Results 111 to 120 of about 20,878 (232)

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, Volume 183, Issue 9, Page 2099-2122, May 2026.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Genetically stratified Parkinson’s disease with freezing of gait is related to specific pattern of cognitive impairment and non-motor dominant endophenotype

Frontiers in Aging Neuroscience
BackgroundFreezing of gait (FOG) is an important milestone in the individual disease trajectory of people with Parkinson’s disease (PD). Based on the cognitive model of FOG etiology, the mechanism behind FOG implies higher executive dysfunction in PDFOG+.
Lukas Pavelka, Lukas Pavelka, Lukas Pavelka, Rajesh Rawal, Stefano Sapienza, Jochen Klucken, Jochen Klucken, Jochen Klucken, Claire Pauly, Claire Pauly, Claire Pauly, Venkata Satagopam, Rejko Krüger, Rejko Krüger, Rejko Krüger   +14 more
doaj   +1 more source

Theta Power at 10 Months of Age Predicts Developmental Change in Language in Infants With and Without an Elevated Likelihood for Autism

Developmental Science, Volume 29, Issue 3, May 2026.
ABSTRACT Infants with an Elevated Likelihood (EL) for autism are more likely to experience language delays, but their language developmental trajectories are highly heterogeneous. The neurodevelopmental processes driving this variability remain unclear, yet understanding them is important for parsing the heterogeneity in language and informing earlier ...
Eirini Papageorgopoulou, Jannath Begum Ali, Greg Pasco, Amy Goodwin, Luke Mason, Mark H. Johnson, Tony Charman, Kalinka Timmer, Emily J. H. Jones, STAARS team   +9 more
wiley   +1 more source

Animals models of maladaptive traits: Disorders in sensorimotor gating and attentional quantifiable responses as possible endophenotypes

Frontiers in Psychology, 2016
Traditional diagnostic scales are based on a number of symptoms to evaluate and classify mental diseases. In many cases, this process becomes subjective, since the patient must calibrate the magnitude of his/her symptoms and therefore the severity of his/
Juan Pedro Vargas, Estrella eDiaz, Manuel ePortavella, Juan Carlos López   +3 more
doaj   +1 more source

Neural endophenotypes of social behaviour in autism spectrum conditions [PDF]

, 2011
Autism is characterized by qualitative impairments in social interaction, communication, and stereotyped repetitive behaviors and/or restricted interests.
Baron-Cohen, S, Belmonte, MK, Chakrabarti, B, Lombardo, MV   +3 more
core  

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries. [PDF]

, 2020
This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease.
Adhikari, Bhim M, Agartz, Ingrid, Aghajani, Moji, Aleman, André, Althoff, Robert R, Altmann, Andre, Andreassen, Ole A, Baron, David A, Bartnik-Olson, Brenda L, Baskin-Sommers, Arielle R, Baune, Bernhard T, Bearden, Carrie E, Berner, Laura A, Bertolín, Sara, Boedhoe, Premika SW, Bralten, Janita, Bright, Joanna, Brouwer, Rachel M, Bruin, Willem B, Buitelaar, Jan K, Bülow, Robin, Caeyenberghs, Karen, Cecil, Charlotte AM, Chen, Jian, Ching, Christopher RK, Chye, Yann, Cohen, Ronald A, Cole, James H, Conrod, Patricia J, Dannlowski, Udo, De Brito, Stephane A, de Kovel, Carolien GF, de Zwarte, Sonja MC, Dennis, Emily L, Desrivieres, Sylvane, Dima, Danai, Donohoe, Gary, Ehrlich, Stefan, Esopenko, Carrie, Eyler, Lisa T, Fairchild, Graeme, Faraone, Stephen V, Favre, Pauline, Filippi, Courtney A, Fisher, Simon E, Fouche, Jean-Paul, Francks, Clyde, Frodl, Thomas, Garijo, Daniel, Gil, Yolanda, Grabe, Hans J, Grasby, Katrina L, Hajek, Tomas, Han, Laura KM, Hatton, Sean N, Hilbert, Kevin, Ho, Tiffany C, Holleran, Laurena, Homuth, Georg, Hosten, Norbert, Houenou, Josselin, Ivanov, Iliyan, Jahanshad, Neda, Jia, Tianye, Kelly, Sinead, Klein, Marieke, Kwon, Jun Soo, Laansma, Max A, Leerssen, Jeanne, Lueken, Ulrike, Marie Bas-Hoogendam, Janna, Neill, Joseph O', Nunes, Abraham, Opel, Nils, Piras, Fabrizio, Piras, Federica, Postema, Merel C, Pozzi, Elena, Salminen, Lauren E, Shatokhina, Natalia, Soriano-Mas, Carles, Spalletta, Gianfranco, Sun, Daqiang, Teumer, Alexander, Thomopoulos, Sophia I, Thompson, Paul M, Tilot, Amanda K, Tozzi, Leonardo, van der Merwe, Celia, Van Someren, Eus JW, van Wingen, Guido A, Völzke, Henry, Walton, Esther, Wang, Lei, Winkler, Anderson M, Wittfeld, Katharina, Wright, Margaret J, Yun, Je-Yeon, Zhang, Guohao, Zhang-James, Yanli   +99 more
core  

Recovery From Anorexia Nervosa: A Concept Analysis

Journal of Advanced Nursing, Volume 82, Issue 5, Page 4840-4875, May 2026.
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley   +1 more source

Endophenotypes: multiplicity of variants and possible interpretations

Современная зарубежная психология, 2012
The concept of endophenotype comprises hereditary characteristics of human body and psyche, correlating with behavioral (psychological) displays of normal functioning and mental disorders.
Maryutina T.M.
doaj  

Towards Mechanism‐Informed Treatments for Mental Health

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuropsychiatric disorders impose a major global health burden, and current treatments, which historically mostly targeted dopamine and serotonin dysfunctions, often provide only partial, symptomatic relief. This review highlights emerging evidence that additional neuromodulator systems, including acetylcholine, norepinephrine, and endocannabinoids ...
Iker Bengoetxea de Tena, Farhanah Nabilah Sallie, Arvie Rodriguez Abiero, Beatrice Rizzi, Leandro Gabriel Champarini, Elisa Corti, Gianluca Masella, Ariel L. Dunn, Luisa Bandeira Binder, Tyler J. Wenzel, Agustin I. Robles, Roberta G. Anversa, Cécilia Tremblay, Aliance Romain Fokoua, Randriely Merscher Sobreira de Lima, Mateus D'Ávila, Trang T. T. Truong, Jessica C. Pierce, Rui S. Rodrigues, Luis Dinamarca‐Villarroel, Felipe Borges Almeida, Aino‐Kaisa Piironen, Andrey F. L. Aguiar, Andrés M. Jaramillo, Lucas Santos, Anja de Lange, David J. Nutt, Andrew J. Lawrence   +27 more
wiley   +1 more source

Latent State–Trait and Latent Growth Curve Modeling of Smooth Pursuit Eye Movements

Psychophysiology, Volume 63, Issue 5, May 2026.
ABSTRACT Smooth pursuit eye movement (SPEM) performance has previously been shown to have good reliability. While quantifying the relative amounts of reliable trait and state influences on SPEM is relevant to different lines of research including individual differences, clinical and experimental research, this has not yet been done.
Celina Kullmann, Ulrich Ettinger, Kaja Faßbender   +2 more
wiley   +1 more source