Results 51 to 60 of about 10,879 (101)

Synaptic Vesicle Recycling and the Endolysosomal System: A Reappraisal of Form and Function

Frontiers in Synaptic Neuroscience, 2022
The endolysosomal system is present in all cell types. Within these cells, it performs a series of essential roles, such as trafficking and sorting of membrane cargo, intracellular signaling, control of metabolism and degradation.
Daniela Ivanova, Daniela Ivanova, Daniela Ivanova, Michael A. Cousin, Michael A. Cousin, Michael A. Cousin   +5 more
doaj   +1 more source

Recycling endosome membrane incorporation into the leading edge regulates lamellipodia formation and macrophage migration

, 2010
In comparison to our knowledge of the recycling of adhesion receptors and actin assembly, exactly how the cell controls its surface membrane to form a lamellipodium during migration is poorly understood.
Murray, Rachael, Kelly J. Veale, Ruby P. Estrella, Whittaker, Shane P., Murray, Rachael Z., Veale, Kelly, Veale, Kelly J., Carolin Offenhäuser, Estrella, Ruby P., Shane P. Whittaker, Offenhäuser, Carolin, Whittaker, Shane, Estrella, Ruby, Rachael Z. Murray   +13 more
core   +1 more source

Post-Golgi Trafficking and Transport of Cell Wall Components

Frontiers in Plant Science, 2018
The cell wall, a complex macromolecular composite structure surrounding and protecting plant cells, is essential for development, signal transduction, and disease resistance. This structure is also integral to cell expansion, as its tensile resistance is
Rosalie Sinclair, Michel Ruiz Rosquete, Georgia Drakakaki   +2 more
doaj   +1 more source

Mechanisms by which SNX-BAR subfamily controls the fate of SNXs’ cargo

Frontiers in Physiology
The SNX-BAR subfamily is a component of the sorting nexins (SNXs) superfamily. Distinct from other SNXs, which feature a PX domain for phosphoinositide binding, the SNX-BAR subfamily includes a BAR domain that induces membrane curvature.
Yaolin Long, Yang Li, Jin Xue, Wanqing Geng, Mingxia Ma, Xiaohui Wang, Li Wang   +6 more
doaj   +1 more source

Endosome–lysosome fusion

, 2010
The delivery of endocytosed cargo to lysosomes occurs through kissing and direct fusion of late endosomes/MVBs (multivesicular bodies) and lysosomes. Live-cell and electron microscopy experiments together with cell-free assays have allowed us to describe
J. Paul Luzio, Nicholas A. Bright, Sally R. Gray   +2 more
core   +1 more source

Transport mechanisms between the endocytic, recycling, and biosynthetic pathways via endosomes and the trans-Golgi network

Frontiers in Cell and Developmental Biology
After the endocytic and biosynthetic pathway converge, they partially share the route to the lysosome/vacuole. Similarly, the endocytic recycling and secretory pathways also partially share the route to the plasma membrane.
Junko Y. Toshima, Jiro Toshima
doaj   +1 more source

Visualization of Ras-PI3K interaction in the endosome using BiFC [PDF]

, 2009
Recent studies indicate the importance of spatiotemporal regulation in the diversity and specificity of intracellular signaling. Here, we show that Ras-PI3K signaling plays an important role in the local regulation of phosphatidylinositol metabolism in ...
Ohba, Yusuke, Tsuda, Masumi, Tsutsumi, Kaori, Kawaguchi, Hideaki, Fujioka, Yoichiro   +4 more
core   +1 more source

ALG-2-interacting Tubby-like protein superfamily member PLSCR3 is secreted by an exosomal pathway and taken up by recipient cultured cells

Bioscience Reports, 2013
PLSCRs (phospholipid scramblases) are palmitoylated membrane-associating proteins. Regardless of the given names, their physiological functions are not clear and thought to be unrelated to phospholipid scrambling activities observed in vitro ...
Tatsutoshi Inuzuka, Akira Inokawa, Cen Chen, Kumiko Kizu, Hiroshi Narita, Hideki Shibata, Masatoshi Maki   +6 more
doaj   +1 more source

Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids [PDF]

, 2013
Very long-chain fatty acids (VLCFAs), fatty acids with chain length of > 20, possess a wide range of biological functions. However, their roles at the molecular level remain largely unknown.
Obara, Keisuke, Kihara, Akio, Kojima, Ryo   +2 more
core   +1 more source

Distribution and Co-localization of endosome markers in cells

Heliyon, 2019
Clathrin mediated endocytosis is one pathway for internalization of extracellular nano materials into cells [1, 2]. In this pathway, proteins attached to receptors and the internalized materials are encapsulated in clathrin coated membrane vesicles that ...
Lindsay J. Shearer, Nils O. Petersen
doaj   +1 more source