Results 41 to 50 of about 2,960,809 (306)
Destroy and exploit: catalyzed removal of hydroperoxides from the endoplasmic reticulum [PDF]
, 2013 Peroxidases are enzymes that reduce hydroperoxide substrates. In many cases, hydroperoxide reduction is coupled to the formation of a disulfide bond, which is transferred onto specific acceptor molecules, the so-called reducing substrates.
Thomas Ramming +3 more
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GRP78 as a Target for Prevention of Age-Related Cataract by Regulation of Reticulum
, 2023 Cataract is the most common causes of blindness worldwide. The most common kind of cataract is age-related cataract. Measures to prevent the development of cataracts are urgently needed.
Endoplasmic Stress,
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Endoplasmic reticulum stress in pulmonary fibrosis [PDF]
Matrix Biology, 2018 Endoplasmic reticulum (ER) stress is associated with development and progression of fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). ER stress was first implicated in the pathogenesis of IPF >15 years ago with the discovery of disease-causing mutations in surfactant protein C, which result in a misfolded gene product in type II ...
Ankita, Burman +2 more
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Endoplasmic Reticulum Stress and Diabetic Cardiomyopathy [PDF]
Experimental Diabetes Research, 2012 The endoplasmic reticulum (ER) is an organelle entrusted with lipid synthesis, calcium homeostasis, protein folding, and maturation. Perturbation of ER-associated functions results in an evolutionarily conserved cell stress response, the unfolded protein response (UPR) that is also called ER stress.
Jiancheng Xu, Qi Zhou, Wei Xu, Lu Cai
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Endoplasmic reticulum H₂O₂ : Ero1-driven generation and GPx-mediated detoxification [PDF]
, 2014 Endoplasmic reticulum (ER) oxidoreductin 1 alpha (Ero1alpha) is an ER-resident oxidase, which utilizes molecular oxygen (O2) as terminal electron acceptor to produce disulfide bonds and hydrogen peroxide (H2O2).
Ramming, Thomas
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Endoplasmic Reticulum Stress and Metallothionein
ChemInform, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Masao, Sato, Shinya, Suzuki
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Neural Regeneration Research, 2015 Cerebral ischemia triggers secondary ischemia/reperfusion injury and endoplasmic reticulum stress initiates cell apoptosis. However, the regulatory mechanism of the signaling pathway remains unclear.
Jian-wen Yang, Zhi-ping Hu
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Ferroptosis and endoplasmic reticulum stress in ischemic stroke
Neural Regeneration ResearchFerroptosis is a form of non-apoptotic programmed cell death, and its mechanisms mainly involve the accumulation of lipid peroxides, imbalance in the amino acid antioxidant system, and disordered iron metabolism.
Yina Li +6 more
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BMC Musculoskeletal Disorders, 2023 Background We aimed to establish an osteosarcoma prognosis prediction model based on a signature of endoplasmic reticulum stress-related genes. Methods Differentially expressed genes (DEGs) between osteosarcoma with and without metastasis from The Cancer
Yong Zhao +5 more
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The physiological functions of mammalian endoplasmic oxidoreductin 1: on disulfides and more [PDF]
, 2012 Significance: The oxidative process of disulfide-bond formation is essential for the folding of most secretory and membrane proteins in the endoplasmic reticulum (ER).
Ramming, Thomas +1 more
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