Results 81 to 90 of about 4,149 (194)
, 2022 (A) Analysis of non-lactococcal phages that have endolysins with at least 90% coverage and 50% identity to endolysins of lactococcal phages (S7 Data). B) Analysis of non-lactococcal phage genomes with at least 1,000-bp homology with lactococcal phages. L.
Xiaojun Zhu (352546) +4 more
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Zdorovʹe Rebenka, 2017 Bacteriophages are viruses that, due to the receptor/ligand interactions, are able to specifically bind to the bacterial wall and replicate within specific bacteria.
А.Е. Abaturov, Т.А. Kryuchko
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Host-Endolysins interactions [PDF]
, 2013 37 Host-Endolysins interactions Franklin L. Nobrega, Silvio Santos, Eugénio C. Ferreira, Joana Azeredo, Leon D. Kluskens IBB – Institute for Biotechnology and Bioengineering, Centre of Biological Engineering, Universidade do Minho, Campus de Gualtar ...
Ferreira, Eugénio C. +4 more
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Biochemistry and Biophysics ReportsStreptococcus pneumoniae (pneumococcus) is a multidrug-resistant pathogen associated with pneumonia, otitis media, meningitis and other severe complications that are currently a global threat to human health.
Tahsin Khan +7 more
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Bacteriophage endolysins--current state of research and applications.
, 2005 Endolysins are phage-encoded enzymes that break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. Their action is tightly regulated by holins, by membrane arrest, and by conversion from their inactive to active state ...
Loessner MJ
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AMB Express, 2019 Drug-resistant bacteria are a serious threat to global public health. Gram-positive bacterial endolysin preparations have been successfully used to fight Gram-positive bacteria as a novel antimicrobial replacement strategy.
Guangmou Yan +8 more
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A bacteriophage endolysin that eliminates intracellular streptococci
eLife, 2016 PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling intracellular Spy that often underlies refractory infections. We show that the PlyC holoenzyme, mediated by its PlyCB subunit, crosses epithelial cell membranes and clears intracellular Spy in a dose ...
Yang Shen +13 more
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From endolysins to Artilysin ® s: novel enzyme-based approaches to kill drug-resistant bacteria [PDF]
, 2020 One of the last untapped reservoirs in nature for the identification of new anti-microbials is bacteriophages, the natural killers of bacteria. Lytic bacteriophages encode peptidoglycan (PG) lytic enzymes able to degrade the PG layer in different steps ...
Yves Briers +3 more
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Effective Removal of Staphylococcal Biofilms by the Endolysin LysH5
PLoS ONE, 2014 Staphylococcal biofilms are a major concern in both clinical and food settings because they are an important source of contamination. The efficacy of established cleaning procedures is often hindered due to the ability of some antimicrobial compounds to induce biofilm formation, and to the presence of persister cells, a small bacterial subpopulation ...
Diana Gutiérrez +4 more
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Bacteriophage endolysins as a potential weapon to combat Clostridioides difficile infection
, 2020 Clostridioides difficile is the leading cause of health-care-associated infection throughout the developed world and contributes significantly to patient morbidity and mortality. Typically, antibiotics are used for the primary treatment of C.
Hill, Colin +7 more
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