Results 11 to 20 of about 103,462 (210)

Stereocontrolled enantioselective total synthesis of the [2+2] quadrigemine alkaloids. [PDF]

, 2015
A unified strategy for enantioselective total synthesis of all stereoisomers of the 2+2 family of quadrigemine alkaloids is reported. In this approach, two enantioselective intramolecular Heck reactions are carried out at the same time on precursors ...
Canham, Stephen M, Hafensteiner, Benjamin D, Lebsack, Alec D, May-Dracka, Tricia L, Nam, Sangkil, Overman, Larry E, Stearns, Brian A   +6 more
core   +4 more sources

Atropselective syntheses of (-) and (+) rugulotrosin A utilizing point-to-axial chirality transfer [PDF]

, 2015
Chiral, dimeric natural products containing complex structures and interesting biological properties have inspired chemists and biologists for decades.
A Zask, Anne C. Meister, B Franck, BB Liau, BH Lipshutz, CA Broka, CE Müller, CF Nising, DA Evans, F Guo, G Bringmann, G Bringmann, G Xu, GA Molander, GP Moss, H Kikuchi, H Kikuchi, J Clayden, JM Wilson, John A. Porco, K-S Masters, KC Nicolaou, LC Konkol, LF Tietze, LF Tietze, LF Tietze, M Stewart, MC Kozlowski, NC Bruno, NZ Burns, PS Steyn, R Martin, Richard P. Johnson, Robert J. Capon, RS Coleman, S Huang, S Little, S Masamune, Sarah L. Skraba-Joiner, SR LaPlante, T Gensch, T Hamada, T Qin, T Qin, T Wezeman, TE Barder, Tian Qin, VB Birman, W Tang, X Shen, Y Zhou, Y Zhou, YS Park, Zeinab G. Khalil   +53 more
core   +8 more sources

Alilação e crotilação catalítica e enantiosseletiva de aldeídos

Química Nova, 2006
The field of chiral catalysis has experienced explosive growth over the last two decades. By now, many of the classical reactions in organic synthesis can be carried out efficiently in asymmetric manner.
Fátima Ângelo de, Robello Luís Gustavo, Pilli Ronaldo Aloise   +2 more
doaj   +3 more sources

Phosphoramidite Gold(I)-Catalyzed Diastereo- and Enantioselective Synthesis of 3,4-Substituted Pyrrolidines [PDF]

, 2011
In this article the utility of phosphoramidite ligands in enantioselective AuI catalysis was explored in the development of highly diastereo- and enantioselective AuI-catalyzed cycloadditions of allenenes.
Benitez, Diego, Goddard, William A., III, González, Ana Z., Tkatchouk, Ekaterina, Toste, F. Dean   +4 more
core   +3 more sources

Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids [PDF]

, 2007
Herein, we report the automated parallel synthesis of solution-phase libraries of phosphoramidite ligands for the development of enantioselective catalysts.
Feringa, Ben L.,, Jagt, Richard B.C.,, Minnaard, Adriaan J.,, Schudde, Ebe P.,, Toullec, Patrick Y.,, Vries, Johannes G. de,   +5 more
core   +1 more source

Enantioenriched α-substituted glutamates/pyroglutamates via enantioselective cyclopropenimine-catalyzed Michael addition of amino ester imines

Beilstein Journal of Organic Chemistry, 2021
A procedure for the enantioselective synthesis of α-substituted glutamates and pyroglutamates via a cyclopropenimine-catalyzed Michael addition of amino ester imines is described.
Zara M. Seibel, Jeffrey S. Bandar, Tristan H. Lambert   +2 more
doaj   +1 more source

Catalytic asymmetric synthesis of the alkaloid (+)-myrtine [PDF]

, 2008
A new protocol for the asymmetric synthesis of trans-2,6-disubstituted-4-piperidones has been developed using a catalytic enantioselective conjugate addition reaction in combination with a diastereoselective lithiation–substitution sequence; an efficient
Adriaan J. Minnaard, Albrow, Alexakis, Alexakis, Anderson, Bach, Back, Beak, Beak, Beak, Beak, Beak, Beak, Beak, Ben L. Feringa, Bennett, Bennett, Berkheij, Bertini Gross, Brooks, Comins, Comins, Comins, Comins, Comins, Comins, Comins, Curtin, d'Augustin, Davis, Dieter, Dieter, Dieter, Dieter, Dieter, Eilitz, Frankel, Fraser, Gallagher, Garcia-Ruiz, Gardette, Gelas-Mialhe, Hoffmann, Houk, Kerrick, King, Leclercq, Liang, Maria Gabriella Pizzuti, Pilli, Pilli, Pineschi, Pàmies, Remuson, Slosse, Slosse, Still, Tawara, Vuagnoux-d'Augustin, Vuagnoux-d'Augustin, Watson, Whisler, Šebesta   +62 more
core   +1 more source

Enantioselective optical gradient forces using 3D structured vortex light [PDF]

, 2021
Here we highlight enantioselective optical gradient forces present in 3D structured optical vortex tweezing systems. One chiral force originates from the circular polarization of the light, while remarkably the other is independent of the input polarization, even occurring for unpolarized light, and is not present in 2D structured light nor propagating
arxiv   +1 more source

Three Dimensional Orientation of Complex Molecules Excited by Two-Color Femtosecond Pulses [PDF]

J. Phys. B: At. Mol. Opt. Phys. 54 164003 (2021), 2021
We study the excitation of asymmetric-top (including chiral) molecules by two-color femtosecond laser pulses. In the cases of non-chiral asymmetric-top molecules excited by an orthogonally polarized two-color pulse, we demonstrate, classically and quantum mechanically, three-dimensional orientation.
arxiv   +1 more source

Highly efficient synthesis of the tricyclic core of Taxol by cascade metathesis [PDF]

, 2014
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is reported. The key step of this synthesis is a cascade metathesis reaction, which leads in one operation to the required tricycle if appropriate fine-tuning ...
Aldegunde M. J., Aldegunde M. J., Aldegunde M. J., Aurélien Letort, Bourgeois D., Bourgeois D., Bourgeois D., Bourgeois D., Bourgeois D., Chatterjee A. K., Cong Ma, De-Liang Long, Doi T., Garber S. B., Goldring P. D., Grieco P. A., Holton R. A., Holton R. A., Joëlle Prunet, Kim S.-H., Ma C., Masters J. J., Mendoza A., Morihara K., Mukaiyama T., Muller B., Muller B., Nicolaou K. C., Rémi Aouzal, Schiltz S., Scholl M., Schwab P., Swindell C. S., Wender P. A., Wender P. A., Wilde N. C., Winkler J. D., Yamazaki Y., Yared J. A., Yvon D.   +39 more
core   +3 more sources