Results 71 to 80 of about 4,149 (194)
Evolution of drug‐resistant mycobacterial infections warrants renewed efforts in identifying more efficient preventive and control strategies as well as alternative treatment options. Interest in phage therapy is regaining significant traction, especially in cases of failed conventional therapy.
Buhari Yusuf +10 more
wiley +1 more source
Molecular Aspects and Comparative Genomics of Bacteriophage Endolysins [PDF]
ABSTRACT Phages are recognized as the most abundant and diverse entities on the planet. Their diversity is determined predominantly by their dynamic adaptation capacities when confronted with different selective pressures in an endless cycle of coevolution with a widespread group of bacterial hosts.
Oliveira, Hugo +7 more
openaire +4 more sources
Abstract Atopic dermatitis (AD) is a chronic immune‐mediated inflammatory skin disease. An overgrowth of Staphylococcus aureus (S. aureus) and decreased microbial diversity is apparent in 70%–90% of AD patients. SA.100 is a recombinant endolysin targeting S. aureus that might be a novel treatment for patients with mild‐to‐moderate AD.
Laura W. J. van der Meulen +15 more
wiley +1 more source
This dissertation concentrates on the study of the antibacterial potential of bacteriophage-encoded endolysins derived from phages that infect the Gram-positive Bacillus cereus sensu lato group.
Etobayeva, Irina V.
core +1 more source
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma +6 more
wiley +1 more source
Bioinformatic Analysis of Prophage Endolysins and Endolysin-Like Genes from the Order Lactobacillales Endolysins belonging to the group of peptigoglycan hydrolases, which are able to cleave peptidoglycan in bacterial cell walls, become an extensively studied group of enzymes.
Lenka Maliničová +2 more
openaire +1 more source
This study reports the first clinical isolate of the monophasic variant of Salmonella typhimurium (serotype 1,4,[5],12:i:‐) ST34 harbouring a chromosomally integrated blaNDM‐5. The ~11 kb resistance region is flanked by two directly oriented IS26 elements, forming an IS26‐composite transposon.
Shihan Zeng +4 more
wiley +1 more source
Salmonella is responsible for a wide range of infections and is a constant threat to public health, particularly in light of emerging antibiotic resistance.
Yifeng Ding +4 more
doaj +1 more source
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud +23 more
wiley +1 more source
Summary of enzymatic activity of phage-derived endolysins of the phages of this study.
Summary of enzymatic activity of phage-derived endolysins of the phages of this study.
Manfred Rohde (61075) +7 more
core +1 more source

