Therapeutic Potential of an Endolysin Derived from Kayvirus S25-3 for Staphylococcal Impetigo
Viruses, 2019 Impetigo is a contagious skin infection predominantly caused by Staphylococcus aureus. Decontamination of S. aureus from the skin is becoming more difficult because of the emergence of antibiotic-resistant strains.
Ichiro Imanishi +7 more
doaj +1 more source
Two Distinct Modes of Lysis Regulation in Campylobacter Fletchervirus and Firehammervirus Phages
Viruses, 2020 Campylobacter phages are divided into two genera; Fletchervirus and Firehammervirus, showing only limited intergenus homology. Here, we aim to identify the lytic genes of both genera using two representative phages (F352 and F379) from our collection. We
Athina Zampara +4 more
doaj +1 more source
Frontiers in Medicine, 2023 Chronic prostatitis (CP) is a common inflammatory condition of the prostate that is estimated to effect 2%–10% of the world’s male population. It can manifest as perineal, suprapubic, or lower back pain and urinary symptoms occurring with either ...
Roy H. Stevens +7 more
doaj +1 more source
Monitoring in real time the formation and removal of biofilms from clinical related pathogens using an impedance-based technology [PDF]
, 2017 Bacteria found in diverse ecosystems grow in a community of aggregated cells that favors their survival and colonization. Different extracellular polymeric substances are used to entrap this multispecies community forming a biofilm, which can be ...
García Suárez, María Pilar +4 more
core +1 more source
PEGylating a bacteriophage endolysin inhibits its bactericidal activity [PDF]
AMB Express, 2011 Bacteriophage endolysins (lysins) bind to a cell wall substrate and cleave peptidoglycan, resulting in hypotonic lysis of the phage-infected bacteria. When purified lysins are added externally to Gram-positive bacteria they mediate rapid death by the same mechanism.
Resch, G. +2 more
openaire +3 more sources
Characterization of Streptococcus gordonii prophage PH15: complete genome sequence and functional analysis of phage-encoded integrase and endolysin [PDF]
, 2008 Streptococcus gordonii OMZ1039, isolated from supragingival dental plaque, was found to harbour a prophage, PH15, whose excision could be induced by mitomycin treatment. Phage PH15 belongs to the Siphoviridae.
van der Ploeg, J R
core +1 more source
Microbial Cell FactoriesBackground Staphylococcus aureus and its single or mixed biofilm infections seriously threaten global public health. Phage therapy, which uses active phage particles or phage-derived endolysins, has emerged as a promising alternative strategy to ...
He Liu +13 more
semanticscholar +1 more source
Inhibition of Listeria monocytogenes by Phage Lytic Enzymes Displayed on Tailored Bionanoparticles
Foods, 2022 The high mortality rate associated with Listeria monocytogenes and its ability to adapt to the harsh conditions employed in food processing has ensured that this pathogen remains a serious problem in the ready-to-eat food sector.
Edel Stone +6 more
doaj +1 more source
npj Biofilms and Microbiomes, 2023 Antibiotic resistance and the ability to form biofilms of Enterococcus faecalis have compromised the choice of therapeutic options, which triggered the search for new therapeutic strategies, such as the use of phage endolysins and antimicrobial peptides.
Huihui Zhang +8 more
semanticscholar +1 more source
Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]
, 2017 Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves +4 more
core +1 more source