Results 11 to 20 of about 83,738 (273)

Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis [PDF]

, 2014
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is reported. The key step of this synthesis is a cascade metathesis reaction, which leads in one operation to the required tricycle if appropriate fine-tuning ...
Aldegunde M. J., Aldegunde M. J., Aldegunde M. J., Aurélien Letort, Bourgeois D., Bourgeois D., Bourgeois D., Bourgeois D., Bourgeois D., Chatterjee A. K., Cong Ma, De-Liang Long, Doi T., Garber S. B., Goldring P. D., Grieco P. A., Holton R. A., Holton R. A., Joëlle Prunet, Kim S.-H., Ma C., Masters J. J., Mendoza A., Morihara K., Mukaiyama T., Muller B., Muller B., Nicolaou K. C., Rémi Aouzal, Schiltz S., Scholl M., Schwab P., Swindell C. S., Wender P. A., Wender P. A., Wilde N. C., Winkler J. D., Yamazaki Y., Yared J. A., Yvon D.   +39 more
core   +3 more sources

Ferrocene-derived P,N ligands : synthesis and application in enantioselective catalysis [PDF]

, 2013
Due to their unique steric and electronic properties, air-stability and modular structure, chiral hybrid P,N-ferrocenyl ligands play a prominent role in the field of asymmetric catalysis.
Noël, Timothy, Van der Eycken, Johan
core   +1 more source

Alilação e crotilação catalítica e enantiosseletiva de aldeídos

Química Nova, 2006
The field of chiral catalysis has experienced explosive growth over the last two decades. By now, many of the classical reactions in organic synthesis can be carried out efficiently in asymmetric manner.
Ângelo de Fátima, Luís Gustavo Robello, Ronaldo Aloise Pilli   +2 more
doaj   +3 more sources

Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]

, 2008
Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T., Ebner, David C., Krishnan, Shyam, Ramtohul, Yeeman K., Stoltz, Brian M., Tambar, Uttam K.   +5 more
core   +2 more sources

Organocatalytic enantioselective synthesis of double S-shaped quadruple helicene-like molecules. [PDF]

Nat Commun
Huang S, Wen H, Li Y, Qin W, Wang P, Lan Y, Jia S, Yan H.   +7 more
europepmc   +3 more sources

Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]

, 2016
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima, Lassaletta, José M., Matador Martínez, Esteban, Monge Fernández, David, Retamosa Hernández, María Gracia   +4 more
core   +1 more source

Biologically active Phytophthora mating hormone prepared by catalytic asymmetric total synthesis [PDF]

, 2008
A Phytophthora mating hormone with an array of 1,5-stereogenic centers has been synthesized by using our recently developed methodology of catalytic enantioselective conjugate addition of Grignard reagents. We applied this methodology in a diastereo- and
A. J. Minnaard, B. L. Feringa, Bajpai, Des Mazery, F. Govers, Fabritius, Govers, Harutyunyan, Howell, Judelson, Judelson, K. Bouwmeester, Lamour, Lopez, L  pez, Moreau, Qi, Randall, S. R. Harutyunyan, Smith, T. d. Hartog, van der Lee, van Summeren, Z. Zhao   +23 more
core   +4 more sources

Enantioselective Copper-Catalyzed Cyanation of Remote C(sp3)-H Bonds Enabled by 1,5-Hydrogen Atom Transfer

iScience, 2019
Summary: The direct functionalization of C(sp3)-H bonds has led to the development of methods to access molecules or intermediates from basic chemicals in an atom- and step-economic fashion.
Cheng-Yu Wang, Zi-Yang Qin, Yu-Ling Huang, Ruo-Xing Jin, Quan Lan, Xi-Sheng Wang   +5 more
doaj   +1 more source

Phosphoramidite Gold(I)-Catalyzed Diastereo- and Enantioselective Synthesis of 3,4-Substituted Pyrrolidines [PDF]

, 2011
In this article the utility of phosphoramidite ligands in enantioselective AuI catalysis was explored in the development of highly diastereo- and enantioselective AuI-catalyzed cycloadditions of allenenes.
Benitez, Diego, Goddard, William A., III, González, Ana Z., Tkatchouk, Ekaterina, Toste, F. Dean   +4 more
core   +3 more sources

Towards stereochemical control: A short formal enantioselective total synthesis of pumiliotoxins 251D and 237A

Beilstein Journal of Organic Chemistry, 2013
A concise enantioselective synthesis of the advanced intermediate 5 for the synthesis of pumiliotoxins (Gallagher’s intermediate) is described. The synthesis started from the regio- and trans-diastereoselective (dr = 98:2) reductive 3-butenylation of (R)-
Jie Zhang, Hong-Kui Zhang, Pei-Qiang Huang   +2 more
doaj   +1 more source