Results 221 to 230 of about 65,125 (289)

Current Non-Viral-Based Strategies to Manufacture CAR-T Cells. [PDF]

Int J Mol Sci
Gehrke L, Gonçalves VDR, Andrae D, Rasko T, Ho P, Einsele H, Hudecek M, Friedel SR.   +7 more
europepmc   +1 more source

Comprehensive genetic and epigenetic characterization of Lynch‐like syndrome patients

International Journal of Cancer, Volume 157, Issue 4, Page 788-799, 15 August 2025.
What's new? Lynch‐like syndrome is associated with development of colorectal cancer (CRC) with microsatellite instability and loss of expression of certain mismatch repair (MMR) genes, similar to Lynch syndrome, but unlike Lynch syndrome, the genetic cause of Lynch‐like syndrome (LLS) remains unknown.
Francesca Pirini, Luciano Calzari, Gianluca Tedaldi, Michela Tebaldi, Valentina Zampiga, Ilaria Cangini, Rita Danesi, Mila Ravegnani, Valentina Arcangeli, Alessandro Passardi, Elisabetta Petracci, Sara Bravaccini, Giorgia Marisi, Alessandra Viel, Daniela Barana, Monica Pedroni, Luca Roncucci, Daniele Calistri, Davide Gentilini   +18 more
wiley   +1 more source

Expression of the <i>Nicotiana benthamiana</i> Retrozyme 1 (NbRZ1) Genomic Locus. [PDF]

Plants (Basel)
Lezzhov AA, Atabekova AK, Chergintsev DA, Solovyev AG, Morozov SY.   +4 more
europepmc   +1 more source

Linker‐mediated domain separation enhances cold adaptation in cellulases

Protein Science, Volume 34, Issue 8, August 2025.
Abstract Cold‐adapted cellulases have the potential to reduce energy demands in industrial processes by enabling efficient cellulose saccharification at lower temperatures. However, the structural basis of cold adaptation in bidomain cellulases remains poorly understood. Our prior studies on bidomain amylases proposed a “linker spacer effect”—a greater
Robbie Ge, Ning Ding, Yaoyukun Jiang, Zhongyue J. Yang   +3 more
wiley   +1 more source

Discovery of the widespread site-specific single-stranded nuclease family Ssn. [PDF]

Nat Commun
Chenal M, Rivera-Millot A, Harrison LB, Khairalla AS, Nieves C, Bernet È, Esmaili M, Belkhir M, Perreault J, Veyrier FJ.   +9 more
europepmc   +1 more source

Evaluating the Benefits and Limits of Multiple Displacement Amplification With Whole‐Genome Oxford Nanopore Sequencing

Molecular Ecology Resources, Volume 25, Issue 6, August 2025.
ABSTRACT Multiple displacement amplification (MDA) outperforms conventional PCR in long fragment and whole‐genome amplification, making it attractive to couple MDA with long‐read sequencing of samples with limited quantities of DNA to obtain improved genome assemblies.
Fiifi Agyabeng‐Dadzie, Megan S. Beaudry, Alex Deyanov, Haley Slanis, Minh Q. Duong, Randi Turner, Asis Khan, Cesar A. Arias, Jessica C. Kissinger, Travis C. Glenn, Rodrigo de Paula Baptista   +10 more
wiley   +1 more source

Editorial: Gene therapy and genome editing for metabolic liver disorders. [PDF]

Front Mol Med
Collaud F, Bortolussi G.
europepmc   +1 more source

Effective target genes for RNA interference‐based management of the cabbage stem flea beetle

Insect Molecular Biology, Volume 34, Issue 4, Page 527-539, August 2025.
An oral RNAi screen consisting of 27 dsRNAs identified effective target genes for RNAi‐based pest control in the cabbage stem flea beetle The most effective target genes were involved in proteasomal pathways or gene expression, and their sequences were subjected to in silico off‐target analysis Knock‐down of some effective target genes also inhibited ...
Doga Cedden, Gözde Güney, Xavier Debaisieux, Stefan Scholten, Michael Rostás, Gregor Bucher   +5 more
wiley   +1 more source

Role of DNase I in DNA degradation and cell-free DNA generation after acetaminophen-induced hepatic injury. [PDF]

J Vet Med Sci
Takada S, Ogawa S, Mizuta R.
europepmc   +1 more source

Environmental factors affecting RNAi efficacy: Temperature but not plant cultivar influences Colorado potato beetle's response to insecticidal dsRNA

Insect Molecular Biology, Volume 34, Issue 4, Page 581-592, August 2025.
Colorado potato beetle's RNA interference (RNAi) response was enhanced when insecticidal dsactin was consumed at high temperatures. The enhanced RNAi outcomes at high temperatures were not a function of dose or the expression of core RNAi genes. The potato cultivar consumed by Colorado potato beetle larvae did not affect RNAi outcomes, but larvae did ...
Mike Darrington, Jason Solocinski, Sophia K. Zhou, Melise C. Lecheta, Subba Reddy Palli, Yolanda H. Chen, Nicholas M. Teets   +6 more
wiley   +1 more source