Results 261 to 270 of about 47,261 (313)

Delivery of Antisense Oligonucleotides Using the Nano‐Cell Vesicle Technology System (nCVTs) for Targeted Cancer Therapy

Small, Volume 22, Issue 8, 6 February 2026.
Nano‐Cell Vesicle Technology (nCVTs) integrates cationic lipids with tumor‐homing cell membranes to achieve efficient intracellular transport of antisense oligonucleotides. The system enhances nuclear delivery, minimizes cytotoxicity, and suppresses tumor growth in vivo, establishing nCVTs as a versatile and biocompatible platform for next‐generation ...
Yi Hsuan Ou, Wei Heng Chng, Ram Pravin Kumar Muthuramalingam, Prathyusha Raghunathan, Nichakan Khunkitchai, Choon Keong Lee, Jae Ha Jun, Zi Xiu Ng, Phua Tian Xin, Wei Jiang Goh, Jiong‐Wei Wang, Bertrand Czarny   +11 more
wiley   +1 more source

Endosomal escape and current obstacles in ionizable lipid nanoparticles mediated gene delivery: lessons from COVID-19 vaccines

Semmal Syed Meerasa, Aqeel Ahmad, A. A. Khan, Shafiul Haque, Imran Saleem   +4 more
openalex   +1 more source

Biomechanics and Thermodynamics of Nanoparticle Interactions with Plasma and Endosomal Membrane Lipids in Cellular Uptake and Endosomal Escape

, 2014
Chiranjeevi Peetla, Shi-hua Jin, Jonathan Weimer, Adekunle Elegbede, Vinod Labhasetwar   +4 more
openalex   +2 more sources

Nanobiotechnology‐Based Approaches for Uveal Melanoma Treatment

SmartMat, Volume 7, Issue 1, February 2026.
Emerging platforms for uveal melanoma combine precision drug delivery, ROS‐amplifying modalities, and nucleic acid transport to overcome ocular barriers and immunosuppressive niches. Targeted nanoparticles, virus‐like constructs, and injectable depots enable localized activation, controlled release, and gene‐level reprogramming.
Nadezhda A. Pechnikova, Ioannis Iliadis, Malamati Poimenidou, Chrysi Patsidou, Maria Zafeiriou‐Chatziefraimidou, Diamantis D. Almaliotis, Ioannis T. Tsinopoulos, Ivan V. Zelepukin, Alexey V. Yaremenko   +8 more
wiley   +1 more source

siRNA-loaded poly(histidine-arginine)₆-modified chitosan nanoparticle with enhanced cell-penetrating and endosomal escape capacities for suppressing breast tumor metastasis

, 2017
Ping Sun, Wei Huang, Lin Kang, Mingji Jin, Bo Fan, Hongyan Jin, Qiming Wang, Zhonggao Gao   +7 more
openalex   +2 more sources

Advances in the Development of Lipid Nanoparticles for mRNA Delivery

Small Structures, Volume 7, Issue 2, February 2026.
This review provides an integrated overview of mRNA–lipid nanoparticle (LNP) design, including lipid composition, scalable manufacturing, and structure–activity relationships. We highlight strategies for targeted delivery, physicochemical tuning, and high‐throughput screening such as DNA barcoding.
Xing Wang, Letao Xu, Zhenwei Lan, Yue Hui, Yun Liu, Guangze Yang, Chun‐Xia Zhao   +6 more
wiley   +1 more source

Logic‐Embedded Vectors for Intracellular Partitioning, Endosomal Escape, and Exocytosis of Nanoparticles

, 2010
Rita E. Serda, Aaron Mack, Anne L. van de Ven, Silvia Ferrati, Kenneth Dunner, Biana Godin, Ciro Chiappini, Matthew Landry, Louis Brousseau, Xuewu Liu, Andrew J. Bean, Mauro Ferrari   +11 more
openalex   +2 more sources

Bacterial Expression of Gene‐Encoding DNA Origami Structures

Small Structures, Volume 7, Issue 2, February 2026.
Bacterial targeting via programmable DNA origami, varying in rigidity and compactness is unexplored. In transformation assays, origami reduces transformation efficiency compared to single‐stranded scaffolds. Structural features and surface modifications, however, improve transformation outcomes.
Verena Dobretzberger, Alexander Hebel, Maria Ponetsmüller, Florian Ohner, Trishant R. Umrekar, Morgan Beeby, Friedrich C. Simmel, Ivan Barišić   +7 more
wiley   +1 more source

Swelling, Rupture and Endosomal Escape of Biological Nanoparticles Per Se and Those Fused with Liposomes in Acidic Environment. [PDF]

Pharmaceutics
Ponomareva N, Brezgin S, Karandashov I, Kostyusheva A, Demina P, Slatinskaya O, Bayurova E, Silachev D, Pokrovsky VS, Gegechkori V, Khaydukov E, Maksimov G, Frolova A, Gordeychuk I, Zamyatnin AA, Chulanov V, Parodi A, Kostyushev D.   +17 more
europepmc   +1 more source

Controlling Endosomal Escape Using pH-Responsive Nanoparticles with Tunable Disassembly

, 2018
Nachnicha Kongkatigumjorn, Samuel A. Smith, Moore Chen, Katie Fang, Shenglin Yang, Elizabeth R. Gillies, Angus P. R. Johnston, Georgina K. Such   +7 more
openalex   +2 more sources