Results 41 to 50 of about 138,036 (346)

Rab11-FIP3 is a cell cycle-regulated phosphoprotein [PDF]

, 2012
<b>BACKGROUND:</b> Rab11 and its effector molecule, Rab11-FIP3 (FIP3), associate with recycling endosomes and traffic into the furrow and midbody of cells during cytokinesis.
Xinzi Yu, Simon, G, Glenn Simon, Prekeris, R., Simon, G., Matheson Johanne, Miller, MC, Collins, L.L., Miller, M Clare, Otani Tetsuhisa, Rytis Prekeris, M Clare Miller, Hayashi, S, Yu Xinzi, Prekeris Rytis, Yu, X, Otani, Tetsuhisa, Gould, Gwyn W, Matheson, J., Prekeris, R, Shigeo Hayashi, Gould, GW, Louise L Collins, Miller, M.C., Wu, C., Collins, LL, Christine Wu, Hayashi, Shigeo, Collins Louise L, Hayashi Shigeo, Simon, Glenn, Yu, Xinzi, Miller M Clare, Simon Glenn, Otani, T, Matheson, Johanne, Yu, X., Gould, G.W., Wu, Christine, Collins, Louise L, Gwyn W Gould, Tetsuhisa Otani, Wu, C, Johanne Matheson, Otani, T., Hayashi, S., Prekeris, Rytis, Wu Christine, Matheson, J, Gould Gwyn W   +49 more
core   +1 more source

Life in the lumen: The multivesicular endosome

Traffic : the International Journal of Intracellular Transport, 2019
The late endosomes/endo‐lysosomes of vertebrates contain an atypical phospholipid, lysobisphosphatidic acid (LBPA) (also termed bis[monoacylglycero]phosphate [BMP]), which is not detected elsewhere in the cell.
J. Gruenberg
semanticscholar   +1 more source

SNX-BAR-mediated endosome tubulation is coordinated with endosome maturation [PDF]

, 2012
Endosomal sorting is essential for cell homeostasis. Proteins targeted for degradation are retained in the maturing endosome vacuole while others are recycled to the cell surface or sorted to the biosynthetic pathway via tubular transport carriers ...
Verkade, P, Cullen, PJ, Cullen, Peter J., van Weering, Jan R.T., Verkade, Paul, van Weering, JRT   +5 more
core   +1 more source

Effects of Excess Brain-Derived Human α-Synuclein on Synaptic Vesicle Trafficking

Frontiers in Neuroscience, 2021
α-Synuclein is a presynaptic protein that regulates synaptic vesicle trafficking under physiological conditions. However, in several neurodegenerative diseases, including Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, α ...
Cristina Román-Vendrell, Audrey T. Medeiros, John B. Sanderson, Haiyang Jiang, Tim Bartels, Jennifer R. Morgan   +5 more
doaj   +1 more source

Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability

ACS Nano, 2019
Endolysosome entrapment is one of the key barriers to the therapeutic use of biologic drugs that act intracellularly. The screening of prospective nanoscale endosome-disrupting delivery technologies is currently limited by methods that are indirect and ...
Kameron V. Kilchrist, Somtochukwu C. Dimobi, Meredith A. Jackson, Brian C Evans, T. Werfel, E. Dailing, Sean K Bedingfield, Isom B. Kelly, C. Duvall   +8 more
semanticscholar   +1 more source

Live imaging of endosome dynamics [PDF]

, 2014
When studying the living endosome one must first recognise that we are not studying a single discrete organelle but rather a highly dynamic interconnected network of membrane-bound compartments.
Teasdale, Rohan D., Rohan D. Teasdale, Kerr, Markus, Markus Kerr   +3 more
core   +1 more source

Astrocytes Are a Key Target for Neurotropic Viral Infection

Cells, 2023
Astrocytes are increasingly recognized as important viral host cells in the central nervous system. These cells can produce relatively high quantities of new virions.
Maja Potokar, Robert Zorec, Jernej Jorgačevski   +2 more
doaj   +1 more source

Cytoplasmic dynein and early endosome transport [PDF]

, 2015
Microtubule-based distribution of organelles/vesicles is crucial for the function of many types of eukaryotic cells and the molecular motor cytoplasmic dynein is required for transporting a variety of cellular cargos toward the microtubule minus ends ...
Xiang, X, Yao, X, Qiu, R, Arst, HN, Pealva, MA, Zhang, J   +5 more
core   +1 more source

Structure of cellular ESCRT-III spirals and their relationship to HIV budding

eLife, 2014
The ESCRT machinery along with the AAA+ ATPase Vps4 drive membrane scission for trafficking into multivesicular bodies in the endocytic pathway and for the topologically related processes of viral budding and cytokinesis, but how they accomplish this ...
Anil G Cashikar, Soomin Shim, Robyn Roth, Michael R Maldazys, John E Heuser, Phyllis I Hanson   +5 more
doaj   +1 more source

Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors

Journal of Cell Science, 2019
Recycling endosomes are stations that sort endocytic cargoes to their appropriate destinations. Tubular endosomes have been characterized as a recycling endosomal compartment for clathrin-independent cargoes.
Kan Etoh, M. Fukuda
semanticscholar   +1 more source