Results 31 to 40 of about 8,598 (217)
Endolysins as Antimicrobials [PDF]
, 2012 Peptidoglycan (PG) is the major structural component of the bacterial cell wall. Bacteria have autolytic PG hydrolases that allow the cell to grow and divide. A well-studied group of PG hydrolase enzymes are the bacteriophage endolysins. Endolysins are PG-degrading proteins that allow the phage to escape from the bacterial cell during the phage lytic ...
Nelson, Daniel C. +6 more
openaire +3 more sources
Frontiers in Microbiology, 2023 The advent of multidrug-resistant (MDR) bacteria poses a major threat to public health, garnering attention to novel antibiotic replacements. Endolysin, a bacteriophage-derived cell wall-degrading enzyme, is a promising alternative to conventional ...
Su Min Son +7 more
doaj +1 more source
Microbial Cell Factories, 2022 Background Salmonella is a common foodborne pathogen, which can cause intestinal diseases. In the last decades, the overuse of antibiotics has led to a pandemic of drug-resistant bacterial infections.
Shuhang Zhang +5 more
doaj +1 more source
Phage-derived peptidoglycan degrading enzymes: challenges and future prospects for in vivo therapy [PDF]
, 2018 Peptidoglycan degrading enzymes are of increasing interest as antibacterial agents, especially against multi-drug resistant pathogens. Herein we present a review about the biological features of virion-associated lysins and endolysins, phage-derived ...
Azeredo, Joana +2 more
core +5 more sources
Complete Genomic and Lysis-Cassette Characterization of the Novel Phage, KBNP1315, which Infects Avian Pathogenic Escherichia coli (APEC). [PDF]
PLoS ONE, 2015 Avian pathogenic Escherichia coli (APEC) is a major pathogen that causes avian colibacillosis and is associated with severe economic losses in the chicken-farming industry.
Jung Seok Lee +8 more
doaj +1 more source
A novel programmable lysozyme-based lysis system in Pseudomonas putida for biopolymer production [PDF]
, 2017 Indexación: Scopus; Web of Science.Cell lysis is crucial for the microbial production of industrial fatty acids, proteins, biofuels, and biopolymers. In this work, we developed a novel programmable lysis system based on the heterologous expression of ...
Borrero de Acuña, J.M. +4 more
core +1 more source
Scientific Reports, 2022 Bacteriophage endolysins degrade the bacterial cell wall and are therefore considered promising antimicrobial alternatives to fight pathogens resistant to conventional antibiotics. Gram-positive bacteria are usually considered easy targets to exogenously
Ana Gouveia +5 more
doaj +1 more source
Propionibacterium acnes bacteriophages display limited genetic diversity and broad killing activity against bacterial skin isolates. [PDF]
, 2012 UnlabelledInvestigation of the human microbiome has revealed diverse and complex microbial communities at distinct anatomic sites. The microbiome of the human sebaceous follicle provides a tractable model in which to study its dominant bacterial ...
Bowman, Charles +13 more
core +2 more sources
Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]
, 2017 The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core +1 more source
IgA-enhancing effects of membrane vesicles derived from Lactobacillus sakei subsp. sakei NBRC15893 [PDF]
, 2018 Immunoglobulin (Ig) A in the mucus of the intestinal tract plays an important role in preventing the invasion of pathogenic microorganisms and regulating the composition of the gut microbiota.
Katakura Yoshio +7 more
core +2 more sources