Results 21 to 30 of about 106,966 (240)
Editosome Accessory Factors KREPB9 and KREPB10 in Trypanosoma brucei [PDF]
Multiprotein complexes, called editosomes, catalyze the uridine insertion and deletion RNA editing that forms translatable mitochondrial mRNAs in kinetoplastid parasites.
Acestor+58 more
core +1 more source
Enzymatic cleavage of type II restriction endonucleases on the 2'-O-methyl nucleotide and phosphorothioate substituted DNA. [PDF]
The effects of nucleotide analogue substitution on the cleavage efficiencies of type II restriction endonucleases have been investigated. Six restriction endonucleases (EcoRV, SpeI, XbaI, XhoI, PstI and SphI) were investigated respectively regarding ...
Guojie Zhao+5 more
doaj +1 more source
Labeling of Unique Sequences in Double-Stranded DNA at Sites of Vicinal Nicks Generated by Nicking Endonucleases [PDF]
We describe a new approach for labeling of unique sequences within dsDNA under nondenaturing conditions. The method is based on the site-specific formation of vicinal nicks, which are created by nicking endonucleases (NEases) at specified DNA sites on ...
Frank-Kamenetskii, Maxim D., Kuhn, Heiko
core +3 more sources
Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases
Ribosomal RNAs, the most abundant cellular RNA species, have evolved as the structural scaffold and the catalytic center of protein synthesis in every living organism.
Maxime Aubert+3 more
doaj +1 more source
Molecular evolution and morphological speciation in North Atlantic brachiopods (Terebratulina spp.) [PDF]
Morphological and molecular differentiation of western and eastern North Atlantic brachiopods were examined by morphometric analysis of six shell characteristics (<i>n</i>= 144), allozyme electrophoresis at six nuclear gene loci (<i>n ...
Balfe, P.+3 more
core +1 more source
Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BmoI. [PDF]
Homing endonucleases are site-specific DNA endonucleases that function as mobile genetic elements by introducing double-strand breaks or nicks at defined locations.
Benjamin P Kleinstiver+3 more
doaj +1 more source
New Insights Into DNA Repair Revealed by NucS Endonucleases From Hyperthermophilic Archaea
Hyperthermophilic Archaea (HA) thrive in high temperature environments and their genome is facing severe stability challenge due to the increased DNA damage levels caused by high temperature.
Likui Zhang+5 more
doaj +1 more source
Nucleases are ubiquitous hydrolytic enzymes that cleave phosphodiester bond of DNA (DNases), RNA (RNases), or protein-RNA/DNA (phosphodiesterases), within the strand (endonucleases) or from the end (exonucleases) [...]
Zhengqiang Wang, Robert J. Geraghty
doaj +1 more source
Introns interrupt the continuity of many eukaryal genes, and therefore their removal by splicing is a crucial step in gene expression. Interestingly, even within Eukarya there are at least four splicing mechanisms.
Abelson, John+2 more
core +1 more source
Background The functioning of DNA repair systems is based on correct interactions between proteins involved in DNA repair. Very Short Patch (VSP) repair is a DNA repair system that corrects mismatches resulting from the deamination of 5-methylcytosine ...
Monika Adamczyk-Popławska+2 more
doaj +1 more source