Enantioselective nickel-catalyzed dicarbofunctionalization of 3,3,3-trifluoropropene
Nature Communications, 2022 Strategies for the catalytic asymmetric synthesis of trifluoromethylated compounds remain scarce. Here, the authors report the nickel-catalyzed enantioselective dicarbofunctionalization of 3,3,3-trifluoropropene.
Yun-Ze Li +5 more
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Enanatioselective Switch and Potential Applications in Biocatalysis
CHIMIA, 2023 Enantioselectivity has always been a key feature of enzymatic synthesis. In some cases, when enzymes are not strictly enantioselective, by tuning the reaction conditions it is possible to induce an enantioselective switch.
Lucia Robustini, Francesca Paradisi
doaj +1 more source
Strong coupling to circularly polarized photons: towards field-induced enantioselectivity [PDF]
arXiv, 2023 The development of new methodologies for the selective synthesis of individual enantiomers is still one of the major challenges in synthetic chemistry. Many biomolecules, and therefore many pharmaceutical compounds, are indeed chiral. While the use of chiral reactants or catalysts has led to significant progress in the field of asymmetric synthesis, a ...
arxiv
Molecules, 2006 The enantioselective synthesis of the title compound, using Meyers' bicyclic lactam methodology, is described. This compound and a few of its derivatives are useful intermediates in natural product synthesis.
Pierre J. De Clercq +2 more
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Influence of Phosphoramidites in Copper-Catalyzed Conjugate Borylation Reaction [PDF]
, 2012 Copper(I) has become the preferred metal to catalyze the β-boration of α,β-unsaturated carbonyl compounds, and now we demonstrate that easily accessible monodentate chiral ligands, such as phosphoramidites and phosphites, can be convenient alternative ...
Bonet, Amadeu, +6 more
core +4 more sources
Enantioselective [4+2] Annulation to the Concise Synthesis of Chiral Dihydrocarbazoles
iScience, 2020 Summary: A highly efficient phosphine-catalyzed enantioselective [4 + 2] annulation of allenoates with 3-nitroindoles or 3-nitrobenzothiophenes has been developed.
Haiyang Wang +3 more
doaj
Nature Communications, 2021 Chiral acetylenic derivatives are found in many bioactive compounds and are versatile building blocks in organic synthesis. Here, the authors report a mild enantioselective nickel/Lewis acid-catalyzed asymmetric propargylic substitution reaction which is
Xihao Chang +3 more
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Biologically active Phytophthora mating hormone prepared by catalytic asymmetric total synthesis [PDF]
, 2008 A Phytophthora mating hormone with an array of 1,5-stereogenic centers has been synthesized by using our recently developed methodology of catalytic enantioselective conjugate addition of Grignard reagents. We applied this methodology in a diastereo- and
A. J. Minnaard +23 more
core +4 more sources
All-optical coherent control of chiral electronic transitions for highly enantioselective photochemistry [PDF]
arXiv, 2023 Enantioselective photochemistry provides access to unique molecular structures and functions, with deep implications for fundamental science and industrial applications. Current methods for highly enantioselective photochemistry critically rely on chiral sensitisers, as circularly polarised light on its own yields vanishingly weak enantioselectivity ...
arxiv
Spontaneous Mirror Symmetry Breaking in the Limited Enantioselective Autocatalysis Model: Abyssal Hydrothermal Vents as Scenario for the Emergence of Chirality in Prebiotic Chemistry [PDF]
Astrobiology, Volume 13, Number 2, 2013, 2013 The emergence of chirality in enantioselective autocatalysis for compounds unable to transform according to the Frank-like reaction network is discussed with respect to the controversial limited enantioselectivity (LES) model composed of coupled enantioselective and non-enantioselective autocatalyses.
arxiv +1 more source