Results 11 to 20 of about 155,310 (382)

Sequence-specific DNA nicking endonucleases

open access: yesBiomolecular Concepts, 2015
A group of small HNH nicking endonucleases (NEases) was discovered recently from phage or prophage genomes that nick double-stranded DNA sites ranging from 3 to 5 bp in the presence of Mg2+ or Mn2+.
Xu Shuang-yong
doaj   +2 more sources

The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases

open access: greenScience, 2021
Description Tracing the origin of CRISPR-Cas CRISPR-Cas systems have transformed genome editing and other biotechnologies; however, the broader origins and diversity of RNA-guided nucleases have largely remained unexplored. Altae-Tran et al.
Han Altae-Tran   +11 more
openalex   +3 more sources

DNA Tetrahedra Modules as Versatile Optical Sensing Platforms for Multiplexed Analysis of miRNAs, Endonucleases, and Aptamer–Ligand Complexes

open access: yesACS Nano, 2020
The sensing modules for analyzing miRNAs or the endonucleases consist of tetrahedra functionalized with three different fluorophore–quencher pairs in spatially quenched configurations and hairpin units acting as recognition elements for the analytes ...
Zhixin Zhou   +3 more
semanticscholar   +1 more source

The Coevolution of Fungal Mitochondrial Introns and Their Homing Endonucleases (GIY-YIG and LAGLIDADG)

open access: yesGenome Biology and Evolution, 2020
Fungal mitochondrial (mt) genomes exhibit great diversity in size which is partially attributed to their variable intergenic regions and most importantly to the inclusion of introns within their genes.
Amalia H Megarioti, V. Kouvelis
semanticscholar   +1 more source

Molecular variation of Trypanosoma brucei subspecies as revealed by AFLP fingerprinting [PDF]

open access: yes, 2002
Genetic analysis of Trypanosoma spp. depends on the detection of variation between strains. We have used the amplified fragment length polymorphism (AFLP) technique to develop a convenient and reliable method for genetic characterization of Trypanosome ...
Agbo, E.E.C.   +3 more
core   +9 more sources

Genotyping with CRISPR-Cas-derived RNA-guided endonucleases [PDF]

open access: bronzeNature Communications, 2014
Jong Min Kim   +3 more
openalex   +2 more sources

Isolation, cloning and molecular characterization of genes encoding single-strand specific endonucleases from Parsley (Petroselinum crispum L.) [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2015
Single-strand specific (sss) nucleases (S1/P1 family) are widely used in molecular genetics studies. The most widely used sss-nucleases are those plant endonucleases with the ability of specific cleavage of mismatch loops in heteroduplex DNA molecules ...
Mahdiyeh Mirzaei   +2 more
doaj   +1 more source

Flap Endonuclease 1 [PDF]

open access: yesAnnual Review of Biochemistry, 2013
First discovered as a structure-specific endonuclease that evolved to cut at the base of single-stranded flaps, flap endonuclease (FEN1) is now recognized as a central component of cellular DNA metabolism. Substrate specificity allows FEN1 to process intermediates of Okazaki fragment maturation, long-patch base excision repair, telomere maintenance ...
Lata, Balakrishnan, Robert A, Bambara
openaire   +2 more sources

Crystal structures of Lymphocytic choriomeningitis virus endonuclease domain complexed with diketo-acid ligands

open access: yesIUCrJ, 2018
The Arenaviridae family, together with the Bunyaviridae and Orthomyxoviridae families, is one of the three negative-stranded RNA viral families that encode an endonuclease in their genome.
Magali Saez-Ayala   +5 more
doaj   +1 more source

Editosome Accessory Factors KREPB9 and KREPB10 in Trypanosoma brucei [PDF]

open access: yes, 2012
Multiprotein complexes, called editosomes, catalyze the uridine insertion and deletion RNA editing that forms translatable mitochondrial mRNAs in kinetoplastid parasites.
Acestor   +58 more
core   +1 more source

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