Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Five-, Six-, and Seven-Membered β-Substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters [PDF]
, 2011 The first enantioselective Pd-catalyzed construction of all-carbon quaternary stereocenters via 1,4-addition of arylboronic acids to β-substituted cyclic enones is reported. Reaction of a wide range of arylboronic acids and cyclic enones using a catalyst
Gatti, Michele +3 more
core +2 more sources
Enantioselective Total Synthesis of FR900482 [PDF]
The Journal of Organic Chemistry, 2004 The development of two approaches for the enantioselective total synthesis of FR900482 is described. A precursor for the formation of the benzazocine ring was assembled effectively by a modification of the Sonogashira coupling of an aryl triflate with a chiral acetylene unit derived from tartaric acid and the subsequent novel ketone formation via ...
Masashi, Suzuki +3 more
openaire +2 more sources
Nature Communications, 2018 Catalytic enantioselective synthesis of trifluoromethylthiolated molecules remains a challenge. Here, the authors report a bifunctional selenide-catalyzed approach for the synthesis of structurally complex chiral trifluoromethylthiolated ...
Jie Luo +3 more
doaj +1 more source
Enantioselective Synthesis of α‐Aminopropargylphosphonates. [PDF]
ChemInform, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rajasekhar, Dodda, Cong-Gui, Zhao
openaire +2 more sources
Beilstein Journal of Organic ChemistryThe desymmetric enantioselective reduction of cyclic 1,3-dicarbonyl compounds is a powerful tool for the construction of ring systems bearing multiple stereocenters including all-carbon quaternary stereocenters, which are widely useful chiral building ...
Dong-Xing Tan, Fu-She Han
doaj +1 more source
[2,2′-Bipyridin]-6(1H)-one, a Truly Cooperating Ligand in the Palladium-Mediated C–H Activation Step: Experimental Evidence in the Direct C-3 Arylation of Pyridine [PDF]
, 2018 Producción CientíficaThe ligand [2,2′-bipyridin]-6(1H)-one (bipy-6-OH) has a strong accelerating effect on the Pd- catalyzed direct arylation of pyridine or arenes.
Albéniz Jiménez, Ana Carmen +2 more
core +4 more sources
Enantioselective nickel-catalyzed dicarbofunctionalization of 3,3,3-trifluoropropene
Nature Communications, 2022 Strategies for the catalytic asymmetric synthesis of trifluoromethylated compounds remain scarce. Here, the authors report the nickel-catalyzed enantioselective dicarbofunctionalization of 3,3,3-trifluoropropene.
Yun-Ze Li +5 more
doaj +1 more source
Modern Synthetic Strategies with Organoselenium Reagents: A Focus on Vinyl Selenones
Molecules, 2021 In recent years, vinyl selenones were rediscovered as useful building blocks for new synthetic transformations. This review will highlight these advances in the field of multiple-bond-forming reactions, one-pot synthesis of carbo- and heterocycles ...
Martina Palomba +3 more
doaj +1 more source
Enantioselective Synthesis of 5-epi-Citreoviral Using Ruthenium-Catalyzed Asymmetric Ring-Closing Metathesis [PDF]
, 2009 Chiral ruthenium olefin metathesis catalysts can perform asymmetric ring-closing reactions in ≥90% ee with low catalyst loadings. To illustrate the practicality of these reactions and the products they form, an enantioselective total synthesis of 5-epi ...
Funk, Timothy W.
core +2 more sources
Enantioselective Total Synthesis of (−)‐Deoxoapodine [PDF]
Angewandte Chemie International Edition, 2017 AbstractThe first enantioselective total synthesis of (−)‐deoxoapodine is described. Our synthesis of this hexacyclic aspidosperma alkaloid includes an efficient molybdenum‐catalyzed enantioselective ring‐closing metathesis reaction for the desymmetrization of an advanced intermediate that introduces the C5‐quaternary stereocenter.
Taek Kang +4 more
openaire +3 more sources