Results 101 to 110 of about 149,811 (326)

A unique method for highly enantioselective synthesis of N–C axially chiral compounds [PDF]

, 2021
Osamu Kitagawa
openalex   +1 more source

Emergent Strategies for Catalytic Enantioselective Direct Thiocyanation and Selenocyanation Reactions

SynOpen, 2023
Floris Buttard, Tatiana Besset
doaj   +1 more source

Enantioselectivity in Vanadium-Dependent Haloperoxidases of Different Marine Sources for Sulfide Oxidation to Sulfoxides

Marine Drugs
This study explores the reasons behind the variations in the enantioselectivity of the sulfoxidation of methyl phenyl sulfide by marine-derived vanadium-dependent haloperoxidases (VHPOs). Twelve new VHPOs of marine organisms were overexpressed, purified,
Yun-Han Zhang, Ya-Ting Zou, Yong-Yi Zeng, Lan Liu, Bi-Shuang Chen   +4 more
doaj   +1 more source

Semi-rational engineering of a thermostable aldo–keto reductase from Thermotoga maritima for synthesis of enantiopure ethyl-2-hydroxy-4-phenylbutyrate (EHPB)

Scientific Reports, 2017
A novel aldo-keto reductase Tm1743 characterized from Thermotoga maritima was explored as an effective biocatalyst in chiral alcohol production. Natural Tm1743 catalyzes asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate (EOPB) at high efficiency, but ...
Zhiguo Wang, Shuo Zhou, Shuangling Zhang, Sa Zhang, Fangmeng Zhu, Xiaolu Jin, Zhenming Chen, Xiaoling Xu   +7 more
doaj   +1 more source

Intermolecular Enantioselective Nickel‐Catalyzed Arylation of Un‐Activated C(sp3)─H Bond

Angewandte Chemie International Edition, EarlyView.
Ni: a new solution for asymmetric C(sp3)─H activation. The stereoselective synthesis of all‐carbon quaternary stereogenic centres is achieved via enantioselective C(sp3)─H arylation using a Ni‐BINOL‐derived catalyst. Rational catalytic cycle design uncovers a new reaction pathway that can efficiently induce chiral information during the stereoselective
Erwan Brunard, Fengjie Huang, Àlex Díaz‐Jiménez, Sofiya Kostiukovska, Joanna Wencel‐Delord   +4 more
wiley   +1 more source

C₂-Symmetric Dinickel Catalysts for Enantioselective [4 + 1]-Cycloadditions

, 2020
Michael J. Behlen, Christopher Uyeda
openalex   +2 more sources

Photochemical Deracemization of Chromanes and its Application to the Synthesis of Enantiopure Bioactive Compounds. [PDF]

Angew Chem Int Ed Engl
Various substituted chromane‐2‐carboxamides were successfully deracemized by employing a chiral benzophenone (BP, 10 mol%) as photocatalyst and an achiral thiol as additive (20 mol%). The method was applied to the concise enantioselective synthesis of five active pharmaceutical ingredients.
Ghosh B, Iglhaut M, Babushkina D, Pauls M, Bannwarth C, Bach T.   +5 more
europepmc   +3 more sources

Enantioselective Hydroalkylation of α,β-Unsaturated Amides through Reversed syn-Hydrometallation of NiH

, 2021
Fang Zhou, Shaolin Zhu
openalex   +1 more source

Essential oil composition and enantioselective profile of Juniperus communis var. depressa (Cupressaceae) from Utah [PDF]

, 2023
Ariel Poulson, Tyler M. Wilson, Reilly E. Sonstrom, Audra Davis, Justin L. Neill, Richard E. Carlson   +5 more
openalex   +1 more source

Synthesis of α‐Pentafluorosulfanylated‐β2,3‐Amino Esters

ChemistryEurope, EarlyView.
De novo α‐SF5‐β2,3‐amino esters are now accessible through a straightforward aza‐Michael reaction using a series of newly developed (E)‐α‐SF5‐α,β‐unsaturated esters. Two new, highly functionalized, contiguous tertiary stereocenters are formed with diastereodivergence governed by the choice of solvent and/or base.
Thi Mo Nguyen, Guilhem Colomer, Oscar Maugue‐Sauze, Nicolas Blanchard, Vincent Bizet, Dominique Cahard   +5 more
wiley   +1 more source