicals. In this study, we present a unified strategy
Fang-Fang Xu, Jin-Quan Chen, Dong-Yang Shao, Pei-Qiang Huang   +3 more
doaj   +1 more source

Challenging Atroposelective C–H Arylation

SynOpen, 2020
Atropisomeric molecules are privileged scaffolds, not only as ligands for asymmetric synthesis, but also as biologically active products and advanced materials.
Joanna Wencel-Delord, Françoise Colobert   +1 more
doaj   +1 more source

Atropselective syntheses of (-) and (+) rugulotrosin A utilizing point-to-axial chirality transfer [PDF]

, 2015
Chiral, dimeric natural products containing complex structures and interesting biological properties have inspired chemists and biologists for decades.
A Zask, Anne C. Meister, B Franck, BB Liau, BH Lipshutz, CA Broka, CE Müller, CF Nising, DA Evans, F Guo, G Bringmann, G Bringmann, G Xu, GA Molander, GP Moss, H Kikuchi, H Kikuchi, J Clayden, JM Wilson, John A. Porco, K-S Masters, KC Nicolaou, LC Konkol, LF Tietze, LF Tietze, LF Tietze, M Stewart, MC Kozlowski, NC Bruno, NZ Burns, PS Steyn, R Martin, Richard P. Johnson, Robert J. Capon, RS Coleman, S Huang, S Little, S Masamune, Sarah L. Skraba-Joiner, SR LaPlante, T Gensch, T Hamada, T Qin, T Qin, T Wezeman, TE Barder, Tian Qin, VB Birman, W Tang, X Shen, Y Zhou, Y Zhou, YS Park, Zeinab G. Khalil   +53 more
core   +5 more sources

Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids [PDF]

, 2007
Herein, we report the automated parallel synthesis of solution-phase libraries of phosphoramidite ligands for the development of enantioselective catalysts.
Feringa, Ben L.,, Jagt, Richard B.C.,, Minnaard, Adriaan J.,, Schudde, Ebe P.,, Toullec, Patrick Y.,, Vries, Johannes G. de,   +5 more
core   +1 more source