Results 21 to 30 of about 207,246 (261)

RBM10 Regulates Embryonic Trophoblast Injury via Endoplasmic Reticulum Stress

open access: yesClinical and Experimental Obstetrics & Gynecology, 2022
Background: Previous studies shown that RNA binding motif proteins (RBM) participate in regulating various physiological processes such as cell autophagy, proliferation, and apoptosis, and are abnormally highly expressed in placental trophoblast cells ...
Xiao Chen   +4 more
doaj   +1 more source

Mechanism of Endoplasmic Reticulum Stress Pathway in the Osteogenic Phenotypic Transformation of Aortic Valve Interstitial Cells

open access: yesFrontiers in Endocrinology, 2022
Background and PurposeCalcific Aortic Valve Disease (CAVD) is a crucial component of degenerative valvular disease in old age and with the increasing prevalence of the aging population.
Yiming Tao   +13 more
doaj   +1 more source

Obesity and endoplasmic reticulum (ER) stresses [PDF]

open access: yesFrontiers in Immunology, 2012
In obesity, the adipose cells behave as inflammatory source and result to low grade inflammation. This systemic inflammation along with oxidative stress is a silent killer and damages other vital organs also. High metabolic process, induced due to high nutritional intake, results to endoplasmic reticulum (ER) stress and mitochondrial stress.
Tripathi, Yamini B., Pandey, Vivek
openaire   +3 more sources

Endoplasmic Reticulum Stress in the Heart [PDF]

open access: yesCirculation Research, 2007
Over the last decade, it has become clear that the accumulation of misfolded proteins contributes to a number of neurodegenerative, immune, and endocrine pathologies, as well as other age-related illnesses. Recent interest has focused on the possibility that the accumulation of misfolded proteins can also contribute to vascular and cardiac diseases. In
openaire   +2 more sources

Research progress of endoplasmic reticulum stress of hypoxic pulmonary hypertension [PDF]

open access: yesJichu yixue yu linchuang, 2023
Hypoxic pulmonary hypertension (HPH) is a serious complication caused by long-term hypoxia,which is characterized by persistent vasoconstriction and irreversible vascular remodeling.
LIU Xingxing, WANG Weiwei, YUAN Haoxin
doaj   +1 more source

Endoplasmic Reticulum Stress and Metallothionein

open access: yesChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Masao, Sato, Shinya, Suzuki
openaire   +3 more sources

Endoplasmic Reticulum Stress in Bone Metastases [PDF]

open access: yesFrontiers in Oncology, 2020
Metastases-the spreading of cancer cells from primary tumors to distant organs, including bone-is often incurable and is the major cause of morbidity in cancer patients. Understanding how cancer cells acquire the ability to colonize to bone and become overt metastases is critical to identify new therapeutic targets and develop new therapies against ...
Longyong Xu   +11 more
openaire   +3 more sources

Membrane-associated RING ubiquitin ligase RNF-121 and advancement of cancer [PDF]

open access: yesCellular, Molecular and Biomedical Reports
Exploration of E3 ubiquitin ligases as potential therapeutic targets has been ongoing for two to three decades. Various chemicals and drugs have been developed to either upregulate or inhibit the activity of E3 ligases, aiming to mitigate several ...
Somesh Roy
doaj   +1 more source

Endoplasmic reticulum stress and atherosclerosis [PDF]

open access: yesNature Medicine, 2010
Atherosclerosis and related cardiovascular diseases represent one of the greatest threats to human health worldwide. Despite important progress in prevention and treatment, these conditions still account for one third of all deaths annually. Often presented together with obesity, insulin resistance and type 2 diabetes, these chronic diseases are ...
openaire   +2 more sources

Endoplasmic reticulum stress and organoids [PDF]

open access: yesOrganoid, 2021
Organoids represent an advanced tool in cell biology and have redefined biomedical research. Organoids are ideal for studies of biological processes, pharmacological studies, and therapeutic research to imitate pathological processes and preserve genetic
Rashedul Alam   +3 more
doaj   +1 more source

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