Results 51 to 60 of about 89 (88)

Bacteriophages and Endolysins Used in the Biocontrol of Staphylococcus aureus

Microorganisms
Staphylococcus aureus is a major foodborne pathogen associated with contamination of dairy and meat products, posing a persistent challenge to food safety due to its biofilm formation and resistance to multiple antibiotics. In this review, we summarize recent advances in the use of bacteriophages and phage-derived endolysins as targeted biocontrol ...
Maryoris E. Soto Lopez, Ana Margarita Otero-Herrera, Fernando Mendoza-Corvis, Jose Jorge Salgado-Behaine, Rocio López-Vergara, Ana M. Hernández-Arteaga, Derrick Cortessi, Pedro M. P. Vidigal, Omar Pérez-Sierra   +8 more
openaire   +2 more sources

Efficacy of Inhalable Endolysin Cpl-1 Formulations in Combination with Gentamicin or Endolysin Pal in a Murine Lung Infection Model

Pharmaceutical Research
Abstract Purpose Inhalable liquid formulation of endolysins represents a promising alternative to conventional antibiotics. Dry powder formulations offer improved stability for endolysin pulmonary delivery.
Wang, Yuncheng, Stevens, Maxwell T., Wang, Trixie, Alreja, Adit B., Nelson, Daniel C., Britton, Warwick J., Chan, Hak-Kim   +6 more
openaire   +2 more sources

Molecular Dissection of Phage Endolysin [PDF]

Journal of Biological Chemistry, 2014
Amol Arunrao Pohane, Himanshu Joshi, Vikas Jain   +2 more
openaire   +1 more source

Structure prediction of endolysin SU57e

Endolysins are used by bacteriophages to break down the cell wall of the bacterial host towards the end of the infection cycle. Endolysins are interesting options for the creation of antibacterial substances and domains from endolysins can be combined with domains from other proteins to create antibacterial constructs.
Seijsing, Fredrik, Seijsing, Johan, Nilsson, Anders   +2 more
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Crystal structure of the engineered endolysin mtEC340M

Acta Crystallographica Section F Structural Biology Communications, 2023
Endolysins produced by bacteriophages play essential roles in the release of phage progeny by degrading the peptidoglycan layers of the bacterial cell wall. Bacteriophage-encoded endolysins have emerged as a new class of antibacterial agents to combat surging antibiotic resistance.
Jee-Min Wang, Seung-Hyeon Seok, Won-Su Yoon, Ji-Hun Kim, Min-Duk Seo   +4 more
openaire   +2 more sources

A Computational Method for the Identification of Endolysins and Autolysins

Protein & Peptide Letters, 2020
Background: Cell lytic enzyme is a kind of highly evolved protein, which can destroy the cell structure and kill the bacteria. Compared with antibiotics, cell lytic enzyme will not cause serious problem of drug resistance of pathogenic bacteria. Thus, the study of cell wall lytic enzymes aims at finding an efficient way for curing bacteria infectious.
Lei Xu, Guangmin Liang, Baowen Chen, Xu Tan, Huaikun Xiang, Changrui Liao   +5 more
openaire   +2 more sources

The structure of DLP12 endolysin exhibiting alternate loop conformation and comparative analysis with other endolysins

Proteins: Structure, Function, and Bioinformatics, 2017
AbstractThe lytic enzyme, endolysin, is encoded by bacteriophages (phages) to destroy the peptidoglycan layer of host bacterial cells. The release of phage progenies to start the new infection cycle is dependent on the cell lysis event. Endolysin encoded by DLP12 cryptic prophage is a SAR endolysin which is retained by the bacterium presumably due to ...
Kesavan Babu, Arockiasamy Arulandu, Krishnaswamy Sankaran   +2 more
openaire   +2 more sources

Bacteriophage endolysins: applications for food safety

Current Opinion in Biotechnology, 2016
Bacteriophage endolysins (peptidoglycan hydrolases) have emerged as a new class of antimicrobial agents useful for controlling bacterial infection or other unwanted contaminations in various fields, particularly in the light of the worldwide increasing frequency of drug-resistant pathogens.
Mathias, Schmelcher, Martin J, Loessner
openaire   +2 more sources

Bacteriophage endolysins

In the last phase of their life cycle, bacteriophages form lytic enzymes known as bacteriophage endolysins that destroy the bacterial cell wall and liberate new virions. Endolysins have emerged as high-scope antimicrobial agents, especially against Gram-positive infections, due to their specificity, rapid action, and ability to target essential cell ...
Nidhi, Prajapati, Dharmendra, Prajapati, Anil, Patani, Sherzodbek, Tashbaev, Gulomov Gafurjon Shavkatbek, Ugli, Ashish, Patel   +5 more
openaire   +2 more sources

C‐terminal anchor endolysins—proposing a third class of tailed bacteriophage endolysins

FEBS Letters
Endolysins—enzymes produced by tailed bacteriophages to degrade bacterial cell walls—have traditionally been classified as canonical or signal‐anchor‐release (SAR) endolysins. However, analysis of expanding viral (meta)genomic data has revealed a third class, which we designate as C‐terminal anchor (CTA) endolysins.
Elina Cernooka, Nikita Zrelovs, Andris Kazaks   +2 more
openaire   +2 more sources