Results 61 to 70 of about 4,149 (194)

Genomic and Phenotypic Characterization of Two Novel Enterobacter Phages With EDTA‐Enhanced Antibiofilm Activity

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Two novel lytic Enterobacter phages, HHH and RZH, displayed targeted antibiofilm activity against MDR Enterobacter cloacae complex biofilms when combined with EDTA. Activity was strongest within a narrow low‐millimolar EDTA window, reducing biofilm biomass and viable burden, while higher EDTA concentrations shifted the interaction towards antagonism ...
Kashif Haq   +4 more
wiley   +1 more source

Regulation of a Phage Endolysin by Disulfide Caging [PDF]

open access: yesJournal of Bacteriology, 2010
ABSTRACT In contrast to canonical phage endolysins, which require holin-mediated disruption of the membrane to gain access to attack the cell wall, signal anchor release (SAR) endolysins are secreted by the host sec system, where they accumulate in an inactive form tethered to the membrane by their N ...
Gabriel F, Kuty   +4 more
openaire   +2 more sources

Mechanisms and Application of Bacteriophages in Regulating Intestinal Health of Livestock and Poultry

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Bacteriophages offer targeted, self‐limiting control of intestinal pathogens in livestock and poultry. This review integrates their biological properties, mechanisms of gut‐health promotion, key experimental evidence, application strategies, and current challenges, outlining a path toward sustainable animal production and global food security ...
Manman Song   +6 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Investigation of bacteriophage endolysins activity. [PDF]

open access: yes, 2019
Because of rapid growth of bacterial resistance to various antibiotics, it is necessary to discover alternatives to kill bacteria. Bacteriophages were considered as an opportunity for long time, but since bacteria also became resistant to them, attention
Cicilionytė, Aurelija,
core  

Simultaneous Control of Staphylococcus aureus and Bacillus cereus Using a Hybrid Endolysin LysB4EAD-LysSA11

open access: yesAntibiotics, 2020
Bacteriophage endolysins have attracted attention as promising alternatives to antibiotics, and their modular structure facilitates endolysin engineering to develop novel endolysins with enhanced versatility.
Bokyung Son   +4 more
doaj   +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

open access: yesBiotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen   +2 more
wiley   +1 more source

Diversity of Endolysin Domain Architectures in Bacteriophages Infecting Bacilli

open access: yesBiomolecules
The increasing number of antibiotic-resistant bacterial pathogens is a serious problem in medicine. Endolysins are bacteriolytic enzymes of bacteriophages, and a promising group of enzymes with antibacterial properties.
Olga N. Koposova   +2 more
doaj   +1 more source

Revisiting Burn Wound Infections: A Comprehensive Review on the Dual Potential of Phages and Probiotics Against Acinetobacter baumannii

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 16, August 2026.
Effect Probiotics on immune system modulation and wound Healing. ABSTRACT Introduction Burn wound infections caused by Acinetobacter baumannii remain a critical clinical challenge due to its extensive multidrug resistance, particularly against carbapenems.
Zeinab Fagheei Aghmiyuni   +6 more
wiley   +1 more source

Regenerative Microbiology: Harnessing Bacterial Antagonism and Spatiotemporal Signaling for Diabetic Wound Repair

open access: yesSmart Medicine, Volume 5, Issue 4, August 2026.
This review introduces “Regenerative Microbiology,” a framework that uses bacterial antagonism and phage therapy to address diabetic wound dysbiosis. By activating the p40/EGFR/PI3K axis and providing a vascular‐stratified precision roadmap, this approach shifts the paradigm from antimicrobial suppression to intelligent, microbe‐driven tissue ...
Sabri Saeed Sanabani
wiley   +1 more source

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