Results 31 to 40 of about 138,036 (346)
Endosome-to-TGN Trafficking: Organelle-Vesicle and Organelle-Organelle Interactions
Frontiers in Cell and Developmental Biology, 2020 Retrograde transport from endosomes to the trans-Golgi network (TGN) diverts proteins and lipids away from lysosomal degradation. It is essential for maintaining cellular homeostasis and signaling. In recent years, significant advancements have been made
Yingfeng Tu +3 more
semanticscholar +1 more source
Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes [PDF]
The Journal of cell biology, 1992 After endocytosis, lysosomally targeted ligands pass through a series of endosomal compartments. The endocytic apparatus that accomplishes this passage may be considered to take one of two forms: (a) a system in which lysosomally targeted ligands pass through preexisting, long-lived early sorting endosomes and are then selectively transported to long ...
K W, Dunn, F R, Maxfield
openaire +3 more sources
Open Biology, 2021 The membranes of endosomes, phagosomes and macropinosomes can become damaged by the physical properties of internalized cargo, by active pathogenic invasion or by cellular processes, including endocytic maturation.
Eleanor Childs +3 more
doaj +1 more source
An ESCRT into the Endosome [PDF]
Molecular Cell, 2002 Multivesicular endosomes sort ubiquitinated membrane proteins for degradation by incorporating them into inwardly budding vesicles. The recent identification of two new oligomeric components of the sorting machinery gives us a detailed view of the complex protein-protein interactions driving this process.
openaire +2 more sources
Vaccinia Virus Infection Requires Maturation of Macropinosomes. [PDF]
, 2015 The prototypic poxvirus, vaccinia virus (VACV), occurs in two infectious forms, mature virions (MVs) and extracellular virions (EVs). Both enter HeLa cells by inducing macropinocytic uptake.
Mercer, Jason +13 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2020 DDHD1 and DDHD2 are both intracellular phospholipases A1 and hydrolyze phosphatidic acid in vitro. Given that phosphatidic acid participates in neurite outgrowth, we examined whether DDHD1 and DDHD2 regulate neurite outgrowth.
Yuki Maemoto +8 more
doaj +1 more source
The enigmatic endosome – sorting the ins and outs of endocytic trafficking
Journal of Cell Science, 2018 The early endosome (EE), also known as the sorting endosome (SE) is a crucial station for the sorting of cargoes, such as receptors and lipids, through the endocytic pathways.
Naava Naslavsky, S. Caplan
semanticscholar +1 more source
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
, 2007 Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Falguières, Thomas +15 more
core +1 more source
Cell Reports, 2014 Summary: Endosome-to-Golgi retrieval is an essential membrane trafficking pathway required for many important physiological processes and linked to neurodegenerative disease and infection by bacterial and viral pathogens.
Sophia Y. Breusegem +1 more
doaj +1 more source
Current Opinion in Cell Biology, 2015 The endosomal membrane recycling system represents a dynamic conduit for sorting and re-exporting internalized membrane constituents. The recycling system is composed of multiple tubulovesicular recycling pathways that likely confer distinct trafficking pathways for individual cargoes.
openaire +2 more sources