Results 131 to 140 of about 3,272,143 (363)

Interfacial Coordination Induced Crystalline Metallacyclic Membrane for High‐Performance Enantioseparation

Aggregate, EarlyView.
A chiral crystalline metallacyclic membrane is developed via an interfacial coordination self‐assembly of organic and metallic ligands. The ordered metallacyclic membrane exhibits exceptional enantioseparation for racemic mixtures with ultra‐high enantioselectivity (up to 100% enantiomeric excess value) and enhanced permeance.
Run‐Hao Li, Yumei Wang, Yi Liu, Yue Sun   +3 more
wiley   +1 more source

Unlocking Lactonase Enzymes as Biocatalysts for the Deracemisation of Chiral γ‐Thiolactones

Angewandte Chemie, EarlyView.
The application of lactonase enzymes as biocatalysts still remains underexplored. This study discloses the biocatalytic activity of two lactonases in the deracemisation of chiral C3‐substituted‐γ‐thiolactones. The biocatalyst GcL catalyses the enzymatic kinetic resolution (EKR) of C3‐amide‐thiolactones, while the rationally engineered biocatalyst N9 ...
Jingyue Wu, Michele Crotti, Ivan Bassanini, Mahdi Hassankalhori, Erica Elisa Ferrandi, Ferran Sancho, Daniela Monti, Daniele Castagnolo   +7 more
wiley   +2 more sources

Enantioselective Synthesis of Cyclobutylboronates via a Copper-Catalyzed Desymmetrization Approach.

Angewandte Chemie, 2016
The first catalytic enantioselective synthesis of cyclobutylboronates, by using a chiral copper(I) complex, is reported. A broad variety of cyclobutanes have been prepared with consistently high levels of diastereo- and enantiocontrol.
Manuel Guisán-Ceinos, A. Parra, Víctor Martín-Heras, M. Tortosa   +3 more
semanticscholar   +1 more source

Synthesis of a BINOL‐Derived Sulfide Catalyst Bearing a Diphenylmethanol Unit and Its Application in Asymmetric Bromolactonizations

Asian Journal of Organic Chemistry, EarlyView.
The excellent catalytic performance of a BINOL‐derived sulfide catalyst bearing a diphenylmethanol unit was demonstrated in the highly enantioselective synthesis of γ‐butyrolactones via bromolactonization. Abstract A BINOL‐derived sulfide catalyst bearing a diphenylmethanol unit was prepared.
Yasuaki Furuya, Ryuichi Nishiyori, Seiji Shirakawa   +2 more
wiley   +1 more source

Cooperative Photometallobiocatalysis: Nonheme Fe Enzyme‐Catalyzed Enantioconvergent Radical Decarboxylative Azidation, Thiocyanation, and Isocyanation of Redox‐Active Esters

Angewandte Chemie, EarlyView.
Through the directed evolution of an underexploited nonheme Fe extradiol dioxygenase, we developed a unified cooperative photobiocatalytic strategy to allow for three types of enantioconvergent radical transformations, including azidation, thiocyanation, and isocyanation.
Liu‐Peng Zhao, Ken Lin, Pei‐Pei Xie, Huichong Liu, Hengye Xiang, Xin Liu, Yunlong Zhao, Peng Liu, Yang Yang   +8 more
wiley   +2 more sources

Stereoselective total synthesis and enantioselective formal synthesis of the antineoplastic sesquiterpene quinone metachromin A

Journal of the Brazilian Chemical Society, 1999
The first total synthesis of the antineoplastic marine natural product metachromin-A (1) was accomplished through a convergent synthetic approach amenable to the preparation of analogues for biological studies.
Almeida Wanda P., Correia Carlos Roque D.   +1 more
doaj  

Enantioselective synthesis of (R)‐ and (S)‐2‐methyl‐[3,3,2‐2H3] alanines [PDF]

, 1986
Pullachipatti K. Subramanian, Ronald W. Woodard   +1 more
openalex   +1 more source

Enantioselective Total Synthesis of (−)‐Diversonol

Chemistry – A European Journal, 2013
AbstractFor the synthesis of (−)‐diversonol (ent‐1), an enantioselective domino‐Wacker/carbonylation/methoxylation reaction and an enantioselective Wacker oxidation were used to give the chroman in high yield and 96 % and 93 % ee, respectively. Dihydroxylation at the vinyl moiety using the Sharpless procedure and a Wittig–Horner reaction followed by ...
Tietze, Lutz Friedjan, Jackenkroll, Stefan, Raith, Christian, Spiegl, Dirk A., Reiner, Johannes R., Campos, Maria Claudia Ochoa   +5 more
openaire   +4 more sources

Solvent‐Directed Handedness in a Chirally Twisted Tetrakisporphyrin Macrocycle

Asian Journal of Organic Chemistry, EarlyView.
A chirally twisted tetrakisporphyrin macrocycle was synthesized by incorporating a chiral dioxolane into a tetrakisporphyrin macrocycle. The solvent type influenced the preferred handedness of the twisted conformation. Circular dichroism measurements and computational analyses determined the handedness of the conformers in solvents toluene and ...
Kouta Tanabe, Naoyuki Hisano, Takeharu Haino   +2 more
wiley   +1 more source

Stereocontrol in Conformationally Stable C(sp2)─C(sp3) Atropisomers

Angewandte Chemie, EarlyView.
Building in our expertize in the synthesis of trans‐dihydrobenzofurans via organocatalyzed domino Michael/O‐cyclization between β‐naphthols and nitroalkenes, we developed an efficient strategy to access a new family of atropisomers bearing a conformationally stable C(sp2)─C(sp3) bond and two stereogenic centers through simple and highly ...
Antoine Domain, Guishun Bai, Juan‐Carlos Castillo, Hassane Moussa Abdraman, Stéphane Humbel, Michel Giorgi, Jean‐Valère Naubron, Sara Chentouf, Jean Rodriguez, Xiaoze Bao, Damien Bonne   +10 more
wiley   +2 more sources