Results 41 to 50 of about 83,738 (273)
Nature Communications, 2021 Chiral acetylenic derivatives are found in many bioactive compounds and are versatile building blocks in organic synthesis. Here, the authors report a mild enantioselective nickel/Lewis acid-catalyzed asymmetric propargylic substitution reaction which is
Xihao Chang +3 more
doaj +1 more source
Asymmetric Hydrogenation of 1-alkyl and 1-aryl vinyl benzoates: a broad scope procedure for the highly enantioselective synthesis of 1-substituted ethyl benzoates [PDF]
, 2014 The enantioselective hydrogenation of enol esters of formula CH2=C(OBz)R with rhodium catalysts based on phosphine-phosphite ligands (P-OP) has been studied.
Cadierno, Victorio +4 more
core +1 more source
Photoresponsive Gas‐Permeable Membranes: Fundamentals, Innovations, and Prospects
Advanced Functional Materials, EarlyView.Photoresponsive gas‐permeable membranes can be potentially used for smart packing, carbon capture, hydrogen purification, and optical gas valves due to their remote and non‐contact activation, precise spatial and temporal control, and reversible switching capabilities.
Zhuan Wang +6 more
wiley +1 more source
Enantioselective desymmetrization strategy of prochiral 1,3-diols in natural product synthesis
Beilstein Journal of Organic ChemistryEnantioselective desymmetrization is employed as a powerful tool for the creation of chiral centers. Within this scope, the enantioselective desymmetrization of prochiral 1,3-diols, which generates chiral centers by enantioselective functionalization of ...
Lihua Wei +3 more
doaj +1 more source
Focus on chirality of HIV-1 non-nucleoside reverse transcriptase inhibitors [PDF]
, 2016 Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core +2 more sources
Tailoring the Properties of Functional Materials With N‐Oxides
Advanced Functional Materials, EarlyView.The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich +5 more
wiley +1 more source
Catalytic synthesis of chiral sulfinimidate esters via oxidative esterification of sulfenamides
Nature CommunicationsAza-sulfur compounds, such as sulfilimines, sulfoximines, etc, are increasingly recognized as essential contributors to advancements in drug development and asymmetric synthesis.
Hua-Jie Jiang +8 more
doaj +1 more source
Nature Communications, 2017 Enantioselective synthesis of six-membered oxacycles with multiple stereogenic centres is essential for the discovery of new therapeutic agents. Here the authors show organocatalytic cycloetherification for the highly enantio- and diastereoselective ...
Naoki Yoneda +4 more
doaj +1 more source
A selective transformation of enals into chiral γ-amino alcohols. [PDF]
, 2013 A one-pot synthesis of chiral amino alcohols from α,β-unsaturated aldehydes is reported which circumvents competitive 1,2- versus 1,4-boryl addition, by means of using a sterically hindered amine-derived imine.
Batsanov, A. S. +5 more
core +1 more source
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
Advanced Functional Materials, EarlyView.This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source