Results 131 to 140 of about 3,273,294 (390)
Enantioselective Total Synthesis of (‐)‐Xialenon A.
ChemInform, 2002 AbstractFor Abstract see ChemInform Abstract in Full Text.
Hodgson, D, Galano, J, Christlieb, M
openaire +4 more sources
Enantioselective Total Synthesis of (+)‐Obtusenyne. [PDF]
ChemInform, 2003 A total synthesis of the laurencia metabolite (+)-obtusenyne has been completed. The key steps include a Sharpless kinetic resolution and an asymmetric glycolate alkylation to establish the stereogenic centers adjacent to the ether linkage and a ring-closing metathesis reaction to construct the nine-membered ether without the aid of a cyclic ...
Mark T. Powell, Michael T. Crimmins
openaire +4 more sources
Design, Synthesis, and Application of Immobilized Enzymes on Artificial Porous Materials
Advanced Science, EarlyView.This review comprehensively summarizes the advances in research for immobilized enzymes on artificial porous materials. It highlights the advantages of bottom‐up strategy, post‐synthesis modification and composite method of metal‐organic frameworks (MOFs), covalent organic frameworks (COFs) and hydrogen‐bonded organic frameworks (HOFs) and emphasizes ...
Lu Ran +4 more
wiley +1 more source
Engineered Biocatalyst for Enantioselective Hydrazone Reduction
Angewandte Chemie, EarlyView.Here, we report the discovery and engineering of a hydrazone reductase (HRED) biocatalyst that promotes efficient reduction of protected hydrazones with exceptional stereocontrol. These biotransformations offer a sustainable strategy for synthesizing valuable chiral N─N containing products that are commonly found in pharmaceuticals and agrochemicals ...
Amy E. Hutton +9 more
wiley +2 more sources
Beilstein Journal of Organic Chemistry, 2014 Pd-catalyzed enantioselective alkylation in conjunction with further synthetic elaboration enables the formal total syntheses of a number of “classic” natural product target molecules. This publication highlights recent methods for setting quaternary and
Yiyang Liu +11 more
doaj +1 more source
Short Enantioselective Formal Synthesis of (–)-Platencin [PDF]
, 2018 A short enantioselective formal synthesis of the antibiotic natural product platencin is reported. Key steps in the synthesis include enantioselective decarboxylation alkylation, aldehyde/olefin radical cyclization, and regioselective aldol ...
Defieber, Christian +3 more
core
Oxidative Heck desymmetrisation of 2,2-disubstituted cyclopentene-1,3-diones [PDF]
, 2015 Oxidative Heck couplings have been successfully developed for 2,2-disubstituted cyclopentene-1,3-diones. The direct coupling onto the 2,2-disubstituted cyclopentene-1,3-dione core provides a novel expedient way of enantioselectively desymmetrising all ...
Beattie, N. A. +4 more
core +1 more source
Advanced Science, EarlyView.Au‐Pd super‐heterostructures not only retard the damping of chiroptical response but also enantio‐selectively enhance photocatalysis, thanks to the chiral electromagnetic field and chiral hot electrons. Abstract Seed‐mediated growth provides an efficient way to produce chiral hybrid nanocrystals, mainly benefitting from the recent successful synthesis ...
Taotao Luo +9 more
wiley +1 more source
Angewandte Chemie, EarlyView.Topologically unique, 3D cage‐like noradamantanes are synthesized in one pot from simple starting materials. Catalyzed by diphenylprolinol silyl ether, the reaction followed a domino sequence of Michael/epimerization/Michael/1,2‐addition, achieving excellent enantioselectivity.
Konstantinos Daskalakis +6 more
wiley +2 more sources
Journal of the American Chemical Society, 2017 The first enantioselective formal [5+4] cycloaddition is realized under palladium catalysis to deliver benzofuran-fused nine-membered rings. These medium-sized heterocycles and derivatives undergo unique rearrangements induced by transannular bond ...
Zi-Qiang Rong +8 more
semanticscholar +1 more source