Results 11 to 20 of about 6,966 (163)
Potential of a novel and thermostable recombinant phage endolysin of Escherichia phage KW1E_UTAR against Shigella spp. [PDF]
E3S Web of ConferencesShigella causes millions of cases and hundreds of thousands of deaths annually, mainly affecting children in impoverished countries. Shigellosis outbreaks have been linked to waterborne transmission, and chlorination is commonly used to disinfect water ...
Selvam Dharshini +2 more
doaj +4 more sources
Frontiers in Microbiology, 2015 Maltocin P28 is a phage-tail like bacteriocin produced by Stenotrophomonas maltophilia P28. The ORF8 of maltocin P28 gene cluster is predicted to encode an endolysin and we name it endolysin P28.
Hongling eDong +5 more
doaj +2 more sources
Scientific Reports, 2023 The bacteriophage CAP 10-3 forming plaques against Cutibacterium acnes which causes skin acne was previously isolated from human skin acne lesion. Incomplete whole genome sequence (WGS) of the bacteriophage CAP 10-3 was obtained and it had 29,643 bp long
Ja-I Kim +2 more
doaj +2 more sources
VirusesBacteriophage-derived endolysins are being developed as an alternative to antimicrobials. The development of endolysins against Gram-negative bacteria requires the discovery of effective endolysins against the target species and the capability to ...
Masato Kogawa +7 more
doaj +2 more sources
Therapeutic Potential of an Endolysin Derived from Kayvirus S25-3 for Staphylococcal Impetigo
Viruses, 2019 Impetigo is a contagious skin infection predominantly caused by Staphylococcus aureus. Decontamination of S. aureus from the skin is becoming more difficult because of the emergence of antibiotic-resistant strains.
Ichiro Imanishi +7 more
doaj +2 more sources
Antibacterial activity of vB_AbaM_PhT2 phage hydrophobic amino acid fusion endolysin, combined with colistin against Acinetobacter baumannii [PDF]
Scientific Reports, 2023 Phage lytic enzymes are promising antimicrobial agents. In this study, an endolysin derived from vB_AbaM_PhT2 (vPhT2), was identified. This endolysin represented the conserved lysozyme domain.
Sutthirat Sitthisak +9 more
doaj +2 more sources
Polycationic Peptide Engineering of Phage Endolysins Expands Host Range and Enhances Antibacterial and Antibiofilm Activities Against Bacillus Species. [PDF]
Biotechnol BioengABSTRACT The exponential rise in antimicrobial resistance has highlighted the urgent need for the development of alternative antibacterial strategies, including phage‐derived and engineered protein agents such as endolysins and artilysins. In this study, we report the rational design, expression, and functional characterization of novel artilysins ...
Ansari F, Tarushi, Nagar V.
europepmc +2 more sources
Human Gut Phageome Analysis Uncovers Thousands of Highly Modular Endolysins. [PDF]
MicrobiologyopenAnalysis of 9141 human gut metagenomes identified 15,267 phage genomes and 3794 highly modular endolysins. The recovered endolysins showed remarkable catalytic and cell wall–binding domain diversity, highlighting the gut phageome as a rich source of novel enzybiotics with therapeutic potential against multidrug‐resistant bacteria.
Niloy RK +6 more
europepmc +2 more sources
Complete Genomic and Lysis-Cassette Characterization of the Novel Phage, KBNP1315, which Infects Avian Pathogenic Escherichia coli (APEC). [PDF]
PLoS ONE, 2015 Avian pathogenic Escherichia coli (APEC) is a major pathogen that causes avian colibacillosis and is associated with severe economic losses in the chicken-farming industry.
Jung Seok Lee +8 more
doaj +1 more source
AMB Express, 2019 Drug-resistant bacteria are a serious threat to global public health. Gram-positive bacterial endolysin preparations have been successfully used to fight Gram-positive bacteria as a novel antimicrobial replacement strategy.
Guangmou Yan +8 more
doaj +1 more source