Results 121 to 130 of about 19,236 (236)
Abstract Background Heat stress (HS) poses a significant challenge to dairy production under climate change, as it compromises fertility, productivity and overall health in cows. This seasonal observational cross‐sectional study investigated how environmental temperature affects oxidative status, inflammatory responses and endocannabinoid system (ECS ...
Alice Carbonari +10 more
wiley +1 more source
Endocannabinoids and reproductive endocrinology
The endocannabinoids anandamide and 2-arachidonoylglycerol mimic Delta(9)-tetrahydrocannabinol, the chemical component responsible for the psychoactive properties of Cannabis sativa, by binding to both type 1 and type 2 cannabinoid receptors ...
Maccarrone M
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The role of endocannabinoids in pregnancy
Endocannabinoids are a family of lipid signalling molecules. As with prostaglandins (PGs), endocannabinoids are derived from polyunsaturated fatty acids and affect cell function via receptor-mediated mechanisms.
McKirdy, Natalie C. +4 more
core +1 more source
Abstract Background and aims Epidemiologic research suggests that adolescent cannabis use is associated with psychological distress (i.e. depression and anxiety symptoms); however, most studies have relied on 20th‐century data, when cannabis was significantly less potent than today.
André J. McDonald +12 more
wiley +1 more source
Main correlations of circulating endocannabinoids.
Values are age- and sex-adjusted partial correlations with Bonferroni adjustment for multiple testing for a significance level < 0.05.AEA, anandamide; PEA, palmitoylethanolamide; NS, non-significant.Main correlations of circulating endocannabinoids.
Marcia Mattos Gonçalves Pimentel (825105) +8 more
core +1 more source
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová +12 more
wiley +1 more source
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen +11 more
wiley +1 more source
Reduced taste sensitivity to 6-n-propylthiouracil (PROP), a genetic trait regarded as a general index for oral chemosensory perception, has been associated with a calorie-rich food preference and lower circulating endocannabinoid levels in participants ...
Gianfranca Carta +9 more
doaj +1 more source
Guessing at Ghosts in the Machine
ABSTRACT As AI grows ever more complex and ubiquitous, its moral status becomes increasingly pressing. But knowing whether an AI has moral status is only part of the ethical puzzle. To determine how we ought to treat such entities, we must know not only whether AIs have moral status, but also about the content of their interests—what contributes to ...
Helen Yetter‐Chappell
wiley +1 more source
The Effect of Endocannabinoids on Nociceptive Learning
Chronic pain is a national health crisis. Opioids are one of the primary treatment options for severe pain, but due to their addictive nature, there is an increasing need for alternative treatments.
Dohn, John, Hoynoski, Jessica
core

