Results 21 to 30 of about 627,382 (283)
Endothelial dysfunction and atherosclerosis [PDF]
European Heart Journal, 1997 Mammalian endothelium acts as a mediator in arterial and venous relaxation and contraction. Endothelium-dependent relaxation is due to endothelial release of powerful, non-prostanoid vasodilatory substances. The best known of these is the endothelial factor EDRF identified as nitrous oxide (NO).
openaire +5 more sources
Drug treatment of hypertension: focus on vascular health [PDF]
, 2016 Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C. +2 more
core +1 more source
Microvascular alterations in hypertension and vascular aging [PDF]
, 2017 Hypertension and aging are characterized by vascular remodelling and stiffness as well as endothelial dysfunction. Endothelial function declines with age, since aging is associated with senescence of the endothelium due to increased rate of apoptosis and
Battistoni, Allegra +5 more
core +1 more source
Exercise training and losartan improve endothelial function in heart failure rats by different mechanisms [PDF]
, 2013 Objectives. To investigate the mechanisms of losartan- and exercise training-induced improvements on endothelial dysfunction in heart failure. Design. Sprague-Dawley rats subjected to left coronary artery ligation inducing myocardial infarction and heart
Crozier I +5 more
core +1 more source
Scientific Reports, 2018 Endothelial dysfunction contributes to sepsis outcome. Metabolic phenotypes associated with endothelial dysfunction are not well characterised in part due to difficulties in assessing endothelial metabolism in situ.
Sarah McGarrity +8 more
doaj +1 more source
Endothelial dysfunction in diabetic erectile dysfunction [PDF]
International Journal of Impotence Research, 2006 Erectile dysfunction (ED) is highly prevalent in diabetes mellitus. Pathophysiological mechanisms underlying diabetes-associated ED are in large part due to endothelial dysfunction, which functionally refers to the inability of the endothelium to produce vasorelaxing messengers and to maintain vasodilation and vascular homeostasis.
B, Musicki, A L, Burnett
openaire +2 more sources
Treatment of denture-related stomatitis improves endothelial function assessed by flow-mediated vascular dilation [PDF]
, 2016 Introduction: The presence of oral inflammation has recently been linked with the pathogenesis of cardiovascular diseases. While numerous studies have described links between periodontitis and endothelial dysfunction, little is known about the influence ...
Czesnikiewicz-Guzik, Marta +9 more
core +3 more sources
Redox Biology, 2018 The accumulation of uremic toxins in chronic kidney disease (CKD) induces inflammation, oxidative stress and endothelial dysfunction, which is a key step in atherosclerosis.
Mengjie Huang +5 more
doaj +1 more source
Effective treatment of edema and endothelial barrier dysfunction with imatinib [PDF]
, 2012 Background-Tissue edema and endothelial barrier dysfunction as observed in sepsis and acute lung injury carry high morbidity and mortality, but currently lack specific therapy.
Aman, J. +9 more
core +1 more source
Journal of Central Nervous System Disease, 2020 Background: In addition to the reduced energy production, characteristic of mitochondrial disorders, nitric oxide (NO) deficiency can occur as well. The NO produced by vascular endothelial cells relaxes vascular smooth muscles, resulting in vasodilation ...
Fatma Al Jasmi +5 more
doaj +1 more source