Results 141 to 150 of about 194,866 (319)

Endoplasmic reticulum stress, autophagy, neuroinflammation, and sigma 1 receptors as contributors to depression and its treatment

open access: yesNeural Regeneration Research
The etiological factors contributing to depression and other neuropsychiatric disorders are largely undefined. Endoplasmic reticulum stress pathways and autophagy are well-defined mechanisms that play critical functions in recognizing and resolving ...
Chika Fujii   +2 more
doaj   +1 more source

Multiplex stimulated Raman scattering imaging cytometry reveals cancer metabolic signatures in a spatially, temporally, and spectrally resolved manner [PDF]

open access: yesarXiv, 2019
In situ measurement of cellular metabolites is still a challenge in biology. Conventional methods, such as mass spectrometry or fluorescence microscopy, would either destruct the sample or introduce strong perturbations to the functions of target molecules.
arxiv  

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

open access: yesAdvanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

open access: yesAdvanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng   +8 more
wiley   +1 more source

TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells

open access: yesCell Death Discovery
The release of Ca2+ ions from endoplasmic reticulum calcium stores is a key event in a variety of cellular processes, including gene transcription, migration and proliferation.
Alice H. L. Bong   +7 more
doaj   +1 more source

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

open access: yesAdvanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao   +11 more
wiley   +1 more source

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