Results 111 to 120 of about 32,682 (238)

Participants with Normal Weight or with Obesity Show Different Relationships of 6-n-Propylthiouracil (PROP) Taster Status with BMI and Plasma Endocannabinoids

open access: yesScientific Reports, 2017
Reduced taste sensitivity to 6-n-propylthiouracil (PROP), a genetic trait regarded as a general index for oral chemosensory perception, has been associated with a calorie-rich food preference and lower circulating endocannabinoid levels in participants ...
Gianfranca Carta   +9 more
doaj   +1 more source

Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy

open access: yesMolecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley   +1 more source

Disrupted endocannabinoid signaling contributes to systemic inflammation in acute pancreatitis

open access: yesThe Journal of Pathology, Volume 269, Issue 4-5, Page 462-477, August 2026.
Abstract Acute pancreatitis (AP) is an inflammatory disease that can lead to systemic complications in severe cases. The endocannabinoid system has emerged as a potential modulator of inflammation in AP. We investigated the role of the endocannabinoid 2‐arachidonoylglycerol (2‐AG) and the cannabinoid receptors CB1 and CB2 during AP.
Paula Goncalves‐Romeu   +7 more
wiley   +1 more source

Endocannabinoids in stressed humans

open access: yesEuropean Journal of Psychotraumatology, 2012
Rationale : The endocannabinoid system has been shown to be an important regulator of the stress response and adaptation to stressful situations and environments in animals.
Gustav Schelling
doaj   +1 more source

Could NAPQI Contribute to Paracetamol Analgesia? Redox Modulation of Kv7 Ion Channels

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Paracetamol (acetaminophen, APAP) is one of the most widely used analgesic and antipyretic drugs worldwide, yet its mechanism of action remains incompletely understood. While several pathways have been proposed, including cyclooxygenase inhibition and endocannabinoid modulation via AM404, none fully account for its pharmacological profile. The
Sara M‐Alicante   +6 more
wiley   +1 more source

The Relationship Between (Endo)cannabinoids, the Microbiome and Melanoma

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
CB1 and CB2 receptors are widely distributed in both normal and cancerous cells. Cannabinoids have a positive impact on reducing tumor growth in mice. A positive relationship exists between CB2 receptors and survival in skin melanoma. However, there is a negative impact on non‐small cell lung cancer and colon cancer, whereas a higher association of CB1
Farideh A. Javid   +3 more
wiley   +1 more source

Working Through Your Emotions: Exercise Repairs the Experience of Positive and Negative Emotions Through Cognitive Emotion Regulation After a Recalled Stressor

open access: yesStress and Health, Volume 42, Issue 4, August 2026.
ABSTRACT Exercise is suggested to help regulate emotions; however, its role in the underlying cognitive emotion regulation process—starting with a cue, cognitive actions to modify emotions, and desirable emotional changes—has not yet been demonstrated.
Juriena D. de Vries, Keri A. Pekaar
wiley   +1 more source

Adolescent Dietary Supplementation of Omega‐3 Polyunsaturated Fatty Acids Alleviates PTSD‐Like Fear Memory and Affective Dysregulation in Rats

open access: yesSmart Medicine, Volume 5, Issue 4, August 2026.
Adolescent omega‐3 polyunsaturated fatty acid supplementation enhances resilience to trauma in adulthood. DHA/EPA intake restores gut microbial balance, reprograms lipid metabolism, and normalizes prefrontal PI3K/AKT/mTOR signaling. These changes may collectively mitigate PTSD‐like fear memory and affective dysregulation. ABSTRACT Post‐traumatic stress
Wenjing Li   +7 more
wiley   +1 more source

Might modulation of the endocannabinoid system provide a potential dual therapeutic strategy for osteoporosis and depression?

open access: yes
General Psychiatry, Volume 39, Issue 4, August 2026.
Peng Wei   +6 more
wiley   +1 more source

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