Results 41 to 50 of about 10,879 (101)
CellsIntracellular cargo delivery via distinct transport routes relies on vesicle carriers. A key trafficking route distributes cargo taken up by clathrin-mediated endocytosis (CME) via early endosomes.
Hafiza Nosheen Saleem +5 more
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Frontiers in Immunology, 2018 Dendritic cell (DC) expression of CD103, the α subunit of αEβ7 integrin, is thought to enable DC interactions with E-cadherin-expressing gastrointestinal epithelia for improved mucosal immunosurveillance.
Steve Swain +8 more
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SARS‐CoV‐2 spike protein harnesses SNX27‐mediated endocytic recycling pathway
MedComm, 2021 SARS‐CoV‐2 is an enveloped positive‐sense RNA virus that depends on host factors for all stages of its life. Membrane receptor ACE2 is a well‐established factor for SARS‐CoV‐2 docking.
Lin Zhao +5 more
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Septins as modulators of endo-lysosomal membrane traffic
Frontiers in Cell and Developmental Biology, 2016 Septins constitute a family of GTP-binding proteins, which assemble into non-polar filaments in a nucleotide-dependent manner. These filaments can be recruited to negatively charged membrane surfaces.
Kyungyeun Song +2 more
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Cancer Biology & Medicine, 2020 Objectives: Improper activation of Wnt/β-catenin signaling has been implicated in human diseases. Beyond the well-studied glycogen synthase kinase 3β (GSK3β) and casein kinase 1 (CK1), other kinases affecting Wnt/β-catenin signaling remain to be defined.
Danmin Ou +10 more
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Hepatic endosome fractions contain an ATP-driven proton pump
, 1985 Endosome fractions were isolated from rat liver homogenates on the basis of the subcellular distribution of circulating ligands, e.g. 125I-asialotransferrin internalized by hepatocytes by a receptor-mediated process.
Flint, N. +2 more
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The Curious Case of Arenavirus Entry, and Its Inhibition
Viruses, 2012 Arenaviruses comprise a diverse family of enveloped negative-strand RNA viruses that are endemic to specific rodent hosts worldwide. Several arenaviruses cause severe hemorrhagic fevers in humans, including Junín and Machupo viruses in South America and ...
Joanne York, Jack H. Nunberg
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A new Rab7 effector controls phosphoinositide conversion in endosome maturation
, 2017 Endosome maturation requires a coordinated change in the Rab GTPase and phosphoinositide composition of the endosomal membrane. In this issue, Liu et al. (2017. J. Cell Biol.
Bettina Winckler, James E. Casanova
core +1 more source
Frontiers in Cellular Neuroscience, 2016 AGAP1 is an Arf1 GTPase activating protein that interacts with the vesicle-associated protein complexes adaptor protein 3 (AP-3) and Biogenesis of Lysosome Related Organelles Complex-1 (BLOC-1). Overexpression of AGAP1 in non-neuronal cells results in an
Miranda Arnold +11 more
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Frontiers in Cellular and Infection Microbiology, 2017 Edwardsiella tarda is a Gram-negative bacterium that can infect a broad range of hosts including humans and fish. Accumulating evidences have indicated that E. tarda is able to survive and replicate in host phagocytes.
Zhi-hai Sui +10 more
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