Results 111 to 120 of about 3,272,143 (363)

Three‐Component Synthesis of γ‐Amino Esters with α‐Quaternary Carbon Centers via NHC/Photoredox Dual Catalysis

Advanced Synthesis &Catalysis, EarlyView.
γ‐Amino acid derivatives with an α‐quaternary center are prevalent in medicinally important compounds. A dual N‐heterocyclic carbene/photocatalytic pathway is developed for the three‐component synthesis of α, α ‐disubstituted γ‐amino esters. This methodology allows for the rapid synthesis of diverse libraries of γ‐amino esters in good yields.
Adam X. Wayment, Karl A. Scheidt
wiley   +1 more source

Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers.

Journal of the American Chemical Society, 2020
A scalable enantioselective nickel-catalyzed electrochemical reductive homocoupling of aryl bromides has been developed, affording enantioenriched axially chiral biaryls in good yield under mild conditions using electricity as a reductant in an undivided
Hui Qiu, B. Shuai, Yunzhong Wang, Dong Liu, Yue-Gang Chen, Pei‐Sen Gao, Hong-Xing Ma, Song Chen, T. Mei   +8 more
semanticscholar   +1 more source

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

Advanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source

Photocatalytic Enantioselective Radical Cascade Multicomponent Minisci Reaction of β‐Carbolines Using Diazo Compounds as Radical Precursors

Advanced Science
Here, a photocatalytic asymmetric multicomponent cascade Minisci reaction of β‐carbolines with enamides and diazo compounds is reported, enabling an effective enantioselective radical C─H functionalization of β‐carbolines with high yields and ...
Yi‐Jie Gu, Mu‐Peng Luo, Hua Yuan, Guo‐Kai Liu, Shou‐Guo Wang   +4 more
doaj   +1 more source

Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]

, 2016
The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA, Croft, RA, Davis, OA, Doran, R, Morgan, KF   +4 more
core   +1 more source

Super‐Heterostructures of Twisted Pd Nanoarrays Epitaxially Grown on Chiral Au Nanorods Boost Circularly Polarized Photocatalysis

Advanced Science, EarlyView.
Au‐Pd super‐heterostructures not only retard the damping of chiroptical response but also enantio‐selectively enhance photocatalysis, thanks to the chiral electromagnetic field and chiral hot electrons. Abstract Seed‐mediated growth provides an efficient way to produce chiral hybrid nanocrystals, mainly benefitting from the recent successful synthesis ...
Taotao Luo, Haoyu Li, Zhicheng Zhang, Shenli Wang, Xiaobin Pan, Stefanos Mourdikoudis, Chao Xue, Junjun Li, Kwok‐Yin Wong, Guangchao Zheng   +9 more
wiley   +1 more source

Nine-Membered Benzofuran-Fused Heterocycles: Enantioselective Synthesis by Pd-Catalysis and Rearrangement via Transannular Bond Formation.

Journal of the American Chemical Society, 2017
The first enantioselective formal [5+4] cycloaddition is realized under palladium catalysis to deliver benzofuran-fused nine-membered rings. These medium-sized heterocycles and derivatives undergo unique rearrangements induced by transannular bond ...
Zi-Qiang Rong, Li-Cheng Yang, Song Liu, Zhaoyuan Yu, Ya-Nong Wang, Zher Yin Tan, Rui-Zhi Huang, Y. Lan, Yu Zhao   +8 more
semanticscholar   +1 more source

Symmetry Breaking of Molecules Triggered by Chiral Inorganic Nanostructures Without Organic Components

Advanced Science, EarlyView.
Chiral nano‐inorganics, free of organic chiral ligands, provide a novel platform to direct symmetry breaking in molecular systems, through inorganic‐to‐organic chirality transfer via enantiospecific inorganic–organic interactions, circularly polarized light, and electron spin‐driven enantiopreferential reactions governed by chiral‐induced spin ...
Tao Yao, Xiao Chen, Yating Fang, Zhifeng Huang   +3 more
wiley   +1 more source

Nickel(II)/BINOL-catalyzed enantioselective C–H activation via desymmetrization and kinetic resolution

Nature Communications
The field of nickel catalysis has witnessed remarkable growth in recent years. However, the use of nickel catalysts in enantioselective C–H activation remains a daunting challenge because of their variable oxidation states, intricate coordination ...
Qi-Jun Yao, Fan-Rui Huang, Jia-Hao Chen, Bing-Feng Shi   +3 more
doaj   +1 more source

Enantioselective synthesis of aziridines using asymmetric transfer hydrogenation as a precursor for chiral derivatives used as bonding agent for rocket solid propellants

Química Nova, 2002
A rapid, expedient and enantioselective method for the synthesis of beta-hydroxy amines and monosubstituted aziridines in up to 99% e.e., via asymmetric transfer hydrogenation of a-amino ketones and cyclisation through treatment with tosyl chloride and ...
Aparecida M. Kawamoto, Martin Wills
doaj   +1 more source