Results 101 to 110 of about 45,559 (245)

Spatiotemporal remodelling of the cloacal region determines the position of the anal opening in mouse embryos

open access: yesJournal of Anatomy, EarlyView.
In E13.25 mouse embryo, the urorectal septum consistently positioned on the dorsodistal side of the cloacal membrane. Through 3D reconstruction of the cloacal internal space, we revealed that the position of the anal opening is established prior to cloacal membrane rupture and is located at the junction between the hindgut lumen (blue) and an expanded ...
Weiyi Wang, Masayo Harada, Keiichi Akita
wiley   +1 more source

Primitive to visceral endoderm maturation is essential for mouse epiblast survival beyond implantation

open access: yesiScience
Summary: The implantation of the mouse blastocyst initiates a complex sequence of tissue remodeling and cell differentiation events required for morphogenesis, during which the extraembryonic primitive endoderm transitions into the visceral endoderm ...
Antonia Weberling   +5 more
doaj   +1 more source

Notochord Patterning of the Endoderm

open access: yesDevelopmental Biology, 2001
Endodermally derived organs of the gastrointestinal and respiratory system form at distinct anterioposterior and dorsoventral locations along the vertebrate body axis. This stereotyped program of organ formation depends on the correct patterning of the endodermal epithelium so that organ differentiation and morphogenesis occur at appropriate positions ...
Cleaver, Ondine, Krieg, Paul A
openaire   +2 more sources

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

open access: yesExperimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Three-Dimensional Trilineage Differentiation Conditions for Human Induced Pluripotent Stem Cells

open access: yesBioengineering
Human induced pluripotent stem cells (hiPSCs) hold great potential for regenerative medicine. However, optimizing their differentiation into specific lineages within three-dimensional (3D) scaffold-based culture systems that mimic in vivo environments ...
Md Sharifur Rahman   +7 more
doaj   +1 more source

endoderm

open access: yes
Citation: 'endoderm' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10659 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. ABSTRACT Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen   +9 more
wiley   +1 more source

Ethanol Induces Craniofacial Defects in Bmp Mutants Independent of nkx2.3 by Elevating Cranial Neural Crest Cell Apoptosis

open access: yesBiomedicines
Background: Craniofacial malformations lie at the heart of fetal alcohol spectrum disorders (FASDs). While there is growing evidence for a genetic component in FASDs, little is known of the cellular mechanisms underlying these ethanol-sensitive loci in ...
Hieu D. L. Vo, C. Ben Lovely
doaj   +1 more source

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