Results 51 to 60 of about 462,885 (376)
The Roles of the Ubiquitin–Proteasome System in the Endoplasmic Reticulum Stress Pathway
International Journal of Molecular Sciences, 2021 The endoplasmic reticulum (ER) is a highly dynamic organelle in eukaryotic cells, which is essential for synthesis, processing, sorting of protein and lipid metabolism.
Junyan Qu, Tingting Zou, Zhenghong Lin
semanticscholar +1 more source
Endoplasmic Reticulum Stress and Metallothionein
ChemInform, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Shinya Suzuki, Masao Sato
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Endoplasmic Reticulum Stress in Endometrial Cancer [PDF]
Frontiers in Medicine, 2014 Endometrial cancer (EC) is a common gynecologic malignancy often diagnosed at early stage. In spite of a huge advance in our understanding of EC biology, therapeutic modalities do not have significantly changed over the past 40 years. A restricted number of genes have been reported to be mutated in EC, mediating cell proliferation and invasiveness ...
Ulianich L, Insabato L
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Endoplasmic Reticulum Stress in Bone Metastases [PDF]
Frontiers in Oncology, 2020 Metastases-the spreading of cancer cells from primary tumors to distant organs, including bone-is often incurable and is the major cause of morbidity in cancer patients. Understanding how cancer cells acquire the ability to colonize to bone and become overt metastases is critical to identify new therapeutic targets and develop new therapies against ...
Longyong Xu +11 more
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The endoplasmic reticulum in plant immunity and cell death [PDF]
, 2012 The endoplasmic reticulum (ER) is a highly dynamic organelle in eukaryotic cells and a major production site of proteins destined for vacuoles, the plasma membrane, or apoplast in plants.
Eichmann, Ruth, Schäfer, P. (Patrick)
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Endoplasmic Reticulum Stress in Metabolic Disorders [PDF]
Cells, 2018 Metabolic disorders have become among the most serious threats to human health, leading to severe chronic diseases such as obesity, type 2 diabetes, non-alcoholic fatty liver disease, as well as cardiovascular diseases. Interestingly, despite the fact that each of these maladies has different physiological and clinical symptoms, they appear to share ...
Rose Ghemrawi +2 more
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Mechanism of Endoplasmic Reticulum Stress in Cerebral Ischemia
Frontiers in Cellular Neuroscience, 2021 Endoplasmic reticulum (ER) is the main organelle for protein synthesis, trafficking and maintaining intracellular Ca2+ homeostasis. The stress response of ER results from the disruption of ER homeostasis in neurological disorders.
Yu Han +5 more
semanticscholar +1 more source
Oncology Report, 2021 External and internal stimuli are often involved in the pathogenesis of tumors, and the deterioration of endoplasmic reticulum (ER) function within cells is also an important etiological factor of tumorigenesis resulting in the impairment of the ...
Xiaojing Fu +6 more
semanticscholar +1 more source
Endoplasmic reticulum and Golgi stress in microcephaly [PDF]
Cell Stress, 2019 Microcephaly is a neurodevelopmental condition characterized by a small brain size associated with intellectual deficiency in most cases and is one of the most frequent clinical sign encountered in neurodevelopmental disorders. It can result from a wide range of environmental insults occurring during pregnancy or postnatally, as well as from various ...
Passemard, Sandrine +3 more
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Frontiers in Physiology, 2023 Introduction: Bronchopulmonary dysplasia (BPD) is a life-threatening lung illness that affects premature infants and has a high incidence and mortality.
Ziyu Tao +9 more
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