Results 41 to 50 of about 15,277 (204)

Serum Endostatin Levels in Oral Squamous Cell Carcinoma [PDF]

open access: yesIranian Journal of Otorhinolaryngology, 2018
Introduction: Endostatin is a C-­terminal proteolytic fragment of collagen XVIII and, as with angiostatin and thrombospondin, is known as an anti­angiogenic agent.
Maryam Mardani   +5 more
doaj   +1 more source

Intrapleural Administration With Rh-Endostatin and Chemical Irritants in the Control of Malignant Pleural Effusion: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Oncology, 2021
IntroductionA modified and recombinant human endostatin (Rh-endostatin) is often used in the control of malignant pleural effusion (MPE) through intrapleural infusion.ObjectivesTo demonstrate the clinical response, survival, and safety of Rh-endostatin ...
Cheng-Qiong Wang   +18 more
doaj   +1 more source

Validation of an enzyme-linked immunosorbent assay (ELISA) for quantification of endostatin levels in mice as a biomarker of developing glomerulonephritis.

open access: yesPLoS ONE, 2019
Endostatin, the C-terminal fragment of type XVIII collagen, was shown to be one of the most potent endothelial cell-specific inhibitors of angiogenesis.
Jacqueline Wallwitz   +6 more
doaj   +1 more source

Vascular Endothelial Growth FactorC Serum and Endostatin Serum as Predictors of Lympho Vascular Invasion in Early Stage Cervical Cancer

open access: yesIndonesian Journal of Obstetrics and Gynecology, 2017
Objective: To determine the relationship of Vascular Endothelial Growth Factors-C (VEGF-C), endostatin and the ratio of VEGF-C/ endostatin with limfo vascular invasion in patient with early stage cervical cancer.
Andhinna Rusmardiani   +2 more
doaj   +1 more source

Endostatin concentration in plasma of healthy human volunteers [PDF]

open access: yes, 2017
Background: Angiogenesis is involved in many cardiovascular and cancerous diseases, including atherosclerosis and is controlled by a fine balance between angiogenic and angiostatic mediators.
Baxendale, Ronald Hugh   +5 more
core  

Enhanced expression of Vastatin inhibits angiogenesis and prolongs survival in murine orthotopic glioblastoma model [PDF]

open access: yes, 2017
BACKGROUND: Antiangiogenic therapies are considered promising for the treatment of glioblastoma (GB). The non-collagenous C-terminal globular NC1 domain of type VIII collagen a1 chain, Vastatin, is an endogenous antiangiogenic polypeptide.
Hong Yao   +7 more
core   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

open access: yesBMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi   +11 more
wiley   +1 more source

Biomarkers of Extracellular Matrix Remodelling Are Linked to Severity and Outcome of Advanced Chronic Liver Disease

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Extracellular matrix (ECM) remodelling biomarkers reflect portal hypertension and disease severity in advanced chronic liver disease (ACLD). However, their predictive value for disease progression is largely restricted to compensated ACLD (cACLD). ABSTRACT Background Extracellular matrix (ECM) remodelling in advanced chronic liver disease (ACLD) is ...
Benedikt Simbrunner   +17 more
wiley   +1 more source

Retrograde semaphorin-plexin signalling drives homeostatic synaptic plasticity. [PDF]

open access: yes, 2017
Homeostatic signalling systems ensure stable but flexible neural activity and animal behaviour. Presynaptic homeostatic plasticity is a conserved form of neuronal homeostatic signalling that is observed in organisms ranging from Drosophila to human ...
A Mahr   +37 more
core   +1 more source

Endostatin's Antiangiogenic Signaling Network

open access: yesMolecular Cell, 2004
It is here demonstrated that the set of gene expressions underlying the angiogenic balance in tissues can be molecularly reset en masse by a single protein. Using genome-wide expression profiling, coupled with RT-PCR and phosphorylation analysis, we show that the endogenous angiogenesis inhibitor endostatin downregulates many signaling pathways in ...
Abdollahi, Amir   +8 more
openaire   +2 more sources

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