Results 11 to 20 of about 10,879 (101)
Early endosomes and endosomal coatomer are required for autophagy [PDF]
, 2009 Autophagy, an intracellular degradative pathway, maintains cell homeostasis under normal and stress conditions. Nascent double-membrane autophagosomes sequester and enclose cytosolic components and organelles, and subsequently fuse with the endosomal ...
Tooze, Sharon A. +2 more
core +3 more sources
eLife, 2021 In eukaryotic cells, intracellular components are organized by the microtubule motors cytoplasmic dynein-1 (dynein) and kinesins, which are linked to cargos via adaptor proteins.
Jenna R Christensen +6 more
doaj +1 more source
Endosome-dependent trafficking and secretion of ApoE.
, 2023 (A-C) Microtubule-dependent motility of intracellular ApoE-CD63 double-positive structures. (A) Mean squared displacement (MSD) of general ApoE and CD63 trafficking in mock and colchicine-treated cells.
Karl Rohr (41937) +9 more
core +1 more source
p120 catenin recruits HPV to γ-secretase to promote virus infection.
PLoS Pathogens, 2020 During internalization and trafficking, human papillomavirus (HPV) moves from the cell surface to the endosome where the transmembrane protease γ-secretase promotes insertion of the viral L2 capsid protein into the endosome membrane.
Mara Calypso Harwood +4 more
doaj +1 more source
Rabaptin5 is recruited to endosomes by Rab4a and Rabex5 to regulate endosome maturation [PDF]
, 2014 Membrane trafficking between organelles is fundamental to the existence of eukaryotic cells. A multitude of proteins is involved in membrane trafficking, acting as building blocks for transport carriers, regulators of transport, and targeting and fusion ...
Kälin, Simone
core +1 more source
A 115 kDa calmodulin-binding protein is located in rat liver endosome fractions [PDF]
, 1988 The distribution of calmodulin-binding polypeptides in various rat liver subcellular fractions was investigated. Plasma-membrane, endosome, Golgi and lysosome fractions were prepared by established procedures.
Enrich, C. +2 more
core +4 more sources
Open Biology, 2021 The membranes of endosomes, phagosomes and macropinosomes can become damaged by the physical properties of internalized cargo, by active pathogenic invasion or by cellular processes, including endocytic maturation.
Eleanor Childs +3 more
doaj +1 more source
Novel Factors at Endoplasmic Reticulum-Endosome Contact Sites [PDF]
, 2018 The endoplasmic reticulum is the cell’s platform for protein and lipid synthesis. Not only does the ER perform these functions, but it also regulates other organelles through membrane contact sites.
Hoyer, Melissa J.
core +2 more sources
Frontiers in Cell and Developmental Biology, 2020 DDHD1 and DDHD2 are both intracellular phospholipases A1 and hydrolyze phosphatidic acid in vitro. Given that phosphatidic acid participates in neurite outgrowth, we examined whether DDHD1 and DDHD2 regulate neurite outgrowth.
Yuki Maemoto +8 more
doaj +1 more source
Cell Reports, 2014 Summary: Endosome-to-Golgi retrieval is an essential membrane trafficking pathway required for many important physiological processes and linked to neurodegenerative disease and infection by bacterial and viral pathogens.
Sophia Y. Breusegem +1 more
doaj +1 more source