Results 61 to 70 of about 5,520 (176)

New Finnlakevirus Isolate FLiP‐2 Provides Insight Into the Ecology of ssDNA Phages in Flavobacterium Hosts

Environmental Microbiology, Volume 28, Issue 6, June 2026.
Despite the small genome size, ssDNA virus FLiP is remarkably well adapted to the seasonal variations of boreal fresh waters demonstrating excellent condition and host specific flexibility in its host interactions. FLiP plaques detected far from the original infection site represent a previously undescribed phenomenon, likely caused by the phage non ...
Kati Mäkelä, Elina Laanto, Reetta Penttinen, Janne Ravantti, Kim Kreuze, Lotta‐Riina Sundberg   +5 more
wiley   +1 more source

Psyllid Cysteine Cathepsins Directly Cleave the Outer Membrane Protein BamD of Citrus Huanglongbing Pathogen

Plant Biotechnology Journal, Volume 24, Issue 6, Page 3989-4004, June 2026.
ABSTRACT Candidatus Liberibacter asiaticus (CLas), the causative agent of citrus Huanglongbing (HLB), is transmitted by Asian citrus psyllid, Diaphorina citri; however, the role of the insect's immune effectors in defending against CLas remains poorly understood. This study reveals that D.
Yu Du, Yu Bin, Jinhua Yang, Manman Hu, Liqin Jiang, Qiaoling Su, Shiyi Lin, Lanfeng Qu, You Li, Taiyun Wei   +9 more
wiley   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Bioinformatic Analysis of Prophage Endolysins and Endolysin-Like Genes from the Order Lactobacillales

Nova Biotechnologica et Chimica, 2012
Bioinformatic Analysis of Prophage Endolysins and Endolysin-Like Genes from the Order Lactobacillales Endolysins belonging to the group of peptigoglycan hydrolases, which are able to cleave peptidoglycan in bacterial cell walls, become an extensively studied group of enzymes.
Lenka Maliničová, Peter Pristaš, Peter Javorský   +2 more
openaire   +1 more source

Bacterial Extracellular Vesicles: New Hype or Hope to Explain Reproductive Host–Microbiota Interactions

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Rapid advances in microbiome research are transforming our understanding of human health and disease, with growing focus on the female reproductive tract as a critical but understudied niche. Evidence for a local microbiome largely derives from bacterial nucleic acid detection; however, the biological relevance of these signals remains debated,
Hannah Wein, Paula Iglesias‐Moreno, Apostol Apostolov, Andres Salumets, Damián O. Muzzio, Alberto Sola‐Leyva   +5 more
wiley   +1 more source

Interfacial Chemistry‐Tailored Silica&Metal‐Based Heterostructures: from Rational Design to Antibacterial Applications

Small, Volume 22, Issue 26, 8 May 2026.
This review explores how interfacial engineering of silica&metal‐based nanohybrids enables precise architectural control, leveraging the structural and functional contributions of silica to overcome the inherent limitations of meta‐based materials. The antibacterial performance of these nanohybrids including membrane disruption, stimuli‐responsive ...
Dan Cheng, Yuchao Gu, Chengzhong Yu
wiley   +1 more source

Gut Commensal Klebsiella pneumoniae Extracellular Vesicles Shape a Liver Microenvironment Conducive to Gut‐Liver Bacterial Translocation and Pro‐Tumorigenic Processes

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Bacterial extracellular vesicles (EVs) are emerging mediators of host–microbe communication; however, their role in human disease remains unclear. Here, we identify two bacterial small tRNAs (tsRNAs) enriched in gut commensal Klebsiella pneumoniae‐derived EVs (KpEVs) that are markedly elevated in the serum of patients with hepatocellular ...
Shogo Tsubaki, Sho Nashimoto, Rika Tanaka, Touya Toyomoto, Hiroyasu Tsutsuki, Ken Kato, Jun Nakayama, Kiminori Kimura, Kazuki Oshima, Yusuke Yamamoto, Takuji Okusaka, Minoru Esaki, Nobuhiro Kawai, Nobuyuki Ota, Yusuke Yoshioka, Takahiro Ochiya, Yoshimasa Saito, Tomohiro Sawa, Katsuto Hozumi, Juntaro Matsuzaki, Hitoshi Tsugawa   +20 more
wiley   +1 more source

A Novel Phage PD-6A3, and Its Endolysin Ply6A3, With Extended Lytic Activity Against Acinetobacter baumannii

Frontiers in Microbiology, 2019
With widespread abuse of antibiotics, bacterial resistance has increasingly become a serious threat. Acinetobacter baumannii has emerged as one of the most important hospital-acquired pathogens worldwide.
Minle Wu, Kongying Hu, Youhua Xie, Yili Liu, Di Mu, Huimin Guo, Zhifan Zhang, Yingcong Zhang, Dong Chang, Yi Shi   +9 more
doaj   +1 more source

A bacteriophage endolysin that eliminates intracellular streptococci

eLife, 2016
PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling intracellular Spy that often underlies refractory infections. We show that the PlyC holoenzyme, mediated by its PlyCB subunit, crosses epithelial cell membranes and clears intracellular Spy in a dose ...
Yang Shen, Marilia Barros, Tarek Vennemann, D Travis Gallagher, Yizhou Yin, Sara B Linden, Ryan D Heselpoth, Dennis J Spencer, David M Donovan, John Moult, Vincent A Fischetti, Frank Heinrich, Mathias Lösche, Daniel C Nelson   +13 more
openaire   +3 more sources

Enhanced antibacterial activity of Acinetobacter baumannii bacteriophage ØABP-01 endolysin (LysABP-01) in combination with colistin

Frontiers in Microbiology, 2016
Endolysins are lytic enzymes produced by bacteriophages with their ability to degrade the cell wall of bacterial hosts. Endolysin (LysABP-01) from A. baumannii bacteriophage ØABP-01 was cloned, overexpressed and characterized.
Rapee Thummeepak, Thawatchai Kitti, Duangkamol Kunthalert, Duangkamol Kunthalert, Sutthirat Sitthisak, Sutthirat Sitthisak   +5 more
doaj   +1 more source