Results 131 to 140 of about 19,236 (236)

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis

Experimental Physiology, Volume 111, Issue 6, Page 2918-2944, 1 June 2026.
Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza, Marie Kempe, Sofia Grimmelsmann, Luiz Felipe Tavares, Ester Moreira De Castro‐Carletti, Angela Viegas Andrade, Liz Dennett, Harry Von Piekartz, Jorge Fuentes Contreras, Susan Armijo‐Olivo   +9 more
wiley   +1 more source

Endocannabinoids in stressed humans

European Journal of Psychotraumatology, 2012
Rationale : The endocannabinoid system has been shown to be an important regulator of the stress response and adaptation to stressful situations and environments in animals.
Gustav Schelling
doaj   +1 more source

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

The Journal of Physiology, Volume 604, Issue 11, Page 4186-4207, 1 June 2026.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra, Laurent Chatre, Benoit Bernay, Julien Pontin, Mirjam F. Mastik, Azuwerus van Buiten, Dalibor Nakládal, Bastiaan S. Star, Jan‐Luuk Hillebrands, Guido Krenning   +9 more
wiley   +1 more source

Hardwiring the bain: Endocannabinoids shape neuronal connectivity

, 2007
The roles of endocannabinoid signaling during central nervous system development are unknown. We report that CB(1) cannabinoid receptors (CB(1)Rs) are enriched in the axonal growth cones of gamma-aminobutyric acid-containing (GABAergic) interneurons in ...
Berghuis, P (15540404), Rajnicek, AM (15540407), Marsicano, G (15540425), Alison Canty (14733109), Yanagawa, Y (15540437), Harkany, T (15540449), Morozov, YM (15540410), Rakic, P (15540440), Lutz, B (15540443), Ross, RA (15540413), Monory, K (15540422), Mulder, J (15540416), Katona, I (15540434), Urban, GM (15540419), Matteoli, M (15540428), Mackie, K (15540446), Irving, AJ (15540431)   +16 more
core  

Heterogeneous metabolic response of endothelial cells from different vascular beds to experimental hyperglycaemia and metformin

The Journal of Physiology, Volume 604, Issue 11, Page 4208-4224, 1 June 2026.
Abstract figure legend Diabetes mellitus is associated with vascular pathology that leads to vascular complications in several tissues, such as retinopathy of the eye. Endothelial dysfunction plays a pivotal role in the progression of each complication.
C. McAleese, G. Joudah, I. P. Salt, J. R. Petrie, J. M. Leiper, Laura B. Dowsett   +5 more
wiley   +1 more source

Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner

, 2010
Endocannabinoids are amides and esters of long chain fatty acids that can modulate ion channels through both receptor-dependent and receptor-independent effects.
Tamargo Menéndez, Juan, Osuna, Lourdes, Lillo, María Pilar, Delpón Mosquera, María Eva, Caballero Collado, Ricardo, Gómez García, Ricardo, Amorós García, Irene, Barana Muñoz, Adriana   +7 more
core   +1 more source

The endogenous cannabinoid system gates plasticity of tonic GABA inhibition

The Journal of Physiology, Volume 604, Issue 12, Page 4984-5010, 15 June 2026.
Abstract figure legend Postsynaptic depolarisation and increases in intracellular Ca2+ ([Ca2+]i) trigger the synthesis of endocannabinoids (eCBs), which are hypothesised to enhance tonic GABAergic inhibition via two primary pathways. In the proposed autocrine mechanism, eCBs activate postsynaptic somatodendritic or mitochondrial CB1 receptors ...
Roberto Colangeli, Fiorenzo Conti
wiley   +1 more source

CMR‐derived left ventricular pressure‐volume loops enhance individualized assessment of disease severity and prognosis in pulmonary arterial hypertension in adults

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract In pulmonary arterial hypertension (PAH), increased pulmonary vascular resistance (PVR) causes right ventricular pressure overload and left ventricular (LV) underfilling. We investigated LV mechanics and their prognostic value in PAH using cardiovascular magnetic resonance (CMR)‐derived LV pressure‐volume (PV) loops.
Alessandro Castiglione, Elsa Bergström, Barbro Kjellström, Göran Rådegran, Håkan Arheden, Ellen Ostenfeld   +5 more
wiley   +1 more source

High Relevance of Fatty Acid Oxidation in a Migrating Mammal, the Nathusius' Pipistrelle (Pipistrellus nathusii)

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Bats can sustain powered flight, but their reliance on fatty acid oxidation may limit long‐distance migration compared to birds. Using untargeted metabolomics, we analyzed blood metabolites of Nathusius' pipistrelle under controlled flight and migratory field conditions to identify fuel use.
Alesia Walker, Thuy Thanh Truong, Martin Klingenspor, Anders Hedenström, Gunars Pētersons, Philippe Schmitt‐Kopplin, Shannon E. Currie, Christian C. Voigt   +7 more
wiley   +1 more source

Neurotransmission: Emerging Roles of Endocannabinoids

, 2005
Postsynaptic release of endocannabinoids can inhibit presynaptic neurotransmitter release on short and long timescales. This retrograde inhibition occurs at both excitatory and inhibitory synapses and may provide a mechanism for synaptic gain control ...
Anatol C. Kreitzer, Kreitzer, Anatol C.
core   +1 more source