Results 71 to 80 of about 4,149 (194)

Mechanisms of Resistance, Insights From Case Reports, and Future Prospects in Mycobacteriophage Therapy

open access: yesJournal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.
Evolution of drug‐resistant mycobacterial infections warrants renewed efforts in identifying more efficient preventive and control strategies as well as alternative treatment options. Interest in phage therapy is regaining significant traction, especially in cases of failed conventional therapy.
Buhari Yusuf   +10 more
wiley   +1 more source

Molecular Aspects and Comparative Genomics of Bacteriophage Endolysins [PDF]

open access: yesJournal of Virology, 2013
ABSTRACT Phages are recognized as the most abundant and diverse entities on the planet. Their diversity is determined predominantly by their dynamic adaptation capacities when confronted with different selective pressures in an endless cycle of coevolution with a widespread group of bacterial hosts.
Oliveira, Hugo   +7 more
openaire   +4 more sources

Lack of improvement after short‐term topical antistaphylococcal endolysin SA.100 therapy in patients with mild‐to‐moderate atopic dermatitis: Results from a randomized, vehicle‐controlled trial

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2409-2413, July 2026.
Abstract Atopic dermatitis (AD) is a chronic immune‐mediated inflammatory skin disease. An overgrowth of Staphylococcus aureus (S. aureus) and decreased microbial diversity is apparent in 70%–90% of AD patients. SA.100 is a recombinant endolysin targeting S. aureus that might be a novel treatment for patients with mild‐to‐moderate AD.
Laura W. J. van der Meulen   +15 more
wiley   +1 more source

IDENTIFICATION AND ENGINEERING BACTERIOPHAGE ENDOLYSINS FOR INACTIVATION OF GRAM-POSITIVE SPORE-FORMING BACILLI

open access: yes, 2018
This dissertation concentrates on the study of the antibacterial potential of bacteriophage-encoded endolysins derived from phages that infect the Gram-positive Bacillus cereus sensu lato group.
Etobayeva, Irina V.
core   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

open access: yesInterdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma   +6 more
wiley   +1 more source

Bioinformatic Analysis of Prophage Endolysins and Endolysin-Like Genes from the Order Lactobacillales

open access: yesNova Biotechnologica et Chimica, 2012
Bioinformatic Analysis of Prophage Endolysins and Endolysin-Like Genes from the Order Lactobacillales Endolysins belonging to the group of peptigoglycan hydrolases, which are able to cleave peptidoglycan in bacterial cell walls, become an extensively studied group of enzymes.
Lenka Maliničová   +2 more
openaire   +1 more source

Identification and Genomic Analysis of the First Salmonella typhimurium Monophasic Variant 1,4,[5],12:i:‐ Isolate Harbouring a Chromosomally Integrated blaNDM‐5

open access: yesMicrobial Biotechnology, Volume 19, Issue 7, July 2026.
This study reports the first clinical isolate of the monophasic variant of Salmonella typhimurium (serotype 1,4,[5],12:i:‐) ST34 harbouring a chromosomally integrated blaNDM‐5. The ~11 kb resistance region is flanked by two directly oriented IS26 elements, forming an IS26‐composite transposon.
Shihan Zeng   +4 more
wiley   +1 more source

An Endolysin LysSE24 by Bacteriophage LPSE1 Confers Specific Bactericidal Activity against Multidrug-Resistant Salmonella Strains

open access: yesMicroorganisms, 2020
Salmonella is responsible for a wide range of infections and is a constant threat to public health, particularly in light of emerging antibiotic resistance.
Yifeng Ding   +4 more
doaj   +1 more source

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

open access: yesAllergy, Volume 81, Issue 7, Page 2435-2449, July 2026.
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud   +23 more
wiley   +1 more source

Summary of enzymatic activity of phage-derived endolysins of the phages of this study.

open access: yes, 2019
Summary of enzymatic activity of phage-derived endolysins of the phages of this study.
Manfred Rohde (61075)   +7 more
core   +1 more source

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