Results 11 to 20 of about 55,351 (242)

Flap Endonuclease 1 [PDF]

open access: yesAnnual Review of Biochemistry, 2013
First discovered as a structure-specific endonuclease that evolved to cut at the base of single-stranded flaps, flap endonuclease (FEN1) is now recognized as a central component of cellular DNA metabolism. Substrate specificity allows FEN1 to process intermediates of Okazaki fragment maturation, long-patch base excision repair, telomere maintenance ...
Lata, Balakrishnan, Robert A, Bambara
openaire   +2 more sources

Crystal structures of Lymphocytic choriomeningitis virus endonuclease domain complexed with diketo-acid ligands

open access: yesIUCrJ, 2018
The Arenaviridae family, together with the Bunyaviridae and Orthomyxoviridae families, is one of the three negative-stranded RNA viral families that encode an endonuclease in their genome.
Magali Saez-Ayala   +5 more
doaj   +1 more source

Variabilidade genética na região its do rDNA de isolados de trichoderma spp. (Biocontrolador) e Fusarium oxysporum f. sp. Chrysanthemi Genetic variability in rDNA ITS region of Trichoderma spp. (biocontrole agent) and Fusarium oxysporum f. sp. chrysanthemi isolates

open access: yesCiência e Agrotecnologia, 2010
A análise de características morfológicas e culturais podem não ser suficientes para uma caracterização precisa das espécies de Trichoderma e Fusarium.
Josiane Pacheco Menezes   +5 more
doaj   +1 more source

Historical Aspects of Restriction Endonucleases as Intelligent Scissors for Genetic Engineering

open access: yesFermentation, 2023
Restriction endonucleases are a component of restriction–modification systems, where the main biological function is to protect bacterial cells from incoming foreign DNA molecules.
Irina V. Alekseeva, Nikita A. Kuznetsov
doaj   +1 more source

Characterization of immobilized biomass by amplified rDNA restriction analysis (ARDRA) in an anaerobic sequencing-batch biofilm reactor (ASBBR) for the treatment of industrial wastewater

open access: yesBrazilian Archives of Biology and Technology, 2012
The performance of an anaerobic sequencing-batch biofilm reactor (ASBBR- laboratory scale- 14L )containing biomass immobilized on coal was evaluated for the removal of elevated concentrations of sulfate (between 200 and 3,000 mg SO4-2·L-1) from ...
Arnaldo Sarti   +2 more
doaj   +1 more source

Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

open access: yesBiomolecules, 2018
Ribosomal RNAs, the most abundant cellular RNA species, have evolved as the structural scaffold and the catalytic center of protein synthesis in every living organism.
Maxime Aubert   +3 more
doaj   +1 more source

Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BmoI. [PDF]

open access: yesPLoS ONE, 2011
Homing endonucleases are site-specific DNA endonucleases that function as mobile genetic elements by introducing double-strand breaks or nicks at defined locations.
Benjamin P Kleinstiver   +3 more
doaj   +1 more source

Enzymatic cleavage of type II restriction endonucleases on the 2'-O-methyl nucleotide and phosphorothioate substituted DNA. [PDF]

open access: yesPLoS ONE, 2013
The effects of nucleotide analogue substitution on the cleavage efficiencies of type II restriction endonucleases have been investigated. Six restriction endonucleases (EcoRV, SpeI, XbaI, XhoI, PstI and SphI) were investigated respectively regarding ...
Guojie Zhao   +5 more
doaj   +1 more source

New Insights Into DNA Repair Revealed by NucS Endonucleases From Hyperthermophilic Archaea

open access: yesFrontiers in Microbiology, 2020
Hyperthermophilic Archaea (HA) thrive in high temperature environments and their genome is facing severe stability challenge due to the increased DNA damage levels caused by high temperature.
Likui Zhang   +5 more
doaj   +1 more source

Viral Nucleases

open access: yesViruses, 2023
Nucleases are ubiquitous hydrolytic enzymes that cleave phosphodiester bond of DNA (DNases), RNA (RNases), or protein-RNA/DNA (phosphodiesterases), within the strand (endonucleases) or from the end (exonucleases) [...]
Zhengqiang Wang, Robert J. Geraghty
doaj   +1 more source

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