Results 11 to 20 of about 55,351 (242)
First discovered as a structure-specific endonuclease that evolved to cut at the base of single-stranded flaps, flap endonuclease (FEN1) is now recognized as a central component of cellular DNA metabolism. Substrate specificity allows FEN1 to process intermediates of Okazaki fragment maturation, long-patch base excision repair, telomere maintenance ...
Lata, Balakrishnan, Robert A, Bambara
openaire +2 more sources
The Arenaviridae family, together with the Bunyaviridae and Orthomyxoviridae families, is one of the three negative-stranded RNA viral families that encode an endonuclease in their genome.
Magali Saez-Ayala +5 more
doaj +1 more source
A análise de características morfológicas e culturais podem não ser suficientes para uma caracterização precisa das espécies de Trichoderma e Fusarium.
Josiane Pacheco Menezes +5 more
doaj +1 more source
Historical Aspects of Restriction Endonucleases as Intelligent Scissors for Genetic Engineering
Restriction endonucleases are a component of restriction–modification systems, where the main biological function is to protect bacterial cells from incoming foreign DNA molecules.
Irina V. Alekseeva, Nikita A. Kuznetsov
doaj +1 more source
The performance of an anaerobic sequencing-batch biofilm reactor (ASBBR- laboratory scale- 14L )containing biomass immobilized on coal was evaluated for the removal of elevated concentrations of sulfate (between 200 and 3,000 mg SO4-2·L-1) from ...
Arnaldo Sarti +2 more
doaj +1 more source
Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases
Ribosomal RNAs, the most abundant cellular RNA species, have evolved as the structural scaffold and the catalytic center of protein synthesis in every living organism.
Maxime Aubert +3 more
doaj +1 more source
Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BmoI. [PDF]
Homing endonucleases are site-specific DNA endonucleases that function as mobile genetic elements by introducing double-strand breaks or nicks at defined locations.
Benjamin P Kleinstiver +3 more
doaj +1 more source
Enzymatic cleavage of type II restriction endonucleases on the 2'-O-methyl nucleotide and phosphorothioate substituted DNA. [PDF]
The effects of nucleotide analogue substitution on the cleavage efficiencies of type II restriction endonucleases have been investigated. Six restriction endonucleases (EcoRV, SpeI, XbaI, XhoI, PstI and SphI) were investigated respectively regarding ...
Guojie Zhao +5 more
doaj +1 more source
New Insights Into DNA Repair Revealed by NucS Endonucleases From Hyperthermophilic Archaea
Hyperthermophilic Archaea (HA) thrive in high temperature environments and their genome is facing severe stability challenge due to the increased DNA damage levels caused by high temperature.
Likui Zhang +5 more
doaj +1 more source
Nucleases are ubiquitous hydrolytic enzymes that cleave phosphodiester bond of DNA (DNases), RNA (RNases), or protein-RNA/DNA (phosphodiesterases), within the strand (endonucleases) or from the end (exonucleases) [...]
Zhengqiang Wang, Robert J. Geraghty
doaj +1 more source

