Results 41 to 50 of about 8,598 (217)

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]

open access: yes, 2017
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves   +4 more
core   +1 more source

External lysis of Escherichia coli by a bacteriophage endolysin modified with hydrophobic amino acids

open access: yesAMB Express, 2019
Drug-resistant bacteria are a serious threat to global public health. Gram-positive bacterial endolysin preparations have been successfully used to fight Gram-positive bacteria as a novel antimicrobial replacement strategy.
Guangmou Yan   +8 more
doaj   +1 more source

Expression of a recombinant endolysin from bacteriophage CAP 10-3 with lytic activity against Cutibacterium acnes

open access: yesScientific Reports, 2023
The bacteriophage CAP 10-3 forming plaques against Cutibacterium acnes which causes skin acne was previously isolated from human skin acne lesion. Incomplete whole genome sequence (WGS) of the bacteriophage CAP 10-3 was obtained and it had 29,643 bp long
Ja-I Kim   +2 more
doaj   +1 more source

Insight into the Lytic Functions of the Lactococcal Prophage TP712 [PDF]

open access: yes, 2019
The lytic cassette of Lactococcus lactis prophage TP712 contains a putative membrane protein of unknown function (Orf54), a holin (Orf55), and a modular endolysin with a N-terminal glycoside hydrolase (GH_25) catalytic domain and two C-terminal LysM ...
Campelo, Ana Belén   +5 more
core   +1 more source

Endolysins against Streptococci as an antibiotic alternative

open access: yesFrontiers in Microbiology, 2022
Multi-drug resistance has called for a race to uncover alternatives to existing antibiotics. Phage therapy is one of the explored alternatives, including the use of endolysins, which are phage-encoded peptidoglycan hydrolases responsible for bacterial lysis.
Kuan Yee Wong   +6 more
openaire   +3 more sources

Potential of a novel and thermostable recombinant phage endolysin of Escherichia phage KW1E_UTAR against Shigella spp. [PDF]

open access: yesE3S Web of Conferences
Shigella causes millions of cases and hundreds of thousands of deaths annually, mainly affecting children in impoverished countries. Shigellosis outbreaks have been linked to waterborne transmission, and chlorination is commonly used to disinfect water ...
Selvam Dharshini   +2 more
doaj   +1 more source

Expression and delivery of an endolysin to combat Clostridium perfringens [PDF]

open access: yes, 2013
Clostridium perfringens is a cause for increasing concern due to its responsibility for severe infections both in humans and animals, especially poultry. To find new control strategies to treat C.
Arjan Narbad   +5 more
core   +1 more source

Endolysins of bacteriophage vB_Sal-S-S10 can naturally lyse Salmonella enteritidis

open access: yesBMC Veterinary Research, 2022
Background The holin-endolysin lysis system plays an essential role in the phage life cycle. Endolysins are promising alternatives to antibiotics, and have been successfully used against Gram-positive bacteria.
Xinrui Wang   +5 more
doaj   +1 more source

Prophage-triggered membrane vesicle formation through peptidoglycan damage in Bacillus subtilis [PDF]

open access: yes, 2017
Bacteria release membrane vesicles (MVs) that play important roles in various biological processes. However, the mechanisms of MV formation in Gram-positive bacteria are unclear, as these cells possess a single cytoplasmic membrane that is surrounded by ...
Cárcamo-Oyarce Gerardo   +11 more
core   +1 more source

Combination Effect of Engineered Endolysin EC340 With Antibiotics [PDF]

open access: yesFrontiers in Microbiology, 2022
Bacteriophage lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages during the final stage of the lytic cycle to enable cleavage through the host’s cell wall, thus allowing the phages to burst out of their host bacteria after multiplication inside them. When applied externally to Gram-negative bacteria
Hye-Won Hong   +8 more
openaire   +3 more sources

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