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Bacteriophages and Food Production: Biocontrol and Bio-Preservation Options for Food Safety
Antibiotics, 2022 Food safety and sustainable food production is an important part of the Sustainable Development goals aiming to safeguard the health and wellbeing of humans, animals and the environment.
Mary Garvey
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Novel and emerging antimicrobial strategies in the management of oral infections
Periodontology 2000, EarlyView.Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
Table_1_Thousands of Novel Endolysins Discovered in Uncultured Phage Genomes.XLSX
, 2018 Bacteriophages express endolysins toward the end of their replication cycle to degrade the microbial cell wall from within, allowing viral progeny to be released. Endolysins can also degrade the prokaryotic cell wall from the outside, thus have potential
Iris Fernández-Ruiz (5235731) +2 more
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A novel activation mechanism for Clostridial bacteriophage endolysins [PDF]
, 2014 Bacteriophage-encoded endolysins are produced at the end of the phage lytic cycle for the degradation of the host bacterial cell. Endolysins offer the potential as alternatives to antibiotics as biocontrol agents or therapeutics.
Dunne, Matthew Stephen
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PhaLP: A Database for the Study of Phage Lytic Proteins and Their Evolution
Viruses, 2021 Phage lytic proteins are a clinically advanced class of novel enzyme-based antibiotics, so-called enzybiotics. A growing community of researchers develops phage lytic proteins with the perspective of their use as enzybiotics.
Bjorn Criel +4 more
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Comprehensive Physiology, Volume 16, Issue 6, December 2026.Schematic diagram illustrating the potential mechanisms and core molecules contributing to the development of PE via mediating pyroptosis: focus on trophoblasts and endothelial cells. Pyroptosis of trophoblast cells in the placenta of preeclampsia not only inhibits its invasion, migration, and differentiation, causing local infiltration and ...
Xianyi Zhou +5 more
wiley +1 more source
, 2023 The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in the dairy industry has become a fundamental concern. Endolysins are bacteriophage-derived peptidoglycan hydrolases that induce the rapid lysis of host bacteria. Herein, we
Jakyeom Seo, Hanbeen Kim
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Viruses, 2023 The number of infections caused by antibiotic-resistant strains of bacteria is growing by the year. The pathogenic bacterial species Enterococcus faecalis and Enterococcus faecium are among the high priority candidate targets for the development of new ...
Rustam M. Buzikov +4 more
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British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3448-3459, October 2026.Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen +13 more
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Scientific Reports, 2022 Bacteriophage endolysins degrade the bacterial cell wall and are therefore considered promising antimicrobial alternatives to fight pathogens resistant to conventional antibiotics. Gram-positive bacteria are usually considered easy targets to exogenously
Ana Gouveia +5 more
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