Results 141 to 150 of about 83,738 (273)
Enantioselective Total Synthesis of Tricyclic Myrmicarin Alkaloids
Mohammad Movassaghi, Alison E. Ondrus
openalex +1 more source
Intramolecular Carbolithiation of Allyl o‐Lithioaryl Ethers: A New Enantioselective Synthesis of Functionalized 2,3‐Dihydrobenzofurans [PDF]
José Barluenga +3 more
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Marine polyhydroxylated macrolides’ drug discovery potential is limited by structural complexity and scarce material supply, hindering structure assignment, synthesis, and biological studies. Here, we present an integrated workflow that combines chemogenomic profiling, ultra‐high‐resolution NMR‐guided structural revision and stereochemical assignment ...
Malcolm R. P. George +9 more
wiley +1 more source
Enantioselective Total Synthesis of Otteliones A and B, Novel and Powerful Antitumor Agents from the Freshwater Plant Ottelia alismoides [PDF]
Tadashi Katoh
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The first catalytic and metal‐free enantioselective synthesis of (–)‐arnottin II is reported. A one‐pot hydrolysis/oxidative spirolactonization sequence, catalyzed by a chiral hypervalent iodine(I/III) complex under phosphate‐buffered conditions, establishes efficient control of the unstable biaryl hydroxy carboxylic acid (BHCA) intermediate, to afford
Kirara Saeda +2 more
wiley +1 more source
A borrowing hydrogen strategy using an NHC‐Ir(III) catalyst enables selective N‐functionalization of unprotected amino sugars using alcohols as alkylating agents. The use of unprotected substrates avoids extra steps of protection/deprotection, minimizing waste generation.
Aitor Bermejo‐López +7 more
wiley +1 more source

