Results 21 to 30 of about 55,351 (242)
BMC Microbiology, 2018 Background The functioning of DNA repair systems is based on correct interactions between proteins involved in DNA repair. Very Short Patch (VSP) repair is a DNA repair system that corrects mismatches resulting from the deamination of 5-methylcytosine ...
Monika Adamczyk-Popławska +2 more
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Mobile DNA elements in T4 and related phages
Virology Journal, 2010 Mobile genetic elements are common inhabitants of virtually every genome where they can exert profound influences on genome structure and function in addition to promoting their own spread within and between genomes.
Belfort Marlene +2 more
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Genes and Environment, 2017 Apurinic/apyrimidinic (AP) sites are one of the most frequent DNA lesions. AP sites inhibit transcription and DNA replication, and induce cell death. AP endonucleases are key enzymes in AP site repair. Several types of AP endonucleases have been reported,
Masafumi Funakoshi +3 more
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Frontiers in Microbiology, 2022 Strand-specific DNA nicking endonucleases (NEases) typically nick 3–7 bp sites. Our goal is to engineer infrequent NEase with a >8 bp recognition sequence.
Shuang-yong Xu
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Two restriction endonucleases [PDF]
Biochemistry and Molecular Biology Education, 2006 AbstractTerms to be familiar with before you start to solve the test: restriction endonucleases; palindromic sequences; blunt ends; cohesive (“sticky”) ends; in vitro DNA synthesis; radioactive nucleotide precursors; template‐primer complexes; DNA ligation.
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Sequence-specific DNA nicking endonucleases
Biomolecular Concepts, 2015 A group of small HNH nicking endonucleases (NEases) was discovered recently from phage or prophage genomes that nick double-stranded DNA sites ranging from 3 to 5 bp in the presence of Mg2+ or Mn2+.
Xu Shuang-yong
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Structure-Specific Endonucleases in DNA Repair
CHIMIA, 2009 Nucleotide excision repair (NER) is an essential DNA repair pathway that addresses a variety of DNA lesions formed by UV light, environmental mutagens and agents used in cancer chemotherapy.
Orlando D. Schärer
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F-CphI represents a new homing endonuclease family using the Endo VII catalytic motif
Mobile DNA, 2018 Background There are six known families of homing endonucleases, LAGLIDADG, GIY-YIG, HNH, His-Cys box, PD-(D/E)-XK, and EDxHD, which are characterized by their conserved residues.
Xiaoting Fang +3 more
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Frontiers in Microbiology, 2020 Modification dependent restriction endonucleases (MDREs) restrict modified DNA, typically with limited sequence specificity (∼2–4 bp). Here, we focus on MDREs that have an SRA and/or SBD (sulfur binding domain) fused to an HNH endonuclease domain ...
Thomas Lutz +10 more
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SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
Cell Reports, 2013 SLX4 interacts with several endonucleases to resolve structural barriers in DNA metabolism. SLX4 also interacts with telomeric protein TRF2 in human cells. The molecular mechanism of these interactions at telomeres remains unknown.
Bingbing Wan +13 more
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