Results 21 to 30 of about 15,277 (204)

Circulatory endostatin level and risk of cardiovascular events in patients with end-stage renal disease on hemodialysis [PDF]

Kidney Research and Clinical Practice
Background Endostatin is released during extracellular matrix remodeling and is involved in the development of vascular pathology and cardiovascular (CV) disease. However, the role of circulating endostatin as a biomarker of vascular calcification and CV
Jin Sug Kim, Miji Kim, Kyung Hwan Jeong, Ju-Young Moon, Sang Ho Lee, Gang Jee Ko, Dong-Young Lee, So Young Lee, Yang Gyun Kim, Hyeon Seok Hwang   +9 more
doaj   +1 more source

Gene Therapy for Pediatric Cancer: State of the Art and Future Perspectives [PDF]

, 2003
While modern treatments have led to a dramatic improvement in survival for pediatric malignancy, toxicities are high and a significant proportion of patients remain resistant.
Biagi, Ettore, Bollard, Catherine, Brenner, Malcolm, Rousseau, Raphael   +3 more
core   +5 more sources

Increased angiogenic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance alters trophoblast function. [PDF]

, 2014
STUDY QUESTION Are the concentrations of factors secreted by decidual natural killer (dNK) cells from pregnancies at high risk of poor spiral artery remodelling different to those secreted from pregnancies at low risk?
A. E. Wallace, A. P. Johnstone, Athanassiades, Cartwright, Choy, Desai, Engert, Fraser, Furuya, G. S. Whitley, Hanna, J. E. Cartwright, Karamouzis, Kim, King, King, Koga, Meekins, Melchiorre, Moroianu, Nasu, Pijnenborg, Pijnenborg, Pollheimer, Prefumo, Prefumo, R. Fraser, Rehn, S. Gurung, S. S. Goulwara, Santoni, Treiber-Held, van der Harten, Verma, Wei, Zhou   +35 more
core   +2 more sources

Antiangiogenesis signals by endostatin [PDF]

The FASEB Journal, 2001
ABSTRACT Endostatin is a potent endogenous angiogenesis inhibitor that induces regression of tumors in mice. Neither an extracellular receptor for endostatin nor intracellular signals that result in the regression of tumor vascular beds have been identified.
M, Shichiri, Y, Hirata
openaire   +2 more sources

Endostatin inhibits VEGF-A induced osteoclastic bone resorption in vitro

BMC Musculoskeletal Disorders, 2006
Background Endostatin is a C-terminal fragment of collagen XVIII which is a component of basement membranes with the structural properties of both collagens and proteoglycans.
Ilvesaro Joanna, Hautala Timo, Nelo Katri, Sipola Annina, Tuukkanen Juha   +4 more
doaj   +1 more source

Endostatin in fibrosis and as a potential candidate of anti-fibrotic therapy

Drug Delivery, 2021
Fibrotic diseases pose significant clinical challenges due to their broadness and complexity. Thus, a better understanding of fibrogenesis and the development of more effective treatments is imperative. Recent evidence suggests a significant antifibrotic
Zequn Zhang, Xi Liu, Zhaolong Shen, Jun Quan, Changwei Lin, Xiaorong Li, Gui Hu   +6 more
doaj   +1 more source

Dual-function injectable angiogenic biomaterial for the repair of brain tissue following stroke. [PDF]

, 2018
Stroke is the primary cause of disability due to the brain's limited ability to regenerate damaged tissue. After stroke, an increased inflammatory and immune response coupled with severely limited angiogenesis and neuronal growth results in a stroke ...
Carmichael, S Thomas, Gojgini, Shiva, Nih, Lina R, Segura, Tatiana   +3 more
core   +1 more source

Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L [PDF]

, 2020
Angiogenesis, tissue invasion and metastasis in the tumour microenvironment are all critical hallmarks of cancer. Upregulation of cathepsin L plays an important role in angiogenesis and metastasis through its ability to degrade the extracellular matrix ...
Pranjol, Md Zahidul I, Tabish, Tanveer A, Whatmore, Jacqueline L, Zhang, Shaowei   +3 more
core   +2 more sources

Combining Bevacizumab with Endostatin Gets Better Antitumor Efficacy in Vivo 
in Lung Cancer Animal Model

Chinese Journal of Lung Cancer, 2013
Background and objective The aim of this study is to investigate difference of antiangiogenesis ablility and interaction about bevacizumab and endostatin in vivo in lung cancer animal model.
Niu NIU, Baolan LI, Chaoyang LIU, Ying HU, Xuebing LI, Jie LI, Heling SHI, Haiqing ZHANG   +7 more
doaj   +1 more source

Serum endostatin levels are associated with diffusion capacity and with tuberous sclerosis- associated lymphangioleiomyomatosis

Orphanet Journal of Rare Diseases, 2019
Endostatin is a naturally occurring collagen fragment with anti-angiogenic properties. We investigated the association between serum endostatin levels and DLCO in a cohort of patients with lymphangioleiomyomatosis (LAM). Associations of endostatin levels
Anthony M. Lamattina, Sergio Poli, Pranav Kidambi, Shefali Bagwe, Andrew Courtwright, Pierce H. Louis, Shikshya Shrestha, Benjamin Stump, Hilary J. Goldberg, Elizabeth A. Thiele, Ivan Rosas, Elizabeth P. Henske, Souheil El-Chemaly   +12 more
doaj   +1 more source