Results 201 to 210 of about 3,272,143 (363)

Total Synthesis and Structural Revision of (‐)‐Sodagnitin E

Angewandte Chemie International Edition, Accepted Article.
We report the total synthesis of malabaricane triterpene sodagnitin E, marking the first synthesis of any malabaricane natural product to date. The enantioselective synthesis of two key fragments, followed by their coupling via a Mukaiyama aldol reaction delivered the triterpene framework in a convergent synthesis.
Philipp Schoch, Tanja Gaich
wiley   +1 more source

Enantioselective Synthesis of (-)-Vertinolide.

, 1997
Keizo Matsuo, Yusuke Sakaguchi
openalex   +2 more sources

Synthesis and Enantioselectivity of the Antiviral Effects of (R,Z)-,(S,Z)-methylenecyclopropane Analogues of Purine Nucleosides and Phosphoralaninate Prodrugs: Influence of Heterocyclic Base, Type of Virus and Host Cells [PDF]

, 2000
Y-L Qiu, Fiona Geiser, Toshihiko Kira, E Gullen, Y C Cheng, RG Ptak, J BREITENBACH, JC Drach, CB Hartline, Kern Er, Jiří Žemlička   +10 more
openalex   +1 more source

Highly enantioselective synthesis controlled by spin-exchange interaction. [PDF]

Sci Adv
Yan Y, Shaikh M, Beard MC, Gu J, Hendrix I.   +4 more
europepmc   +1 more source

Enantioselective Synthesis of β-Amino Acid via Asymmetric Bromolactamization

, 1999
Sang‐sup Jew, Kyung-hoi Cha, Sang-deog Kang, Yun-hee Woo, Hyung-ook Kim, Hyeung‐geun Park   +5 more
openalex   +1 more source

Highly Enantioselective Organocatalysis with Bidentate Halogen Bond Donors

Angewandte Chemie International Edition, EarlyView.
In a model Mukaiyama aldol reaction with unbiased substrates, high enantioselectivity was achieved with a modifiable bidentate iodine(I)‐based halogen bonding organocatalyst. The crucial role of halogen bonding was confirmed by the low performance of the corresponding hydrogen bond donor and via DFT calculations.
Julian Wolf, Meghana Poliyodath Mohanan, Raphaël Robidas, Revannath L. Sutar, Elric Engelage, Claude Y. Legault, Stefan M. Huber   +6 more
wiley   +1 more source

Synthesis of (R)-(-)-3-Methoxymethyl-3-propyl-3,4-dihydrocoumarin from a Chiral Michael Adduct: Absolute Configurations of the Allylated Products of Enantioselective Radical-Mediated Reactions.

, 1999
Masatoshi Murakata, Yusuke Mizuno, Hiromi Yamaguchi, Osamu Hoshino   +3 more
openalex   +2 more sources

Enantioselective synthesis of (+)-polyzonimine, defensive monoterpene alkaloid produced by a milliped Polyzonium rosalbum, and determination of its S absolute configuration by Its conversion to (4S,5R,6S)-(+)-nitropolyzonamine [PDF]

, 2000
Yasuyo Takagi, Kenji Mori
openalex   +1 more source

Redirecting the Peptide Cleavage Causes Protease Inactivation

Angewandte Chemie International Edition, EarlyView.
Cysteine proteases catalyze substrate cleavage by a two‐step acyl transfer mechanism. Newly designed peptidic inhibitors of human cathepsin B with N‐terminal carbamate warheads undergo a redirected cleavage and generate non‐canonical covalent complexes.
Christian Breuer, Jim Küppers, Anna‐Christina Schulz‐Fincke, Anna Heilos, Carina Lemke, Petra Spiwoková, Janina Schmitz, Laura Cremer, Marta Frigolé‐Vivas, Michael Lülsdorff, Matthias D. Mertens, Filip Wichterle, Miloš Apeltauer, Martin Horn, Erik Gilberg, Norbert Furtmann, Jürgen Bajorath, Ulrike Bartz, Bernd Engels, Michael Mareš, Michael Gütschow   +20 more
wiley   +1 more source

Organocatalyzed diastereo- and enantioselective synthesis of N-N atropisomeric isoindolinones bearing central chirality. [PDF]

Nat Commun
Li X, Wang XZ, Shen B, Chen QY, Xiang H, Yu P, Liu PN.   +6 more
europepmc   +1 more source